Of Snails, Earthworms, and Men: Insights into Strategies to Preserve Water [0.03%]
关于蜗牛、蚯蚓和人类的启示：水资源保护策略的思考
Christian Delles,Giacomo Rossitto
Christian Delles
Suzann Duan,Karen Rico,Juanita L Merchant
Suzann Duan
Abetted by widespread usage of acid-suppressing proton pump inhibitors (PPIs), the mitogenic actions of the peptide hormone gastrin are being revisited as a recurring theme in various gastrointestinal (GI) malignancies. While pathological g...
Ole H Petersen
Ole H Petersen
Mitochondrial P2X7 Receptor Localization Modulates Energy Metabolism Enhancing Physical Performance [0.03%]
线粒体P2X7受体的定位调节能量代谢增强体力性能
Alba Clara Sarti,Valentina Vultaggio-Poma,Simonetta Falzoni et al.
Alba Clara Sarti et al.
Basal expression of the P2X7 receptor (P2X7R) improves mitochondrial metabolism, Adenosine 5'-triphosphate (ATP) synthesis, and overall fitness of immune and non-immune cells. We investigated P2X7R contribution to energy metabolism and subc...
Iatrogenic Iron Promotes Neurodegeneration and Activates Self-Protection of Neural Cells against Exogenous Iron Attacks [0.03%]
医源性铁促进神经退行性病变并激活神经细胞对胞外铁攻击的自我保护作用
Maosheng Xia,Shanshan Liang,Shuai Li et al.
Maosheng Xia et al.
Metal implants are used worldwide, with millions of nails, plates, and fixtures grafted during orthopedic surgeries. Iron is the most common element of these metal implants. As time passes, implants can be corroded and iron can be released....
Heating Up to Heal-Acute Heat Exposure Increases Hepatic Mitophagy Resulting in Hormetic Improvements in Mitochondrial Bioenergetic Efficiency [0.03%]
加热以治疗-急性热暴露增加肝细胞自噬从而提高线粒体生物能量效率
Kelsey H Fisher-Wellman
Kelsey H Fisher-Wellman
Astrocytic-Neuronal Teamwork Against External Iron Attacks: Does It Always Work? [0.03%]
胶质细胞-神经元协作应对外来铁攻击：总有效吗？
Seojin Lee,Gabor G Kovacs
Seojin Lee
Csaba Szabo
Csaba Szabo
Guido Kroemer,Alexei Verkhratsky
Guido Kroemer
Hydrogen Sulfide Upregulates Acid-sensing Ion Channels via the MAPK-Erk1/2 Signaling Pathway [0.03%]
氢硫化物通过MAPK-Erk1 / 2信号通路调节酸感应离子通道的表达
Zhong Peng,Stephan Kellenberger
Zhong Peng
Hydrogen sulfide (H2S) emerged recently as a new gasotransmitter and was shown to exert cellular effects by interacting with proteins, among them many ion channels. Acid-sensing ion channels (ASICs) are neuronal voltage-insensitive Na+ chan...