Challenges and drivers in the implementation of current practices in outpatient parenteral antimicrobial therapy: an international survey [0.03%]
Solomon Ahmed Mohammed,Jason A Roberts,David Nicolás et al.
Solomon Ahmed Mohammed et al.
Background: Outpatient parenteral antimicrobial therapy (OPAT) is practised worldwide due to the benefits it provides to patients and healthcare systems. However, its full potential remains unrealized due to different imp...
Fpr1p mediates the synergistic effect of rapamycin or tacrolimus with caspofungin in Clavispora lusitaniae in vitro [0.03%]
雷帕霉素或他克莫司与卡波芬净体外协同作用于念珠白南非菌的机制研究：Fpr1p介导的作用效应
Maxime Lefranc,Isabelle Accoceberry,Valérie Fitton-Ouhabi et al.
Maxime Lefranc et al.
Objectives: Caspofungin is an echinocandin antifungal agent that inhibits glucan synthesis, an essential component of the fungal cell wall. Rapamycin and tacrolimus are immunosuppressant drugs that share the same cellular...
S Peter Borriello
S Peter Borriello
Callum Joyce,Saba Anwar,Charlotte Hind et al.
Callum Joyce et al.
Bacterial heteroresistance is defined when a seemingly susceptible population of bacteria contains one or more resistant subpopulations. This behaviour has been seen in a variety of bacteria and with many different antibiotics. Heteroresist...
Evaluation of three variants of the carbapenem inactivation method for carbapenemase detection in Enterobacterales and description of the cCIM, supplemented with cloxacillin [0.03%]
三种碳青霉烯酶失活法（CIM）在肠杆菌目中检测碳青霉烯酶的效果评价及克洛扎霉素补充的cCIM试验描述
Julia Abels,Jessica Eisfeld,Jennifer Pienkoß et al.
Julia Abels et al.
Objectives: To determine which of the three following phenotypic tests is the most suitable for the detection of carbapenemases in Enterobacterales: the modified carbapenem inactivation method (mCIM), zCIM (carbapenem ina...
Empowering researchers and healthcare professionals in academic publishing: key insights and practical lessons from the British Society of Antimicrobial Chemotherapy (BSAC) workshop 2025 [0.03%]
助力学术出版领域的研究人员和医疗专业人员：英国抗菌化疗协会（BSAC）工作坊2025年关键见解与实用经验教训
Godwin Pius Ohemu,Tsitsi Arikana Mufunde,Tracie Muraya et al.
Godwin Pius Ohemu et al.
The British Society of Antimicrobial Chemotherapy (BSAC) Academic Publishing Workshop, held at the Birmingham City Event Centre in the UK from 19 to 20 March 2025, provided practical guidance for early-career researchers and healthcare prof...
Over-the-counter sales of high-priority antibiotics are common: results of a global survey [0.03%]
优先抗生素的非处方销售很常见：一项全球调查的结果
Nkuchia M M&#x;ikanatha,Xin Yin,Katia Iskander et al.
Nkuchia M M&#x;ikanatha et al.
Background: Antimicrobial resistance (AMR) is a critical public health threat exacerbated by the sales of antibiotics without prescriptions. Despite national action plans, data on global over-the-counter (OTC) availabilit...
Appropriateness and determinants of outpatient antibiotic use among migrants in British Columbia, Canada: a population-based study [0.03%]
加拿大不列颠哥伦比亚省移民门诊抗生素使用的适宜性及影响因素的基于人群的研究
Chia-Yuan Chang,Erica Chuang,Deva Thiruchelvam et al.
Chia-Yuan Chang et al.
Background: Migrants represent a diverse population whose unique experiences and healthcare barriers may influence antibiotic prescribing. This study examined the appropriateness of outpatient antibiotic prescriptions and...
Therapeutic strategies for multi-resistant Escherichia coli in urinary tract infections-a cause for concern [0.03%]
应对泌尿道感染的多重耐药大肠杆菌的治疗策略——令人担忧的问题
Rekha Unni,Ruby Varghese,Benita Arakal et al.
Rekha Unni et al.
Antimicrobial resistance (AMR) is a serious and growing public health concern driven by multiple factors. Urinary tract infection (UTI) is one of the infections commonly associated with AMR, and more than 80% of UTIs are caused by Escherich...
Emergence of ST383 carbapenem-resistant Klebsiella pneumoniae harbouring bla NDM-5 and bla OXA-48 carbapenemase genes in a Romanian tertiary-care hospital [0.03%]
blaNDM-5和blaOXA-48碳青霉烯耐药基因导致的ST383肺炎克雷伯菌在罗马尼亚一家三级医院中出现
Valeriu Gheorghiță,Ana Dobrin,Violeta Melinte et al.
Valeriu Gheorghiță et al.
Background: Klebsiella pneumoniae is a major cause of healthcare-associated infections in Romania, where carbapenem resistance rates exceed 63%. The dissemination of clones co-producing multiple carbapenemases poses a cri...