A Qualitative Investigation of the Experience of Taking Xanomeline and Trospium Chloride for Schizophrenia, Part 1: Perceived Impact on Symptoms [0.03%]
William P Horan,Cory Saucier,Peter J Weiden et al.
William P Horan et al.
Introduction: Xanomeline and trospium chloride (formerly KarXT) is a muscarinic M1 and M4 receptor agonist recently approved for the treatment of schizophrenia in adults. Unlike all previously approved antipsychotics, it ...
Quality of Life After Psychosis: Surviving Schizophrenia and Making a Full Emotional Recovery [0.03%]
精神病后的生命质量：幸存下来的精神分裂症和实现完整的情感康复
Sarah Merritt Ryan
Sarah Merritt Ryan
Sleep Disturbances, Psychosis Symptoms, and Suicidal Ideation in First Episode Psychosis: An Exploratory Mixed-Methods Study [0.03%]
首次精神病发作患者的睡眠障碍、精神分裂症症状及自杀意念的关联：一项探索性混合研究方法的研究
Eva Rogers,Mark Gresswell,Simon Durrant et al.
Eva Rogers et al.
Sleep disturbances are a risk factor for suicidal ideation and are commonly reported amongst individuals experiencing psychosis. Given elevated suicide risk in first episode psychosis (FEP), understanding associations between sleep and suic...
Attitudes Driving Regional Differences in Long-Acting Injectable Antipsychotic Utilization for Schizophrenia among Healthcare Professionals, Patients, and Caregivers (ADVANCE): Results from a Multinational Survey Study [0.03%]
关于精神卫生从业人员、患者和护理人员对长效注射型抗精神病药物用于治疗精神分裂症的态度驱动区域差异的横断面调查研究（ADVANCE）：多国调查结果
Kelli R Franzenburg,Rolf Hansen,Mark Suett et al.
Kelli R Franzenburg et al.
Background: Long-acting injectable (LAI) antipsychotics improve adherence and reduce schizophrenia relapse rates vs oral antipsychotics (OAs) but remain underused. The ADVANCE study explored country-level differences in L...
An Exploratory Study of Inflammatory Biomarkers and Extrapyramidal Side Effects in Patients with Schizophrenia [0.03%]
精神分裂症患者炎症生物标志物和锥体外系不良反应的探索性研究
Naista Zhand,Esther Carefoot,Fatima Iftikhar et al.
Naista Zhand et al.
Background: Extrapyramidal symptoms (EPS) are common side effects of antipsychotic medications and can contribute to medication non-adherence and subsequent relapse in schizophrenia. Recent research suggests that inflamma...
The First Episode Psychosis Services Fidelity Scale as a Measure of Quality of Care [0.03%]
首个发作精神病服务忠实度量表作为衡量护理质量的工具
Su Lynn Tan,Julia Kirkham,Donald Addington
Su Lynn Tan
Background: Fidelity scales are designed to assess the degree to which a program delivers the core components of evidence-based programs. The degree to which scales can predict outcomes-its predictive validity-is an impor...
Baseline Social Functioning Is Associated with Increased Likelihood of Remission from a Clinical High Risk for Psychosis Syndrome [0.03%]
基线社会功能与临床前精神病综合症缓解的相关性研究
Maeve Hoffman,Luz Maria Alliende,Victor Pokorny et al.
Maeve Hoffman et al.
Background and hypothesis: Most individuals at clinical high risk for psychosis (CHR) will not develop psychosis. Moreover, a proportion of individuals who meet the criteria for a CHR syndrome at one time point stop meeti...
Impacts of Polyenvironmental Factors on DNA Methylation in Patients With Psychosis [0.03%]
精神疾病患者的多环境因素对DNA甲基化的影响
Fatima Zahra Rami,Chaeyeong Kang,Ling Li et al.
Fatima Zahra Rami et al.
Background: Only a few studies have investigated the association of environmental factors with DNA methylation in schizophrenia (SZ). Our study sought to investigate differentially methylated positions (DMPs) and differen...
Protective Effects of N-Acetylcysteine Against Schizophrenia-Related Behavioral and Parvalbumin Interneuron Deficits Induced by Adolescent Stress [0.03%]
N乙酰半胱氨酸对青少年期应激诱导的行为及石碳酸蛋白中间神经元缺陷的保护效应研究
Ícaro S Freitas,Francisco S Guimarães,Felipe V Gomes
Ícaro S Freitas
Background and hypothesis: Adolescent stress has been linked to an increased risk of developing psychiatric disorders, including schizophrenia. Previous findings from our group suggest that adolescent stress causes redox ...