Artificial intelligence-based volumetric measurements for longitudinal clinical assessment of treatment response in high-grade gliomas: Validation across institutional and public datasets [0.03%]
Zerubabbel K Asfaw,Tirone Young,Gianina Hernandez Marquez et al.
Zerubabbel K Asfaw et al.
Background: High-grade gliomas (HGGs) require ongoing imaging to guide treatment, traditionally relying on labor-intensive and variable manual MRI measurements. While FDA-cleared artificial intelligence (AI) tools offer a...
Julian Canisius,Josef Buchner,Marcel Rosier et al.
Julian Canisius et al.
Background: Precise glioma segmentation in magnetic resonance imaging (MRI) is essential for accurate diagnosis, optimal treatment planning, and advancing clinical research. However, most deep learning approaches require ...
Volumetric MRI-based response assessment and prognostic value in newly diagnosed glioblastoma: RANO 2.0 versus mRANO versus RANO [0.03%]
基于体积的磁共振成像反应评估和新诊断胶质母细胞瘤的预后价值：RANO 2.0 vs mRANO vs RANO标准
Johanna Heugenhauser,Wolfgang Orth,Manuel Sarcletti et al.
Johanna Heugenhauser et al.
Background: This retrospective study used volumetric MRI assessment to compare 3 response assessment criteria, namely, RANO (response assessment in neuro-oncology), mRANO (modified response assessment in neuro-oncology), ...
Epigenetic buffering of proteotoxic stress by EHMT2 enables meningioma growth [0.03%]
组蛋白甲基转移酶EHMT2通过表观遗传缓冲蛋白毒性压力促进脑膜瘤生长
Bethany C Berry,Tomas Rodriguez,Connie C Hou et al.
Bethany C Berry et al.
Background: Aggressive meningiomas often display chromosomal abnormalities disrupting more than 20% of the genome, but the mechanisms that allow meningioma cells to thrive nevertheless are unknown. ...
Treatment initiation by positive liquid biopsy alone in primary central nervous system lymphoma: A retrospective analysis of a multi-institutional study [0.03%]
基于液体活检阳性结果启动初治原发中枢神经系统淋巴瘤治疗的多中心回顾性分析研究
Masaki Mitobe,Satoshi Shibuma,Haruhiko Takahashi et al.
Masaki Mitobe et al.
Background: The gold standard for the diagnosis of primary central nervous system lymphoma (PCNSL) remains surgical biopsy, but it carries the risk of complications, and operability depends on the size and location of the...
Perioperative neurocognitive functioning in elderly patients undergoing awake craniotomy for high grade glioma [0.03%]
高分级胶质瘤患者清醒开颅术围手术期神经认知功能损伤
Eric A Goethe,Kyle R Noll,Subhiksha Srinivasan et al.
Eric A Goethe et al.
Introduction: Older patients may be at particular risk of decline in neurocognitive function (NCF) following brain tumor resection, particularly when tumors are near-eloquent regions. ...
Focused ultrasound for blood-brain barrier opening in brain tumor patients: Technical nuances [0.03%]
聚焦超声技术在胶质瘤患者中的应用及注意事项：血脑屏障打开
Massimiliano Del Bene,Valentina Caldiera,Mario Stanziano et al.
Massimiliano Del Bene et al.
Introduction: Focused ultrasound (FUS) is making rapid advances in the field of neurological sciences. While proven effective for tremor, pain and dystonia, FUS hold promises in experimental applications like blood-brain ...
Drawing parallels between amyloid PET in Alzheimer's disease and amino acid PET in primary and secondary brain tumors [0.03%]
阿尔茨海默病淀粉样PET与原发性和继发性脑肿瘤氨基酸PET的比较分析
Nelleke Tolboom,Antoine Verger,Matthias Preusser et al.
Nelleke Tolboom et al.
The evolution of amyloid PET in Alzheimer's disease illustrates the potential path of amino acid PET in neuro-oncology. Initially seen as of limited value, amyloid PET ultimately enhanced diagnostic accuracy, guided management, and became c...
Artificial intelligence pipeline predicts the integrated molecular-morphologic risk score of meningiomas from routine preoperative MRI [0.03%]
基于常规术前MRI预测脑膜瘤综合分子-形态学风险评分的智能算法模型
Damjan Veljanoski,Ali Golbaf,Prutha Chawda et al.
Damjan Veljanoski et al.
Background: Meningiomas are the most common primary intracranial neoplasms. A significant unmet need exists for noninvasive biomarkers to risk-stratify patients and guide decision-making. The integrated risk score (IRS), ...
BRAF-mutant high-grade glioma with pleomorphic and pseudopapillary features (HPAP): A PLNTY mimic demonstrating tumor progression during longitudinal follow-up [0.03%]
具有多形性和假小叶特征的BRAF突变型高级别胶质瘤（HPAP）：在纵向随访期间表现出肿瘤进展的PLNTY样病变
Yutaro Takayama,Mariko Yaegashi,Kaishi Satomi et al.
Yutaro Takayama et al.
Background: High-grade glioma with pleomorphic and pseudopapillary features (HPAP) is a recently recognized glioma subtype defined by DNA methylation profiling. While it exhibits overlapping histological features with var...