A global data-driven census of Salmonella small proteins and their potential functions in bacterial virulence [0.03%]
全球基于数据驱动的沙门氏菌小蛋白质普查及其在细菌毒力中的潜在功能
Elisa Venturini,Sarah L Svensson,Sandra Maaß et al.
Elisa Venturini et al.
Small proteins are an emerging class of gene products with diverse roles in bacterial physiology. However, a full understanding of their importance has been hampered by insufficient genome annotations and a lack of comprehensive characteriz...
Mycobacterium tuberculosis infection triggers epigenetic changes that are enriched in a type I IFN signature [0.03%]
结核分枝杆菌感染引发表观遗传学改变并富集I型干扰素特征
Katrina Madden,Rayan El Hamra,Stefania Berton et al.
Katrina Madden et al.
Tuberculosis, a deadly infectious lung disease caused by Mycobacterium tuberculosis (Mtb), remains the leading cause of bacterial disease-related deaths worldwide. Mtb reprograms and disables key antibacterial response pathways, many of whi...
Cryptococcus neoformans releases proteins during intracellular residence that affect the outcome of the fungal-macrophage interaction [0.03%]
新生隐球菌在胞内驻留期间释放蛋白质从而影响真菌-巨噬细胞相互作用的转归
Eric H Jung,Yoon-Dong Park,Quigly Dragotakes et al.
Eric H Jung et al.
Cryptococcus neoformans is a facultative intracellular pathogen that can replicate and disseminate in mammalian macrophages. In this study, we analyzed fungal proteins identified in murine macrophage-like cells after infection with C. neofo...
Simulating the impact of non-pharmaceutical interventions limiting transmission in COVID-19 epidemics using a membrane computing model [0.03%]
使用膜计算模型模拟限制COVID-19疫情传播的非药物干预的影响
M Campos,J M Sempere,J C Galán et al.
M Campos et al.
Epidemics caused by microbial organisms are part of the natural phenomena of increasing biological complexity. The heterogeneity and constant variability of hosts, in terms of age, immunological status, family structure, lifestyle, work act...
An overview of Salmonella enterica metal homeostasis pathways during infection [0.03%]
鼠伤寒沙门氏菌感染期间金属离子稳态途径综述
Olivier Cunrath,Jacob D Palmer
Olivier Cunrath
Nutritional immunity is a powerful strategy at the core of the battlefield between host survival and pathogen proliferation. A host can prevent pathogens from accessing biological metals such as Mg, Fe, Zn, Mn, Cu, Co or Ni, or actively int...
Jeffrey Almond,Jörg Hacker,Colin Harwood et al.
Jeffrey Almond et al.
In December 2019, a working group of the European Academy of Microbiology assembled to discuss various aspects of vaccines and vaccinations. The meeting was organised by Jörg Hacker and Eliora Z. Ron and took place in the offices of the Le...