Recent advances and perspectives in nucleotide second messenger signaling in bacteria [0.03%]
细菌核苷酸第二信使信号传导的最新进展和前景展望
Regine Hengge,Mihaela Pruteanu,Jörg Stülke et al.
Regine Hengge et al.
Nucleotide second messengers act as intracellular 'secondary' signals that represent environmental or cellular cues, i.e. the 'primary' signals. As such, they are linking sensory input with regulatory output in all living cells. The amazing...
Osmotic stress responses and the biology of the second messenger c-di-AMP in Streptomyces [0.03%]
有关链霉菌渗透压应激反应及第二信使c-di-AMP生物学的研究
Sukanya Bhowmick,Mary L Shenouda,Natalia Tschowri
Sukanya Bhowmick
Streptomyces are prolific antibiotic producers that thrive in soil, where they encounter diverse environmental cues, including osmotic challenges caused by rainfall and drought. Despite their enormous value in the biotechnology sector, whic...
Characterization of membrane vesicles in Alteromonas macleodii indicates potential roles in their copiotrophic lifestyle [0.03%]
表征Alteromonas macleodii的膜囊泡表明其可能在丰富的生境中发挥作用
Eduard Fadeev,Cécile Carpaneto Bastos,Jennifer H Hennenfeind et al.
Eduard Fadeev et al.
Bacterial membrane vesicles (MVs) are abundant in the oceans, but their potential functional roles remain unclear. In this study we characterized MV production and protein content of six strains of Alteromonas macleodii, a cosmopolitan mari...
Role of (p)ppGpp in antibiotic resistance, tolerance, persistence and survival in Firmicutes [0.03%]
(p)ppGpp在厚壁菌门抗生素抗性、耐受性、持留性和存活中的作用
Andrea Salzer,Christiane Wolz
Andrea Salzer
The stringent response and its signalling nucleotides, pppGpp and ppGpp, have been the subject of intense research since the discovery of (p)ppGpp in 1969. Recent studies have revealed that the downstream events that follow (p)ppGpp accumul...
Ancestral reconstruction of the MotA stator subunit reveals that conserved residues far from the pore are required to drive flagellar motility [0.03%]
祖先重建MotA定子亚基揭示了孔外的保守残基对于驱动鞭毛运动是必需的
Md Imtiazul Islam,Pietro Ridone,Angela Lin et al.
Md Imtiazul Islam et al.
The bacterial flagellar motor (BFM) is a rotary nanomachine powered by the translocation of ions across the inner membrane through the stator complex. The stator complex consists of two membrane proteins: MotA and MotB (in H+-powered motors...
Structural and functional diversity of bacterial cyclic nucleotide perception by CRP proteins [0.03%]
CRP蛋白通过环核苷酸感知的细菌结构和功能多样性
Elizaveta Krol,Laura Werel,Lars Oliver Essen et al.
Elizaveta Krol et al.
Cyclic AMP (cAMP) is a ubiquitous second messenger synthesized by most living organisms. In bacteria, it plays highly diverse roles in metabolism, host colonization, motility, and many other processes important for optimal fitness. The main...
Phylogenetic diversity of core rumen microbiota as described by cryo-ET [0.03%]
低温电子显微镜下的核心瘤胃微生物群体的系统发育多样性
Benedikt H Wimmer,Sarah Moraïs,Ran Zalk et al.
Benedikt H Wimmer et al.
Microbial taxonomy is critical for describing ecosystem composition, yet the link between taxonomy and properties of microbes, such as their cellular architecture, remains poorly defined. We hypothesized that the cellular architecture repre...
Sarah Wettstadt
Sarah Wettstadt
Sarah Wettstadt
Sarah Wettstadt
Antibiotic tolerance in environmentally stressed Bacillus subtilis: physical barriers and induction of a viable but nonculturable state [0.03%]
环境压力下枯草芽孢杆菌的抗生素耐受性：物理屏障和活性但非培养态的诱导
Luiza P Morawska,Oscar P Kuipers
Luiza P Morawska
Bacterial communities exposed to rapid changes in their habitat encounter different forms of stress. Fluctuating conditions of the microenvironment drive microorganisms to develop several stress responses to sustain growth and division, lik...