The P2Y6 Receptor as a Potential Keystone in Essential Hypertension [0.03%]
P2Y6受体在原发性高血压中的可能作用及机制研究
Nuria Daghbouche-Rubio,Inés Álvarez-Miguel,Victor Alejandro Flores et al.
Nuria Daghbouche-Rubio et al.
Essential hypertension (HT) is a highly prevalent cardiovascular disease of unclear physiopathology. Pharmacological studies suggest that purinergic P2Y6 receptors (P2ry6) play important roles in cardiovascular function and may contribute t...
PARticularly Forceful: PAR1 Drives Glomerular Mesangial Cell Contractility [0.03%]
特别强劲的:PAR1驱动肾小球系膜细胞收缩力
Amanda P Waller,Kaushik Muralidharan,Bryce A Kerlin
Amanda P Waller
Sulfonylurea Receptor Pharmacology Alters the Performance of Two Central Pattern Generating Circuits in Cancer borealis [0.03%]
磺酰脲受体药理学改变了Cancer borealis的两个中央图案生成电路的表现形式
Sonal Kedia,Naziru M Awal,Jackie Seddon et al.
Sonal Kedia et al.
Neuronal activity and energy supply must maintain a fine balance for neuronal fitness. Various channels of communication between the two could impact network output in different ways. Sulfonylurea receptors (SURs) are a modification of ATP-...
A Skeletal Muscle-Mediated Anticontractile Response on Vascular Tone: Unraveling the Lactate-AMPK-NOS1 Pathway in Femoral Arteries [0.03%]
骨骼肌介导的抗收缩反应对血管张力的影响:股动脉乳酸-AMPK-NOS1通路的揭示
Milene T Fontes,Tiago J Costa,Ricardo B de Paula et al.
Milene T Fontes et al.
The regulation of vascular tone by perivascular tissues is a complex interplay of various paracrine factors. Here, we investigate the anti-contractile effect of skeletal muscle surrounding the femoral and carotid arteries and its underlying...
Regulation of Kv1.2 Redox-Sensitive Gating by the Transmembrane Lectin LMAN2 [0.03%]
LMAN2调控Kv1.2的氧化还原门控作用
Shawn M Lamothe,Damayantee Das,Anson A Wong et al.
Shawn M Lamothe et al.
Voltage gated potassium (Kv)1.2 channels influence excitability and action potential propagation in the nervous system. Unlike closely related Kv1 channels, Kv1.2 exhibits highly variable voltage-dependence of gating, attributed to regulati...
MoTrPAC Animal Aerobic Exercise Protocol and Biorepository: A Novel Resource for Uncovering Systemic Adaptations to Aerobic Exercise and Extending Healthspan [0.03%]
莫特帕克动物有氧运动方案和生物库:揭示有氧运动的全身性适应并延长健康寿命的新资源
Robert T Mankowski,Raymond Jones,Thomas W Buford
Robert T Mankowski
Samuel B Stephens
Samuel B Stephens
Exploring Circadian Changes in Muscle Physiology: Methodological Considerations [0.03%]
肌生理昼夜变化的研究方法学考虑因素
Mark R Viggars,Karyn A Esser
Mark R Viggars
Aparna Tiwari,Auley De,Abhinav Sinha
Aparna Tiwari
Impaired Neurocirculatory Control in Chronic Kidney Disease: New Evidence for Blunted Sympathetic Baroreflex and Reduced Sympathetic Transduction [0.03%]
慢性肾脏病中神经循环控制受损:交感神经张力过高、迷走神经过低的新证据及交感神经变压感受器反射迟钝和交感神经转导降低的最新证据
Jeann L Sabino-Carvalho,Elsa Mekonnen,Matias Zanuzzi et al.
Jeann L Sabino-Carvalho et al.
Chronic kidney disease (CKD) is characterized by over-activation of the sympathetic nervous system (SNS) that increases cardiovascular risk. Whether sympathetic baroreflex sensitivity (sBRS) is impaired or intact in CKD remains under-studie...