Mrunmayee R Kandalgaonkar,Beng San Yeoh,Bina Joe et al.
Mrunmayee R Kandalgaonkar et al.
Global prevalence of hypertension is on the rise, burdening healthcare, especially in developing countries where infectious diseases, such as malaria, are also rampant. Whether hypertension could predispose or increase susceptibility to mal...
Carotid Body Function in Tyrosine Hydroxylase Conditional Olfr78 Knockout Mice [0.03%]
条件性奥弗兰受体78敲除小鼠肾上腺素能体系的功能研究
Olalla Colinas,Peter Mombaerts,José López-Barneo et al.
Olalla Colinas et al.
The Olfr78 gene encodes a G-protein-coupled olfactory receptor that is expressed in several ectopic sites. Olfr78 is one of the most abundant mRNA species in carotid body (CB) glomus cells. These cells are the prototypical oxygen (O2) sensi...
David M Pollock
David M Pollock
Joshua R Huot,Patrick D Livingston,Fabrizio Pin et al.
Joshua R Huot et al.
Thanks to recent progress in cancer research, most children treated for cancer survive into adulthood. Nevertheless, the long-term consequences of anticancer agents are understudied, especially in the pediatric population. We and others hav...
The Effects of Chloroquine and Hydroxychloroquine on ACE2-Related Coronavirus Pathology and the Cardiovascular System: An Evidence-Based Review [0.03%]
氯喹和羟氯喹对ACE2相关冠状病毒病理及心血管系统的影响：循证综述
Li Chen,Haiyan Chen,Shan Dong et al.
Li Chen et al.
The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a serious threat to global public health and there is currently no effective antiviral therapy. It ...
Endocytic uptake of SARS-CoV-2: the critical roles of pH, Ca2+, and NAADP [0.03%]
SARS-CoV-2内吞作用：pH、Ca²⁺和NAADP的关键作用
Ole H Petersen,Oleg V Gerasimenko,Julia V Gerasimenko
Ole H Petersen
The Reappraisal of the Reappraisal-CRAC Channels Are Activated by L-Type Ca2+ Channel Blockers, Reply to Bird et al [0.03%]
再评估的再评估 - CRAC 通道被L型Ca2+通道阻滞剂激活，回应Bird等人的观点
Mohamed Trebak,Khaled Machaca,Patrick G Hogan
Mohamed Trebak
High Salt Remodels Kidney Metabolism: Metabolite Fuel, Fate, and Signals [0.03%]
高盐重塑肾脏代谢：代谢物的燃料、命运和信号
Moritz Lassé,Markus M Rinschen
Moritz Lassé
Phosphodiesterases Mediate the Augmentation of Myogenic Constriction by Inhibitory G Protein Signaling and is Negatively Modulated by the Dual Action of RGS2 and 5 [0.03%]
磷酸二酯酶介导抑制性G蛋白信号加强肌源性收缩并受到RGS2和5的双重作用的负调控
Bo Sun,Nia Smith,Alethia J Dixon et al.
Bo Sun et al.
G protein regulation by regulators of G protein signaling (RGS) proteins play a key role in vascular tone maintenance. The loss of Gi/o and Gq/11 regulation by RGS2 and RGS5 in non-pregnant mice is implicated in augmented vascular tone and ...
Yazhou Zhang,Qianqian Wang,Hongjia Xue et al.
Yazhou Zhang et al.
The skeletal system is crucial for supporting bodily functions, protecting vital organs, facilitating hematopoiesis, and storing essential minerals. Skeletal homeostasis, which includes aspects such as bone density, structural integrity, an...