Functional characterization of the DUF1127-containing small protein YjiS of Salmonella Typhimurium [0.03%]
含DUF1127结构域的小分子量蛋白YjiS的系统表征
Elisa Venturini,Sandra Maaß,Thorsten Bischler et al.
Elisa Venturini et al.
Bacterial small proteins impact diverse physiological processes, however, technical challenges posed by small size hampered their systematic identification and biochemical characterization. In our quest to uncover small proteins relevant fo...
Fernando Baquero,Gabriel S Bever,Victor de Lorenzo et al.
Fernando Baquero et al.
Evolutionary processes acting on populations of organized molecules preceded the origin of living organisms. These prebiotic entities were independently and repeatedly produced [i.e. (re)-produced] by the assembly of their components, follo...
Martin Klapper,Pierre Stallforth
Martin Klapper
Microbial natural products-low molecular weight compounds biosynthesized by microorganisms-form the foundation of important modern therapeutics, including antibiotics, immunomodulators, and anti-cancer agents. This perspective discusses and...
Tracking the uptake of labelled host-derived extracellular vesicles by the human fungal pathogen Aspergillus fumigatus [0.03%]
追踪宿主衍生的标记细胞外囊泡在人类真菌病原体烟曲霉中的摄取情况
Corissa Visser,Flora Rivieccio,Thomas Krüger et al.
Corissa Visser et al.
Extracellular vesicles (EVs) have gained attention as facilitators of intercellular as well as interkingdom communication during host-microbe interactions. Recently we showed that upon infection, host polymorphonuclear leukocytes produce an...
Compiling a versatile toolbox for inducible gene expression in Methanosarcina mazei [0.03%]
编译一个用于甲烷菌(Methanosarcina mazei)可诱导基因表达的多功能工具箱
Johanna Hüttermann,Ruth Schmitz
Johanna Hüttermann
Methanosarcina mazei is a model organism, providing a platform to explore methanoarchaeal regulation mechanisms on the transcriptional and translational level. This study investigates and evaluates various molecular tools to allow inducible...
Inferring bacterial interspecific interactions from microcolony growth expansion [0.03%]
根据微菌落生长扩张推断细菌种间相互作用
Tania Miguel Trabajo,Isaline Guex,Manupriyam Dubey et al.
Tania Miguel Trabajo et al.
Bacterial species interactions significantly shape growth and behavior in communities, determining the emergence of community functions. Typically, these interactions are studied through bulk population measurements, overlooking the role of...
Pyoverdine-antibiotic combination treatment: its efficacy and effects on resistance evolution in Escherichia coli [0.03%]
吡 Overdine-抗生素联合治疗及其对大肠杆菌抗药性进化的疗效和影响
Vera Vollenweider,Flavie Roncoroni,Rolf Kümmerli
Vera Vollenweider
Antibiotic resistance is a growing concern for global health, demanding innovative and effective strategies to combat pathogenic bacteria. Pyoverdines, iron-chelating siderophores produced by environmental Pseudomonas spp., present a novel ...
Acetylomics reveals an extensive acetylation diversity within Pseudomonas aeruginosa [0.03%]
乙酰化组学揭示了潘氏气囊虫中广泛的乙酰化多样性
Nand Broeckaert,Hannelore Longin,Hanne Hendrix et al.
Nand Broeckaert et al.
Bacteria employ a myriad of regulatory mechanisms to adapt to the continuously changing environments that they face. They can, for example, use post-translational modifications, such as Nε-lysine acetylation, to alter enzyme activity. Alth...
Microbial markets: socio-economic perspective in studying microbial communities [0.03%]
微生物市场的研究：从社会经济视角探讨微生物群落
Fariha Mostafa,Aileen Krüger,Tim Nies et al.
Fariha Mostafa et al.
Studying microbial communities through a socio-economic lens, this paper draws parallels with human economic transactions and microbes' race for resources. Extending the 'Market Economy' concept of social science to microbial ecosystems, th...
Microbial hub signaling compounds: natural products disproportionally shape microbiome composition and structure [0.03%]
微生物信号传导核心化合物：天然产物会不成比例地改变微生物组的组成和结构
Axel A Brakhage
Axel A Brakhage
Microbiomes are shaped by abiotic factors like nutrients, oxygen availability, pH, temperature, and so on, but also by biotic factors including low molecular weight organic compounds referred to as natural products (NPs). Based on genome an...