The prognostic role of surgical resection in selected patients with primary CNS lymphoma based on voxel-wise analysis [0.03%]
基于体素分析的选择性原发中枢神经系统淋巴瘤患者手术切除的预后作用
Zhangqi Dou,Jiawei Wu,Xianggui Yuan et al.
Zhangqi Dou et al.
Introduction: Surgical resection is controversial in treating primary central nervous system lymphoma (PCNSL). This study aimed to elucidate the prognostic role of resection based on treatment- and survival-related tumor ...
A WEb-Accessible comprehensiVE platform for automatic vestibular schwannoma segmentation and longitudinal volumetric tracking [0.03%]
一种用于web访问的前庭神经鞘瘤分割和纵向体积追踪的自动综合平台
Riya Prashad,Gregory Szalkowski,Jen-Yeu Wang et al.
Riya Prashad et al.
Background: Vestibular schwannomas (VS) require long-term tracking for treatment decisions and outcome assessment. This study aims to develop a WEb-Accessible comprehensiVE (WEAVE) platform that combines AI-driven segment...
A volume-conformity paradoxon: Volumetric determinants of treatment success/failure following stereotactic radiosurgery in vestibular schwannoma [0.03%]
体积一致性悖论：立体定向放射外科手术后前庭神经鞘瘤治疗成功/失败的体积决定因素
Sophie Shih-Yüng Wang,Georgios Naros,Albertus van Eck et al.
Sophie Shih-Yüng Wang et al.
Background: Stereotactic radiosurgery (SRS) is an established, minimally invasive treatment for vestibular schwannoma (VS). However, tumor control rates vary, and predictors of treatment failure remain debated. This study...
Possible involvement of genome-wide near-haploidy and MEN1 mutation in the molecular pathogenesis of pituitary carcinoma: Analysis by whole exome sequencing [0.03%]
全外显子组测序分析提示基因组近单倍体状态和MEN1突变可能参与垂体癌的分子发病机制
Satoru Kida,Takuma Nakashima,Satoshi Baba et al.
Satoru Kida et al.
Background: Pituitary carcinoma is a rare tumor, accounting for 0.12% of pituitary neuroendocrine tumors (PitNETs), that is derived from adenohypophyseal cells with craniospinal or systemic metastasis. While most PitNETs ...
Long-term outcomes and late complications of intracranial germinoma: Implications for follow-up policy [0.03%]
颅内生殖细胞瘤的长期预后及晚期并发症与随访策略的意义
Youngbo Shim,Seung-Ki Kim,Kyung Hyun Kim et al.
Youngbo Shim et al.
Background: We retrospectively assessed the long-term efficacy, safety, and functional outcome of chemotherapy and radiotherapy (RT) in patients with intracranial germinoma (iGE). ...
Sonobiopsy for enrichment of circulating microRNAs in glioma patients [0.03%]
用于胶质瘤患者循环microRNA富集的sono biopsy技术研究
Jinyun Yuan,Yuanxiang Li,Chih-Yen Chien et al.
Jinyun Yuan et al.
Background: Sonobiopsy is a promising new technique that employs focused ultrasound (FUS) to noninvasively enrich brain tumor-derived biomarkers from spatially targeted brain location into the bloodstream. Building upon o...
Sensitivity and specificity of cerebrospinal fluid placental alkaline phosphatase in germinoma: An 8 pg/mL threshold [0.03%]
脑脊液胎盘碱性磷酸酶在生殖细胞瘤中的敏感性和特异性：8pg/ml阈值
Kentaro Chiba,Yasuo Aihara,Yuichi Oda et al.
Kentaro Chiba et al.
Background: Cerebrospinal fluid placental alkaline phosphatase (CSF-PLAP) is useful in diagnosing intracranial germinomas. However, reports on CSF-PLAP in histological subtypes other than germinoma remain limited. The pri...
Exploring brain-glioma interaction: Effect of neuroligin-3 expression on neurocognitive functioning is independent from epilepsy [0.03%]
探索脑胶质瘤相互作用：神经突触蛋白-3的表达对神经认知功能的影响独立于癫痫而存在
Eva A Krijnen,Emma van Kessel,Angelika Mühlebner et al.
Eva A Krijnen et al.
Background: Neurocognitive deficits are common in patients with diffuse glioma, compromising quality of life and prognosis. Neuroligin-3 is a postsynaptic activity-dependent protein, considered a key component of brain-gl...
Explainable machine learning/artificial intelligence model for estimating postoperative survival in renal cell carcinoma brain metastasis patients [0.03%]
用于估计肾细胞癌脑转移患者术后生存率的可解释机器学习/人工智能模型
Zuhair Majeed,Semiha Ozgul,Peng Li et al.
Zuhair Majeed et al.
Background: Brain metastases (BM) from renal cell carcinoma (RCC) are associated with poor prognosis and limited survival. Prognostic tools specific to patients with RCC undergoing surgical resection of BM are lacking, an...
Pharmacologic inhibition of RBBP4/p300-mediated homologous recombination activity enhances glioblastoma sensitivity to temozolomide [0.03%]
药理学抑制RBBP4/p300介导的同源重组活性可增强胶质母细胞瘤对替莫唑胺的敏感性
Josephine A Mapunda,Daniel J Laverty,Faisal Aziz et al.
Josephine A Mapunda et al.
Background: Upstream regulators of the homologous recombination (HR) repair pathway are promising targets for overcoming temozolomide (TMZ) resistance. We investigated whether pharmacologic inhibition of Retinoblastoma Bi...