Katerina Kanevche,David Joll Burr,Janina Drauschke et al.
Katerina Kanevche et al.
Infrared (IR) nanoscopy represents a collection of imaging and spectroscopy techniques capable of resolving IR absorption on the nanometer scale. Chemical specificity is leveraged from vibrational spectroscopy, while light-matter interactio...
Bengt Nordén
Bengt Nordén
Editorial
QRB discovery. 2026 Jan 5:7:e1. DOI:10.1017/qrd.2025.10017 2026
Victor Rodríguez-Franco,Michelle Marie Spiering,Piero Bianco et al.
Victor Rodríguez-Franco et al.
DNA helicases are molecular motors that use the energy from nucleotide hydrolysis to move along DNA, promoting the unwinding or rewinding of the double helix. Here, we use magnetic and optical tweezers to track the motion of three helicases...
The low complexity linker of DNAJB6b is key to its anti-amyloid function [0.03%]
DNAJB6b的低复杂性链接区域是其抗淀粉样蛋白功能的关键区域
Timas Merkelis,Ulf Olsson,Sara Linse
Timas Merkelis
Neurodegenerative disorders, such as Alzheimer's and Parkinson's diseases, are associated with the formation of amyloid fibrils. The DNAJB6b (JB6) chaperone greatly inhibits the disease-related self-assembly of amyloid peptides in an ATP-in...
On the possibility of carbon-free heteropolymers on Venus: a computational astrobiology study [0.03%]
关于金星上无碳杂聚物的可能性：一项计算古生物学研究
Ishaan Madan,Shekoufeh Arabi Aliabadi,Johanna Huhtasaari et al.
Ishaan Madan et al.
This work poses and partially explores an astrobiological hypothesis: might polymeric sulfur and phosphorus-based oxides form heteropolymers in the acidic cloud decks of Venus' atmosphere? Following an introduction to the emerging field of ...
James W Wells,Tigran V Chalikian
James W Wells
G-quadruplexes and i-motifs are non-canonical secondary structures of DNA that act as conformational switches in controlling genomic events. Within the genome, G- and C-rich sequences with the potential to fold into G-quadruplexes and i-mot...
A workflow to define structural classes and classify nucleic acids circular dichroism spectra [0.03%]
定义结构类别及核酸圆二色谱分类的 workflow
Kevin Mosca,Søren Vrønning Hoffmann,Alice Grangier et al.
Kevin Mosca et al.
Circular dichroism (CD) spectroscopy is a widely utilized technique for studying the structures of chiral molecules, including nucleic acids. It is particularly valued for its ability to quickly probe structural changes in these biomolecule...
Unraveling the nature of physicochemical and biological processes underlying vesicular exocytotic release events through modeling of amperometric current spikes [0.03%]
通过电流脉冲的建模解开物理化学和生物过程的性质以研究胞外囊泡释放事件
Alexander Oleinick,Irina Svir,Christian Amatore
Alexander Oleinick
This work offers a comprehensive approach to understanding the phenomena underlying vesicular exocytosis, a process involved in vital functions of living organisms such as neuronal and neuroendocrine signaling. The kinetics of release of mo...
A structural and functional bioinformatics study of QTY-designed retinylidene proteins [0.03%]
QTY设计的视黄基蛋白的结构与功能生物信息学研究
Siqi Pan
Siqi Pan
Retinylidene proteins are retinal-binding light-sensitive proteins found in organisms ranging from microbes to human. Microbial opsins have been utilized in optogenetics, while animal opsins are essential for vision and light-dependent meta...
Eric Wilson,Akshansh Kaushik,Soumya Dutta et al.
Eric Wilson et al.
Computational immunology has been the breeding ground of some of the best bioinformatics work of the day. By melding diverse data types, these approaches have been successful in associating genotypes with phenotypes. However, the representa...