Influence of sire fertility on the metabolism of in vitro produced embryos [0.03%]
公牛的生育能力对体外生产胚胎代谢的影响
Quinn A Hoorn,Elena O&#x;Callaghan,David A Kenny et al.
Quinn A Hoorn et al.
Bull field fertility varies greatly and is largely influenced by differences in early embryo survival rather than fertilization failure alone. We, therefore, investigated whether sire fertility status is reflected in the metabolomic profile...
Trophoblast stem cells and syncytiotrophoblasts lack inflammatory responses to LPS but retain robust interferon-mediated antiviral immunity [0.03%]
滋养层干细胞和合体滋养层细胞缺乏对LPS的炎症反应但保留了强烈的干扰素介导的抗病毒免疫能力
Cristine R Camp,Joshua Baskaran,Matthew Brown et al.
Cristine R Camp et al.
Early pregnancy requires a tightly regulated pro-inflammatory environment shared between the primitive placenta and decidua. While immune balance supports successful implantation and placental invasion, disruptions in immune signaling durin...
Late-Stage Vacuolization as a Compaction-Dependent Prognostic Marker for Day-4 Embryo Selection [0.03%]
基于第4天胚胎选择的晚期囊化作为依赖细胞紧密连接的预后标志物
Yasong Geng,Aixin Yang,Fangfang Dai et al.
Yasong Geng et al.
Abstract: This study aimed to evaluate the prognostic value of late-stage vacuolization in Day 4 embryos relative to compaction status. We retrospectively analyzed 9,779 embryos from 2,409 patients undergoing fresh D4 tra...
Peripheral cytokines as candidate biomarkers for recurrent pregnancy loss [0.03%]
外周细胞因子作为复发性流产的候选生物标志物
Danai Bagkou Dimakou,Jennifer Tamblyn,David Lissauer et al.
Danai Bagkou Dimakou et al.
Abstract: A current working hypothesis in recurrent pregnancy loss (RPL) suggests immune dysregulation, underlain by a pro-inflammatory cytokine shift in TH cells. NK cells, which are primary immune effectors throughout p...
Fatima Aljassim,Charlotte H Rigby,Josephine A Drury et al.
Fatima Aljassim et al.
Abstract: Hydrosalpinx is a chronic pathological manifestation seen in approximately 30% of tubal disease cases. In addition to contributing to infertility and pelvic pain, hydrosalpinx has been associated with early preg...
ASSESSING CONCORDANCE OF GENETIC PARAMETERS BETWEEN TROPHECTODERM AND INNER CELL MASS IN MORPHOLOGICALLY SCORED DAY-5 EMBRYOS VIA NGS [0.03%]
通过高通量测序评估囊胚期胚胎细胞滋养外胚层和内细胞团的遗传一致性
Nicole Salameh,Athina Theodosiou,Ludmila Kousoulidou et al.
Nicole Salameh et al.
Abstract: Preimplantation genetic testing for aneuploidies (PGT-A) is used for embryo selection, on a 5-10 cell biopsy from the trophectoderm (TE) which later forms the placenta. Whether this biopsy reflects the inner cel...
Prevalence of Sexual Dysfunction and Its Association with Fertility Quality of Life Among Infertile Men in Henan, China [0.03%]
中国河南男性不育患者性功能障碍的患病率及其与生育生命质量的关系
Zhongxin Wang,Xuan Su,Ruonan Li et al.
Zhongxin Wang et al.
Infertility is a global public health issue, with male factors contributing to about 50% of cases. Yet, studies on fertility quality of life (FertiQoL), sexual dysfunction (SD), and their interconnection remain understudied in China, especi...
Toward Microbiome-Informed Strategies for Predicting and Preventing Pregnancy Complications [0.03%]
基于微生物组的策略预测和预防妊娠并发症
G L Ruschman,J A Bittor,D S Charnock-Jones et al.
G L Ruschman et al.
Abstract: Despite the prevalence of pregnancy complications, including miscarriage, stillbirth, preeclampsia (PE), fetal growth restriction (FGR), and preterm birth (PTB), current predictive tools remain limited. This und...
Higher BMI is associated with vaginal microbiome alterations in women with PCOS [0.03%]
BMI较高与PCOS患者阴道微生态改变有关
Marta Spochacz-Santoro,Anna Szeliga,Magdalena Durda-Masny et al.
Marta Spochacz-Santoro et al.
Abstract: Polycystic ovary syndrome (PCOS) is commonly associated with obesity and metabolic disturbances. Although gut and vaginal microbiome changes have been linked to PCOS, the independent role of body mass index in t...
Combined Nonoxynol-9 and Antimicrobial Peptide LL-37 for Barrier Contraception [0.03%]
结合Nonoxynol-9和抗菌肽LL-37作为避孕屏障防护剂
Murong Xu,Carol Pui Shan Chan,Luping Cong et al.
Murong Xu et al.
Abstract: Birth control and sexually transmitted infections are global concerns. Nonoxynol-9 is the most commonly used component in spermicides, with controversial safety and efficacy. LL-37 has been considered the most p...