Development of Curcumin Encapsulated Liposomes in Chlorhexidine-Loaded Organogel Using Ternary Phase Systems for Treatment of Omphalitis in Infants [0.03%]
使用三元相系统开发负载氯己定的有机凝胶中封装姜黄素的小窝状脂质体用于治疗婴儿脐炎
Ibilola Mary Cardoso-Daodu,Margaret Okonawan Ilomuanya
Ibilola Mary Cardoso-Daodu
Infections in infants, after childbirth, remain a leading cause of neonatal morbidity and mortality, globally. A soaring percentage of these infections arise from bacterial colonization of the umbilicus. Current therapy for omphalitis inclu...
Insights Into Genetic Variations of the OCT1 Gene in Metformin Poor Responders Among Bangladeshi Type 2 Diabetic Patients [0.03%]
孟加拉II型糖尿病患者中二甲双胍反应不良者OCT1基因变异的见解
Rokeya Begum,Arindita Das,Md Jahangir Alam et al.
Rokeya Begum et al.
Metformin is the most widely prescribed drug for the treatment of Type 2 diabetes mellitus (T2DM), but its response varies from person to person. This study aims to analyze the complete mutation spectrum of the OCT1 gene in metformin poor r...
Sargassum plagiophyllum Ethanolic Extract Enhances Wound Healing by Modulating FAK/Src/Akt/p38 and Rac1 Signaling in Keratinocytes HaCaT Cells [0.03%]
羊栖菜乙醇提取物通过调节FAK/Src/Akt/p38和Rac1信号通路增强HaCaT细胞伤口愈合作用
Furoida Moolsup,Wanida Sukketsiri,Wipawadee Sianglum et al.
Furoida Moolsup et al.
Recently, seaweed extracts have been found to have potential in skin benefits. This study, therefore, aimed to explore phytochemical analysis, antimicrobial, antioxidant, and wound healing properties of brown seaweed Sargassum plagiophyllym...
Method Development and Clinical Utility for Simultaneous Measurement of 21-Deoxycortisol, 17-Hydroxyprogesterone, Cortisol, and Cortisone Levels in Human Plasma Using UHPLC-MS/MS [0.03%]
基于UHPLC-MS/MS同时测定人血浆中21-脱氧皮质醇、17-羟孕酮、皮质醇和皮质osterone的检测方法建立及其临床应用价值评估
Syed N Alvi,Saleh Al Dgither,Ali Al-Odaib
Syed N Alvi
A simple and efficient validated assay for quantifying 21-deoxycortisol (21-DOC), 17-hydroxyprogesterone (17-OHP), cortisol, and cortisone in human plasma has been developed using ultra-high performance liquid chromatography coupled with ta...
Formulation Design, Optimization, and Evaluation of Solid Lipid Nanoparticles Loaded With an Antiviral Drug Tenofovir Using Box-Behnken Design for Boosting Oral Bioavailability [0.03%]
基于Box-Behnken设计的抗病毒药物替诺福韦固态脂质纳米粒口服递送系统以增强口服生物利用度及体内外抗病毒活性
Sri Rekha M,Sangeetha S
Sri Rekha M
Purpose: The current study aimed to improve the oral bioavailability of tenofovir (TNF), an antihuman immunodeficiency viral (HIV) drug, by integrating it into solid lipid nanoparticles (SLNs), an emerging lipid formulation. Method: The sug...
Antiplatelet Effects of a Combination of Sappan Wood (Caesalpinia sappan L.) and Red Ginger (Zingiber officinale var. Rubrum) Extracts in a High-Fat Diet-Induced Rat Model [0.03%]
降脂减肥药的研究——应用综合评分法筛选复方 Gambir 叶片与山楂叶口服单味和复方有效成分的降血脂及减肥作用
Meidi Utami Puteri,Nur Afifah,Anisa Qisti Mathriul et al.
Meidi Utami Puteri et al.
Background: Antithrombotic medications, including antiplatelet agents, are standard treatments for patients with hyperlipidemia who have a high risk of developing cardiovascular disease (CVD). The ongoing exploration of new antiplatelet age...
Ethanolic Extracts of Cissus quadrangularis Linn. (Vitaceae) Attenuate Vincristine-Induced Peripheral Neuropathy in Rats: An Evidence of the Antioxidant, Calcium Inhibitory, and Neuromodulatory Properties [0.03%]
Cissus quadrangularis Linn．（葡萄科）的乙醇提取物可减轻vincristine致大鼠外周神经病变：抗氧化、抑钙及神经营养作用证据
Feigni Youyi Marcelle Olga,Mbiantcha Marius,Yousseu Nana William et al.
Feigni Youyi Marcelle Olga et al.
Cissus quadrangularis Linn. (C. quadrangularis, Vitaceae) is a plant reported to treat injured tendons, broken bones, asthma, stomach ache, scurvy, and digestive disorders. The present study evaluated the antihyperalgesic effects of ethanol...
Identification, Synthesis, and Characterization of N-Formyl Mirabegron: A New Degradation Product Formed by Formic Acid Impurity in Pharmaceutical Excipients [0.03%]
富马酸米拉贝隆新降解产物N-_formyl_米拉贝隆的识别、合成与鉴定：赋形剂中甲酸杂质所致
Bashir Daoud Agha Dit Daoudy,Mohammad Ammar Al-Khayat,Ghassan Abo Chameh et al.
Bashir Daoud Agha Dit Daoudy et al.
This study demonstrated the impact of formic acid (FAc), a common reactive impurity in pharmaceutical excipients, on the stability of mirabegron (MB). The investigation of MB-excipient compatibility tests revealed the formation of a new deg...
Compliance of Pharmaceutical Manufacturing Companies to Good Manufacturing Practices in Heating, Ventilation, and Air-Conditioning Systems: The Case of Local Ethiopian Firms [0.03%]
埃塞俄比亚制药企业制造工艺中采暖、通风和空调系统的合规性研究：以当地企业为例
Desta Tune Tibesso,Tesfaye Gabriel,Tamrat Balcha Balla et al.
Desta Tune Tibesso et al.
Background: Good manufacturing practice (GMP) is a part of quality management that maintains product quality and manages it according to the criteria of fitness for use. The heating, ventilation, and air-conditioning (HVAC) system comprises...
Update on the Potential of Punica granatum L. Traditional Uses and Pharmacological Uses: A Review [0.03%]
关于 Punica granatum L.的传统用途和药理作用的最新研究进展综述
Abdulrahman Mahmoud Dogara,Harmand A Hama,Dogan Ozdemir
Abdulrahman Mahmoud Dogara
Since the dawn of civilization, humans have turned to plants as a reliable source of safe and efficient treatment for a wide variety of medical conditions. The medicinal value of Punica granatum has been recognized for some time. Inflammati...