Resistance against aminoglycoside antibiotics via drug or target modification enables community-wide antiphage defense [0.03%]
通过药物或靶点修饰对抗氨基糖苷类抗生素可实现社区范围内的抗噬菌体防御
Larissa Kever,Qian Zhang,Aël Hardy et al.
Larissa Kever et al.
The ongoing arms race between bacteria and phages has forced bacteria to evolve a sophisticated set of antiphage defense mechanisms that constitute the bacterial immune system. In our previous study, we highlighted the antiphage properties ...
Coordinated regulation of osmotic imbalance by c-di-AMP shapes ß-lactam tolerance in Group B Streptococcus [0.03%]
c-di-AMP介导的渗透调节协调控制β内酰胺耐受性形成的机制研究
Terry Brissac,Cécile Guyonnet,Aymane Sadouni et al.
Terry Brissac et al.
Streptococcus agalactiae is among the few pathogens that have not developed resistance to ß-lactam antibiotics despite decades of clinical use. The molecular basis of this long-lasting susceptibility has not been investigated, and it is no...
Multiple variants of the type VII secretion system in Gram-positive bacteria [0.03%]
革兰氏阳性菌的类型 VII 分泌系统变异体
Stephen R Garrett,Andrew B Higginson,Tracy Palmer
Stephen R Garrett
Type VII secretion systems (T7SS) are found in bacteria across the Bacillota and Actinomycetota phyla and have been well described in Staphylococcus aureus, Bacillus subtilis, and pathogenic mycobacteria. The T7SS from Actinomycetota and Ba...
A cyanobacterial chemotaxis-like system controls phototactic orientation via phosphorylation of two antagonistic response regulators [0.03%]
一个类似细菌化学感受的系统通过磷酸化两个拮抗反应调节因子来控制向光性
Yu Han,Jonas Hammerl,Felicitas E Flemming et al.
Yu Han et al.
Photosynthetic cyanobacteria exhibit phototaxis, utilizing type IV pili (T4P) to navigate either toward or away from a light source. The Tax1 system is a chemotaxis-like signal transduction pathway that controls the switch in cell polarity,...
Time-series metaproteogenomics of a high-CO2 aquifer reveals active viruses with fluctuating abundances and broad host ranges [0.03%]
高二氧化碳含水层的时间序列元蛋白质基因组学揭示了活性病毒及其波动丰度和广泛的宿主范围
Carrie Julia Moore,Till L V Bornemann,Perla Abigail Figueroa-Gonzalez et al.
Carrie Julia Moore et al.
Ecosystems subject to mantle degassing are of particular interest for understanding global biogeochemistry, as their microbiomes are shaped by prolonged exposure to high CO2 and have recently been suggested to be highly active. While the ge...
Correction to: multireceptor phage cocktail against Salmonella enterica to circumvent phage resistance [0.03%]
Correction to: 用于 circumvent 阿尔法萨门肠杆菌的多受体噬菌体鸡尾酒疗法以克服噬菌体抗性
[This corrects the article DOI: 10.1093/femsml/uqae003.]. © His Majesty the King in Right of Canada, as represented by the Minister of Agriculture and A...
Published Erratum
microLife. 2024 May 22:5:uqae010. DOI:10.1093/femsml/uqae010 2024
Meeting report 'Microbiology 2023: from single cell to microbiome and host', an international interacademy conference in Würzburg [0.03%]
“微生物2023：从单细胞到菌群及宿主”国际院所合作会议报告（维尔茨堡）
Pascale Cossart,Jörg Hacker,David H Holden et al.
Pascale Cossart et al.
On September 20-22 September 2023, the international conference 'Microbiology 2023: from single cell to microbiome and host' convened microbiologists from across the globe for a very successful symposium, showcasing cutting-edge research in...
Functional redundancy revealed by the deletion of the mimivirus GMC-oxidoreductase genes [0.03%]
假病毒GMC-氧化还原酶基因缺失所揭示的功能冗余性
Jean-Marie Alempic,Hugo Bisio,Alejandro Villalta et al.
Jean-Marie Alempic et al.
The mimivirus 1.2 Mb genome was shown to be organized into a nucleocapsid-like genomic fiber encased in the nucleoid compartment inside the icosahedral capsid. The genomic fiber protein shell is composed of a mixture of two GMC-oxidoreducta...
Pablo Iturbe,Alvaro San Martín,Hiroshi Hamamoto et al.
Pablo Iturbe et al.
Bacteria synchronize the expression of genes with related functions by organizing genes into operons so that they are cotranscribed together in a single polycistronic messenger RNA. However, some cellular processes may benefit if the simult...
Salmonella enterica serovar Typhimurium ST313 sublineage 2.2 has emerged in Malawi with a characteristic gene expression signature and a fitness advantage [0.03%]
沙门氏菌在马拉维的一个特定基因表达特征和优势适应性中出现亚型 Salmonella enterica serovar Typhimurium ST313 下系 2.2
Benjamin Kumwenda,Rocío Canals,Alexander V Predeus et al.
Benjamin Kumwenda et al.
Invasive non-typhoidal Salmonella (iNTS) disease is a serious bloodstream infection that targets immune-compromised individuals, and causes significant mortality in sub-Saharan Africa. Salmonella enterica serovar Typhimurium ST313 causes th...