Protease inhibitor plasma concentrations associate with COVID-19 infection [0.03%]
蛋白酶抑制剂血药浓度与新冠病毒感染有关
Nicholas R Medjeral-Thomas,Anne Troldborg,Annette G Hansen et al.
Nicholas R Medjeral-Thomas et al.
Protease inhibitors influence a range of innate immunity and inflammatory pathways. We quantified plasma concentrations of key anti-inflammatory protease inhibitors in chronic haemodialysis patients with coronavirus disease 2019 (COVID-19)....
Valeria Mondelli,Carmine M Pariante
Valeria Mondelli
Long-Coronavirus Disease (Long-COVID) is becoming increasingly recognized due to the persistence of symptoms such as profound fatigue, neurocognitive difficulties, muscle pains and weaknesses and depression, which would last beyond 3-12 wee...
The role and uses of antibodies in COVID-19 infections: a living review [0.03%]
抗体在新冠肺炎感染中的作用和用途：动态综述
D Oliver Scourfield,Sophie G Reed,Max Quastel et al.
D Oliver Scourfield et al.
Coronavirus disease 2019 has generated a rapidly evolving field of research, with the global scientific community striving for solutions to the current pandemic. Characterizing humoral responses towards SARS-CoV-2, as well as closely relate...
Impact of obesity and SARS-CoV-2 infection: implications for host defence - a living review [0.03%]
肥胖与SARS-CoV-2感染对宿主防御的影响：述评
Felix Clemens Richter,Aljawharah Alrubayyi,Alicia Teijeira Crespo;Oxford-Cardiff COVID- Literature Consortium;Sarah Hulin-Curtis
Felix Clemens Richter
The role of obesity in the pathophysiology of respiratory virus infections has become particularly apparent during the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, where obese patients are twice as likely t...
Innate immunology in COVID-19-a living review. Part II: dysregulated inflammation drives immunopathology [0.03%]
COVID-19的先天免疫学（Living Review系列）：第2部分：过度炎症驱动免疫病理学
Patrícia R S Rodrigues,Aljawharah Alrubayyi,Ellie Pring et al.
Patrícia R S Rodrigues et al.
The current pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a global health crisis and will likely continue to impact public health for years. As the effectiveness...
Innate immunology in COVID-19-a living review. Part I: viral entry, sensing and evasion [0.03%]
COVID-19的先天免疫学：动态综述 第I部分：病毒入侵、识别和逃逸
Clarissa Coveney,Michel Tellier,Fangfang Lu et al.
Clarissa Coveney et al.
The coronavirus infectious disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains a world health concern and can cause severe disease and high mortality in susceptible groups. While v...
Daniel M Altmann
Daniel M Altmann
The majority of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 exposed individuals mount an antibody response within around 2-weeks and spike antigen-binding responses correlate well with functional virus neutralization. A mino...
The emerging role of group 3 innate lymphoid cells in the neonate: interaction with the maternal and neonatal microbiome [0.03%]
新生儿第3组固有淋巴样细胞的作用及其与母体和新生儿微生物群的相互作用
Julie Mirpuri
Julie Mirpuri
Innate lymphoid cells (ILCs) are critical for host defense and are notably important in the context of the newborn when adaptive immunity is immature. There is an increasing evidence that development and function of group 3 ILCs (ILC3) can ...
The role of pseudotype neutralization assays in understanding SARS CoV-2 [0.03%]
假型中和试验在理解新冠病毒作用中的角色
Diego Cantoni,Martin Mayora-Neto,Nigel Temperton
Diego Cantoni
Claire F Pearson,Rebecca Jeffery;Oxford-Cardiff COVID- Literature Consortium;Emily E Thornton
Claire F Pearson
COVID-19 was initially characterized as a disease primarily of the lungs, but it is becoming increasingly clear that the SARS-CoV2 virus is able to infect many organs and cause a broad pathological response. The primary infection site is li...