Antibacterial and Antioxidant Activities, Toxicity, and Physicochemical Properties of Crassocephalum montuosum (S Moore) Milne-Redh and Crassocephalum picridifolium (DC) S Moore [0.03%]
Crassocephalum montuosum (S Moore)米尔氏红山芹和Crassocephalum picridifolium (DC) 莫尔氏红山芹的抗菌和抗氧化活性，毒性及理化性质
Bashige Chiribagula Valentin,Bakari Amuri Salvius,Lumbu Simbi Jean Baptiste
Bashige Chiribagula Valentin
In traditional Congolese medicine, the plants Crassocephalum montuosum (CrasMon) and Crassocephalum picridifolium (CrasPic) are used to treat bacterial gastroenteritis. In the present study, the antibacterial and antioxidant activities as w...
The β3-Adrenergic Receptor: Structure, Physiopathology of Disease, and Emerging Therapeutic Potential [0.03%]
β3肾上腺素受体：结构、疾病生理病理及新兴治疗潜力
Julius T Dongdem,Axandrah E Etornam,Solomon Beletaa et al.
Julius T Dongdem et al.
The discovery and characterization of the signal cascades of the β-adrenergic receptors have made it possible to effectively target the receptors for drug development. β-Adrenergic receptors are a class A rhodopsin type of G protein-coupl...
Cytotoxic Effect of Trypanosoma cruzi Calcineurin B Against Melanoma and Adenocarcinoma Cells In Vitro [0.03%]
毕赤酵母分泌表达的克鲁兹锥虫钙调磷酸酶B的体外细胞毒效应
Mayela Serrano-Rodríguez,Jorge E Araya,Mauro Cortez et al.
Mayela Serrano-Rodríguez et al.
Chagas disease caused by the obligate intracellular flagellate protozoan Trypanozoma cruzi infects about 6 million people. From the 1930s to the present, the antitumor capacity of T. cruzi has been studied; however, the identification of th...
Octanoic Acid and Decanoic Acid Inhibit Tunicamycin-Induced ER Stress in Rat Aortic Smooth Muscle Cells [0.03%]
月桂酸和癸酸抑制内质网应激诱导的血管平滑肌细胞分化的作用及机制研究
Wanida Sukketsiri,Varomyalin Tipmanee,Panlekha Rungruang et al.
Wanida Sukketsiri et al.
ER stress is a crucial factor in the progression of vascular cell diseases. Notably, octanoic acid (OA; C8:0) and decanoic acid (DA; C10:0), prominent components of medium-chain fatty acids (MCFAs), may provide potential health benefits. Ho...
The Combination of Sorafenib and PGV-1 Inhibits the Proliferation of Hepatocellular Carcinoma Through c-Myc Suppression in an Additive Manner: In Vitro Studies [0.03%]
索拉非尼联合PGV-1通过加成抑制c-Myc来抑制肝癌细胞增殖：体外研究
Dhania Novitasari,Ikuko Nakamae,Noriko Yoneda-Kato et al.
Dhania Novitasari et al.
Hepatocellular carcinoma (HCC) is one of the most aggressive types of liver cancer, and it is frequently associated with upregulated c-Myc expression. Sorafenib (Sor) is commonly used to treat HCC, but many patients experienced mild to seve...
Baicalein Long-Circulating Liposomes Improve Histological and Functional Outcomes After Traumatic Brain Injury [0.03%]
黄芩素长循环脂质体改善创伤性脑损伤后的组织学和功能结果
Dong Yuan,Wenbo Xu,Faisal Raza et al.
Dong Yuan et al.
High mortality and disability have been principally linked with traumatic brain injury (TBI) with this condition being a principal issue in public health. Currently, there is no reliable pharmaceutical agent to salvage the damage caused by ...
Effect of Thai Herbal Remedy NL Inhibits Lipid Accumulation on 3T3-L1 Adipocyte Cells [0.03%]
NL草药抑制3T3-L1脂肪细胞中的脂质积累作用研究
Sakan Warinhomhoun,Kittikun Viwatpinyo,Nuttikarn Nokkaew et al.
Sakan Warinhomhoun et al.
Obesity is a global health concern, steadily rising and posing risks to various health conditions. Despite available antiobesity drugs, their withdrawal due to severe side effects highlights the need for safer alternatives. Natural products...
Saikosaponin-b2 Regulates the Proliferation and Apoptosis of Liver Cancer Cells by Targeting the MACC1/c-Met/Akt Signalling Pathway [0.03%]
补骨脂沙皂苷乙通过靶向MACC1/c-Met/Akt信号通路调节肝癌细胞增殖及凋亡作用机制研究
Yanxue Zhu,Xingzhi Lv,Ruifang Li et al.
Yanxue Zhu et al.
Saikosaponin-b2 (SS-b2), an active ingredient derived from the root of Radix Bupleuri, possesses antitumour, anti-inflammatory, antioxidative and hepatoprotective properties. We investigated the inhibition of tumour proliferation by SS-b2 a...
Black Mulberry (Morus nigra L.): A Review of Attributes as an Anticancer Agent to Encourage Pharmaceutical Development [0.03%]
黑桑树（墨果桑，Morus nigra L.）：作为抗癌剂的药用开发前景综述
Ana Paula Costa Rodrigues Ferraz,Patrícia de Oliveira Figueiredo,Nídia Cristiane Yoshida
Ana Paula Costa Rodrigues Ferraz
Recent considerations of natural sources as potential anticancer agents have arisen due to the origins of numerous drugs commonly used in chemotherapy. Plant-based drugs, in particular, have attracted attention for offering the advantage of...
Neuroprotective Effect of Benzyl Ferulate on Ischemia/Reperfusion Injury via Regulating NOX2 and NOX4 in Rats: A Potential Antioxidant for CI/R Injury [0.03%]
苯基 ferulate对缺血再灌注损伤的神经保护作用：通过调节NOX2和NOX4抗氧化防治CI/R损伤
Yu Xiang,Li Mao,Zhao-Hui Dai et al.
Yu Xiang et al.
Oxidative stress is a primary contributor to cerebral ischemia/reperfusion (CI/R) injury, and the use of antioxidants represents a crucial therapeutic strategy for managing CI/R injury. This study aims to explore the antioxidant effects of ...