Performance of a clinical decision-support tool on empirical antibiotic treatment in the emergency department: a retrospective study [0.03%]
急诊临床抗生素经验性治疗决策支持系统绩效的回顾性研究
Sara N Søgaard,Logan Ward,Mads Lause Mogensen et al.
Sara N Søgaard et al.
Background and objectives: Antimicrobial resistance remains a global health challenge despite the WHO AWaRe framework promoting responsible antibiotic use. Adherence to clinical guidelines, particularly during initial emp...
Optimizing intravenous amoxicillin for outpatient parenteral antimicrobial therapy [0.03%]
门诊患者输注抗生素治疗的氨苄西林优化剂量研究
Zenaw T Wolie,Jason A Roberts,Steven C Wallis et al.
Zenaw T Wolie et al.
Background and objectives: Poor aqueous stability limits the use of continuous infusion of intravenous (IV) amoxicillin in outpatient parenteral antimicrobial therapy. This study aimed to evaluate whether buffering improv...
Carbapenemase type-dependent pharmacodynamic activity of minocycline-biapenem combination against carbapenemase-producing Klebsiella pneumoniae [0.03%]
美罗培南米诺环素联合用药对碳青霉烯耐药肺炎克雷伯菌的药动学活性受酶型影响
Takashi Okanda,Niinyo Nakajima,Tetsuo Yamaguchi et al.
Takashi Okanda et al.
Objectives: The activity of antimicrobial combinations against carbapenemase-producing Klebsiella pneumoniae (CPKP) is likely to depend on the underlying resistance mechanism; however, this has not been systematically eva...
Emergence of carbapenemase KPC-14 in an Escherichia coli isolate: a case report [0.03%]
一起产KPC-14碳青霉烯酶大肠埃希菌的病例报道
Leticia Fontán García-Rodrigo,María Díez Aguilar,Laura Sevillano Tripero et al.
Leticia Fontán García-Rodrigo et al.
Emergence of Trichophyton indotineae: in vitro susceptibility data from a mycology reference laboratory in Australia [0.03%]
特比萘芬(indotineae)的出现：澳大利亚一家真菌学参考实验室的体外敏感性数据
Maryam Roudbary,Sharon C A Chen,Ana Vieira da Silva et al.
Maryam Roudbary et al.
Background: Management of Trichophyton indotineae dermatophytosis is challenged by high terbinafine resistance rates within this species. Antifungal susceptibility data for Australian T. indotineae isolates are lacking. H...
Penicillin allergy de-labelling in primary care; correcting primary care records using a prescribing incentive scheme in Cornwall [0.03%]
青霉素过敏解除标注项目：通过开处方的奖励方案更正康沃尔地区的全科医生记录
Neil Powell,Michael Wilcock,Paige Rickard et al.
Neil Powell et al.
Introduction: Penicillin allergy records are common and associated with several patient and health system harms. Using the local primary care prescribing and medicines optimization scheme (PMOS) for 2025/26 GP practices w...
Molecular epidemiology and antimicrobial resistance of extended-spectrum beta-lactamases-producing Enterobacter cloacae complex among mothers, neonates, healthcare workers and hospital environments in Tanga, Tanzania [0.03%]
坦桑尼亚塔נגר斯中产妇、新生儿、医务人员和医院环境中的产超广谱β内酰胺酶肠杆菌复合群的分子流行病学及耐药性研究
Athanas D Mhina,Neyaz A Khan,Ricardo Strauss et al.
Athanas D Mhina et al.
Background: The Enterobacter cloacae complex (ECC) is an emerging healthcare-associated pathogen and an increasing cause of infections in neonatal intensive care units. Its clinical relevance is driven by the rapid acquis...
Giusy Tiseo,Valentina Galfo,Marco Falcone
Giusy Tiseo
MRSA remains a major global health challenge. Although its global prevalence has declined over the last decade, especially in high-income countries, MRSA still has a high burden of invasive infections and mortality. The global epidemiology ...
PCR-based syndromic tests for antibiotic stewardship in non-ventilated patients with hospital-acquired pneumonia: a multicentre randomized controlled trial [0.03%]
基于PCR的抗生素管理方案在非呼吸机支持的医院获得性肺炎患者中的应用：多中心随机对照试验
S Kernéis,E Canouï,L Deconinck et al.
S Kernéis et al.
Objectives: To evaluate whether syndromic multiplex PCR (mPCR) with expert guidance improves antibiotic stewardship in patients with hospital-acquired pneumonia (HAP). ...
MYcology Stewardship Tool (MyST): a retrospective, descriptive multidisciplinary team review of antifungal prescribing practice in a UK tertiary centre [0.03%]
一种针对英国三级医疗中心抗真菌药物处方实践的回顾性、描述性的多学科团队评估工具(MYST)
Bee Yean Ng,Louise Dunsmure,Julie Richards et al.
Bee Yean Ng et al.
Background: Antifungal stewardship (AFS) is essential to managing antimicrobial resistance (AMR), yet remains less well established than antibacterial stewardship. This project aimed to support development of an AFS progr...