Intracerebral hemorrhage risk in glioma patients taking direct oral anticoagulants as compared with low molecular weight heparin [0.03%]
直接口服抗凝药物与低分子肝素治疗胶质瘤患者的脑内出血风险比较
Radhika S Amin,Scott Cameron,Matthew M Grabowski et al.
Radhika S Amin et al.
Abstract: BackgroundGlioma patients may require long-term anticoagulation for comorbidities, including arrhythmias or venous thromboembolism (VTE). While direct oral anticoagulants (DOACs) have demonstrated safety in gene...
New biomarkers for the diagnosis of primary central nervous system lymphoma in CSF: A multicenter retrospective cohort study [0.03%]
脑脊液中初发中枢神经系统淋巴瘤诊断新生物标志物的多中心回顾性队列研究
Josephus L M van Rooij,Peter H Wessels,Eveline M Delemarre et al.
Josephus L M van Rooij et al.
Background: Primary central nervous system lymphoma (PCNSL) is a rare form of non-Hodgkin lymphoma. Diagnosis usually requires a brain biopsy, which is associated with complications and delay of diagnosis. Cerebrospinal f...
Dose-enhanced versus standard TTFields for first recurrence of glioblastoma: A randomized phase 2 clinical trial [0.03%]
高强度与标准强度肿瘤治疗电场复发胶质母细胞瘤患者的疗效比较：随机II期临床试验
Nikola Mikic,Slávka Lukacova,Jane Skjøth-Rasmussen et al.
Nikola Mikic et al.
Abstract: BackgroundStudies suggest that high intensities of tumor treating fields (TTFields) correlate with prolonged survival in newly diagnosed glioblastoma. However, no randomized clinical studies have tested differen...
LCLAT1 regulates cardiolipin composition, mitochondrial phenotype, Lin28A, and oncogenic signaling networks in ETMR [0.03%]
LCLAT1调节ETMR中的卵黄索脂质组成、线粒体表型、Lin28A和致癌信号网络
Evangelos Liapis,Allison Maas,Kelly C O&#x;Neill et al.
Evangelos Liapis et al.
Abstract: BackgroundEmbryonal tumor with multilayered rosettes (ETMR) is an aggressive pediatric brain tumor that carries a poor prognosis, and there is currently no standard of care. Dysregulated mitochondrial bioenerget...
Combined subtotal resection and stereotactic radiosurgery for large vestibular schwannomas: A systematic review and meta-analysis [0.03%]
大型听神经瘤的次全切除联合立体定向放射外科手术的系统评价和meta分析
Shahin Naghizadeh,Maryam Zohrabi-Fard,Amir-Ahmad Keramati et al.
Shahin Naghizadeh et al.
Background: Large vestibular schwannomas (VSs), particularly Koos grade III-IV, often require a balance between tumor control and cranial nerve preservation. This meta-analysis evaluates outcomes of planned subtotal or ne...
Artificial intelligence-based analysis and diagnosis of intradural extramedullary spinal tumors by stimulated Raman histology [0.03%]
基于人工智能的刺激拉曼组织学分析和诊断脊髓髓内肿瘤
Pierre Scheffler,Nicolas Neidert,Jakob Straehle et al.
Pierre Scheffler et al.
Background: Intraoperative Stimulated Raman Histology (SRH) has been reported to be fast and accurate in the assessment of neuro-oncological lesions. However, its application to spinal tumors, especially intradural extram...
H3K27M- and BRAF V600E-Altered gliomas and glioneuronal tumors-clinico-pathologic and radiologic perspective in a cohort treated with targeted therapy [0.03%]
H3K27M和BRAF V600E基因突变型胶质瘤及胶质神经肿瘤的临床病理学及影像学特征——靶向治疗病例队列分析
Carolyn G Chen,Vanessa Rameh,Tom Rosenberg et al.
Carolyn G Chen et al.
Background: Among diffuse midline gliomas with H3K27-altered with MAPK pathway mutations, those with BRAF V600E mutations show the most histologic variability and potential for targeted therapy, yet remain incompletely ch...
"Oh my word, so overwhelmed": Exploring the patient and family experience with diagnosis and treatment decision-making in pediatric CNS tumors [0.03%]
“天啊，我应付不来”：儿科中枢神经系统肿瘤患者及家属在诊断和治疗决策中的体验探究
Gabrielle Helton,Will Daley,Gianni Solis et al.
Gabrielle Helton et al.
Background: Pediatric central nervous system (CNS) tumors are the leading cause of cancer-related mortality in children, with survival outcomes significantly influenced by racial, ethnic, and socioeconomic disparities. Th...
DIAPH3 is upregulated in high-grade gliomas and linked to chromosomal instability [0.03%]
DIAPH3在高级别胶质瘤中过度表达并引起染色体不稳定
Caren Jabbour,Mathilde Beka,Philippe Gailly et al.
Caren Jabbour et al.
Abstract: BackgroundDiaphanous-related formin 3 (DIAPH3) is a member of the formin family, a group of proteins that regulate actin and microtubule dynamics. During mitosis, DIAPH3 localizes specifically to the centrosome....
Assessment of 18F-FET PET-based response in patients with gliomas using the PET RANO 1.0 criteria [0.03%]
基于PET RANO 1.0标准评价胶质瘤患者的18F-FET PET疗效
Garry Ceccon,Michael Wollring,Isabelle Stetter et al.
Garry Ceccon et al.
Background: We evaluated the amino acid PET-based response assessment criteria (PET RANO 1.0) for their proficiency in predicting longer survival in patients with gliomas undergoing adjuvant temozolomide chemotherapy. ...