Plasma of COVID-19 Patients Does Not Alter Electrical Resistance of Human Endothelial Blood-Brain Barrier In Vitro [0.03%]
COVID-19患者的血浆不会改变人源性脑屏障的电阻力特性
Agnė Pociūtė,Karolina Kriaučiūnaitė,Aida Kaušylė et al.
Agnė Pociūtė et al.
The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 instigated the most serious global health crisis. Clinical presentation of COVID-19 frequently includes severe neurological and ne...
Ole H Petersen
Ole H Petersen
POMC Neuron BBSome Regulation of Body Weight is Independent of its Ciliary Function [0.03%]
POMC神经元BBSome对体重的调节独立于它的纤毛功能
Deng-Fu Guo,Paul A Williams,Connor Laule et al.
Deng-Fu Guo et al.
The BBSome, a complex of several Bardet-Biedl syndrome (BBS) proteins including BBS1, has emerged as a critical regulator of energy homeostasis. Although the BBSome is best known for its involvement in cilia trafficking, through a process t...
The 2023 Walter B. Cannon Award Lecture: Mechanisms Regulating Vascular Function and Blood Pressure by the PPARγ-RhoBTB1-CUL3 Pathway [0.03%]
2023年Walter B. Cannon奖讲座：PPARγ-RhoBTB1-CUL3通路调控血管功能及血压的机制
Curt D Sigmund
Curt D Sigmund
Human genetic and clinical trial data suggest that peroxisome proliferator activated receptor γ (PPARγ), a nuclear receptor transcription factor plays an important role in the regulation of arterial blood pressure. The examination of a se...
Cannabigerolic Acid (CBGA) Inhibits the TRPM7 Ion Channel Through its Kinase Domain [0.03%]
大麻酸(CBGA)通过其激酶结构域抑制TRPM7离子通道
Sayuri Suzuki,Clay Wakano,Mahealani K Monteilh-Zoller et al.
Sayuri Suzuki et al.
Cannabinoids are a major class of compounds produced by the plant Cannabis sativa. Previous work has demonstrated that the main cannabinoids cannabidiol (CBD) and tetrahydrocannabinol (THC) can have some beneficial effects on pain, inflamma...
Temporal Dynamics and Therapeutic Implications of Phrenic Long-Term Facilitation in Respiratory Control [0.03%]
呼吸控制中迷走神经长时程强化的动态变化及治疗意义
Hemalatha Bhagavan,Nicholas J Burgraff,Jan-Marino Ramirez
Hemalatha Bhagavan
Neuromuscular Dysfunction Precedes Cognitive Impairment in a Mouse Model of Alzheimer's Disease [0.03%]
阿尔茨海默病小鼠模型中神经肌肉功能障碍先于认知障碍出现
Matthew H Brisendine,Anna S Nichenko,Aloka B Bandara et al.
Matthew H Brisendine et al.
Alzheimer's disease (AD) develops along a continuum that spans years prior to diagnosis. Decreased muscle function and mitochondrial respiration occur years earlier in those that develop AD; however, it is unknown what causes these peripher...
Julia V Gerasimenko,Oleg V Gerasimenko
Julia V Gerasimenko
Cardiac Timeless Trans-Organically Regulated by miR-276 in Adipose Tissue Modulates Cardiac Function [0.03%]
脂肪组织中调控心脏的miR-276介导跨器官时差作用调节心功能
Chao Tang,Qiufang Li,Xiaoya Wang et al.
Chao Tang et al.
The interconnection between cardiac function and circadian rhythms is of great importance. While the role of the biological clock gene Timeless (Tim) in circadian rhythm has been extensively studied, its impact on cardiac function remains l...
ORAI1 Crac Channel in Immune Cell is a Therapeutic Target for Pancreatitis-Associated Acute Lung Injury [0.03%]
免疫细胞中的ORAI1钙释放激活钙通道是急性胰腺炎相关性肺损伤的治疗靶点
Shuang Peng,Lu Ke,Weiqin Li
Shuang Peng