Chondrotoxicity of Local Anesthetics: Liposomal Bupivacaine Is Less Chondrotoxic than Standard Bupivacaine [0.03%]
长效利多卡因软骨毒性与罗哌卡因和脂质包封布比卡因的比较研究
Travis Farmer,S Craig Morris,Robert Quigley et al.
Travis Farmer et al.
Objective: The purpose of this study is to determine whether (1) liposomal bupivacaine is chondrotoxic; (2) the chondrotoxicity of liposomal bupivacaine differs from standard bupivacaine; and (3) chondrotoxic effects are ...
Antioxidant Action and In Vivo Anti-Inflammatory and Antinociceptive Activities of Myrciaria floribunda Fruit Peels: Possible Involvement of Opioidergic System [0.03%]
Myrciaria floribunda果皮的抗氧化作用及体内抗炎和镇痛活性：可能涉及阿片样物质系统
Izabelly Bianca da Silva Santos,Bruno Santos Dos Santos,João Ricardhis Saturnino de Oliveira et al.
Izabelly Bianca da Silva Santos et al.
This work evaluated the antioxidant properties and in vivo antinociceptive and anti-inflammatory effects of extracts obtained from fruit peels of Myrciaria floribunda (H. West ex Willd.) O. Berg (Myrtaceae). This plant is popularly known in...
Novel Dimethylacetamide-Containing Formulation Improves Infraorbital Anaesthesia Efficacy in Rats with Periodontitis [0.03%]
含N,N-二甲基乙酰胺的新制剂可提高牙周炎大鼠眶下神经阻滞麻醉效果
Ekaterina V Blinova,Evgeniia V Shikh,Elena V Semeleva et al.
Ekaterina V Blinova et al.
Background: To evaluate acute toxicity and local anaesthetic activity of a formulation containing a novel dimethylacetamide derivative, antioxidant, and vasoconstrictor in rats with chronic periodontitis. ...
The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ETA Receptor in Mouse Mesenteric Arteries [0.03%]
Ⅲ类PI3K/Beclin-1自噬途径参与mmLDL诱导的小鼠肠系膜动脉ETA受体表达上调
Xi Xie,Chen Chen,Cang-Bao Xu et al.
Xi Xie et al.
Minimally modified low-density lipoprotein (mmLDL) is a risk factor for cardiovascular diseases. The current study explored the effect of mmLDL on the endothelin type A (ETA) receptor in mouse mesenteric arteries in vivo, as well as the rol...
Attitudes, Opportunities, and Challenges for Clinical Pharmacy Services in Mizan-Tepi University Teaching Hospital, Southwest Ethiopia: Health Care Providers' Perspective [0.03%]
从医疗服务提供者角度看埃塞俄比亚西南部米赞-特佩大学教学医院临床药学服务的态度、机会和挑战
Solomon Hambisa,Abebaw Abie,Dejen Nureye et al.
Solomon Hambisa et al.
Background: Clinical pharmacy is a branch of health sciences that focuses more on the patient than on drug product-oriented services to optimize drug therapy. This study aimed to assess attitudes, opportunities, and chall...
Hydroethanolic Stem Bark Extract of Burkea africana Attenuates Vincristine-Induced Peripheral Neuropathy in Rats [0.03%]
Burkea africana的乙醇提取物可减轻vincristine致大鼠外周神经病变
Yakubu Jibira,Eric Boakye-Gyasi,Wonder Kofi Mensah Abotsi et al.
Yakubu Jibira et al.
Context. The stem bark of the savanna tree Burkea africana (Hook) (family: Leguminosae) is used in the Ghanaian traditional medicine for the management of various pain-related diseases. ...
Formulation and Optimization of Monolithic Fixed-Dose Combination of Metformin HCl and Glibenclamide Orodispersible Tablets [0.03%]
盐酸二甲双胍与格列本脲单方固体制剂奥氏分散片的制备及优化
Anteneh Belayneh,Fantahun Molla,Getu Kahsay
Anteneh Belayneh
The treatment of type II DM involves the use of combination of drugs, especially at the chronic stage. However, the pill burden of this combination therapy combined with swallowing difficulties, occurring at a later stage of DM, has been th...
Physiological and Biochemical Vascular Reactivity Parameters of Angiotensin II and the Action of Biased Agonist TRV023 [0.03%]
血管反应性生理和生化参数以及偏向激动剂TRV023的作用机制研究
Marcos André Soares Leal,Thanisia de Almeida,João Guilherme Torres et al.
Marcos André Soares Leal et al.
Vascular reactivity experiments using isolated aortic rings have been widely used as a model for physiological and pharmacological studies since the early sixties. Here, we suggest several parameters that the researcher should pay attention...
Acetylation and Evaluation of Taro Boloso-I Starch as Directly Compressible Excipient in Tablet Formulation [0.03%]
芭蕉Boloso-I淀粉的乙酰化及其作为直接压片辅料性能的研究
Afewerk Getachew,Zewdu Yilma,Solomon Abrha
Afewerk Getachew
Taro Boloso-I (TB1), a newly improved Colocasia esculenta variety, is a potential source of starch with high yield. However, to improve some limitations of the native starches (NS), such as flowability and compactibility, different physical...