Human milk oligosaccharides induce acute yet reversible compositional changes in the gut microbiota of conventional mice linked to a reduction of butyrate levels [0.03%]
人乳寡糖可诱导常规小鼠肠道菌群组成发生急性和短暂的变化并导致丁酸盐水平降低
Andrea Qvortrup Holst,Harshitha Jois,Martin Frederik Laursen et al.
Andrea Qvortrup Holst et al.
Human Milk Oligosaccharides (HMOs) are glycans with prebiotic properties known to drive microbial selection in the infant gut, which in turn influences immune development and future health. Bifidobacteria are specialized in HMO degradation ...
Bacterial methyltransferases: from targeting bacterial genomes to host epigenetics [0.03%]
细菌甲基转移酶：从靶向细菌基因组到宿主表观遗传学
Monica Rolando,Cristina Di Silvestre,Laura Gomez-Valero et al.
Monica Rolando et al.
Methyltransferase (MTases) enzymes transfer methyl groups particularly on proteins and nucleotides, thereby participating in controlling the epigenetic information in both prokaryotes and eukaryotes. The concept of epigenetic regulation by ...
Lipid A heterogeneity and its role in the host interactions with pathogenic and commensal bacteria [0.03%]
脂质A的异质性及其在宿主与病原菌和共生菌相互作用中的作用
Sukumar Saha,Elder Pupo,Afshin Zariri et al.
Sukumar Saha et al.
Lipopolysaccharide (LPS) is for most but not all Gram-negative bacteria an essential component of the outer leaflet of the outer membrane. LPS contributes to the integrity of the outer membrane, which acts as an effective permeability barri...
Sarah Wettstadt
Sarah Wettstadt
About the scientific life of Judith Behnsen. © The Author(s) 2022. Published by Oxford University Press on behalf of FEMS.
Hidden in plain sight: challenges in proteomics detection of small ORF-encoded polypeptides [0.03%]
隐藏在视野中：小ORF编码多肽质谱鉴定的挑战
Igor Fijalkowski,Patrick Willems,Veronique Jonckheere et al.
Igor Fijalkowski et al.
Genomic studies of bacteria have long pointed toward widespread prevalence of small open reading frames (sORFs) encoding for short proteins,
Metagenomic survey of the microbiome of ancient Siberian permafrost and modern Kamchatkan cryosols [0.03%]
西伯利亚永久冻土和堪察加半原冰土微生物群落的元基因组调查
Sofia Rigou,Eugène Christo-Foroux,Sébastien Santini et al.
Sofia Rigou et al.
In the context of global warming, the melting of Arctic permafrost raises the threat of a reemergence of microorganisms some of which were shown to remain viable in ancient frozen soils for up to half a million years. In order to evaluate t...
Simulating the efficacy of vaccines on the epidemiological dynamics of SARS-CoV-2 in a membrane computing model [0.03%]
基于膜计算模型模拟疫苗对SARS-CoV-2流行病学动力学的影响效力
Marcelino Campos,José M Sempere,Juan C Galán et al.
Marcelino Campos et al.
Membrane computing is a natural computing procedure inspired in the compartmental structure of living cells. This approach allows mimicking the complex structure of biological processes, and, when applied to transmissible diseases, can simu...
Correction to: Living a bacterial lifestyle as an academic researcher [0.03%]
谨防掉入科研细菌式生活的陷阱——一名科研老兵的心里话（论点）
[This corrects the article DOI: 10.1093/femsml/uqac012.]. © The Author(s) 2022. Published by Oxford University Press on behalf of FEMS.
Published Erratum
microLife. 2022 Oct 12:3:uqac017. DOI:10.1093/femsml/uqac017 2022
Nonessential tRNA and rRNA modifications impact the bacterial response to sub-MIC antibiotic stress [0.03%]
非必要的tRNA和rRNA修饰影响细菌对低于最小抑菌浓度的抗生素胁迫的响应
Anamaria Babosan,Louna Fruchard,Evelyne Krin et al.
Anamaria Babosan et al.
Antimicrobial resistance develops as a major problem in infectious diseases treatment. While antibiotic resistance mechanisms are usually studied using lethal antibiotic doses, lower doses allowing bacterial growth are now considered as fac...