Effect of prophylactic antibiotics on days of antibiotic spectrum coverage in comatose post-cardiac arrest patients: a secondary analysis of PROTECT [0.03%]
预防性抗生素对心脏骤停后昏迷患者的抗菌素使用天数的影响：PROTECT试验的二次分析结果
Alexandra J Weissman,David J Gagnon,Kristin M Burkholder et al.
Alexandra J Weissman et al.
Background: Antibiotic resistance is a threat to public health driven in part by widespread antibiotic administration. Days of antibiotic spectrum coverage (DASC) is a novel metric to quantify both duration and breadth of...
Genetic and clinical landscape of methicillin-resistant Staphylococcus aureus isolates lacking the mec gene, in Japan [0.03%]
日本耐甲氧西林金黄色葡萄球菌株系中缺乏mec基因的菌株的基因组和临床特征分布研究
Tatsuya Natori,Yukiko Nagano,Tomohiro Denda et al.
Tatsuya Natori et al.
Objectives: The present study examines methicillin-resistant Staphylococcus aureus isolates lacking mec (MRLM) phenotypic and genotypic traits and clinical features of patients. ...
Risk factors for carbapenem-resistant Acinetobacter baumannii (CRAB) infections in critically ill patients with previous CRAB colonization: a multicentre cohort study [0.03%]
既往携带碳青霉烯耐药不动杆菌(CRAB)的重症患者中发生CRAB感染的风险因素：一项多中心队列研究
Francesco Cogliati Dezza,Belén Gutiérrez-Gutiérrez,Giusy Tiseo et al.
Francesco Cogliati Dezza et al.
Background: Among MDR bacteria, carbapenem-resistant Acinetobacter baumannii (CRAB) is a major concern due to the limited therapeutic options. Objectives:...
Building antimicrobial stewardship capacity through participatory health literacy workshops in Zimbabwe [0.03%]
通过参与式健康素养工作坊在津巴布韦建立抗菌药物管理能力
Martin Mickelsson,Tungamirirai Simbini
Martin Mickelsson
Background and objectives: Antimicrobial resistance (AMR) poses a mounting sustainability challenge to healthcare systems, especially in Southern African settings, where antimicrobial stewardship capacity is limited by re...
Activity of novel antibiotics against dual metallo-Beta-lactamase producing Enterobacter hormaechei clinical isolates [0.03%]
新抗生素对产双金属β-内酰胺酶肠杆菌临床分离株的活性
Camila Solar,Lorena Diaz,Katherine Soto et al.
Camila Solar et al.
Background: Metallo-β-lactamase (MBL)-producing carbapenemase-resistant Enterobacterales infections are associated with significant mortality. Several β-lactam/β-lactamase inhibitor combinations (BL/BLI) with promising...
Activity of cefepime/enmetazobactam against highly multidrug-resistant bacterial isolates recovered from war-associated wounds in Ukraine [0.03%]
乌克兰战争伤员伤口分离的多重耐药细菌株的培南/恩美培酶的活性
Jale Boral,Nora Toft,Alp Eren Baybes et al.
Jale Boral et al.
Background: Escalating resistance among Gram-negative pathogens limits β-lactam options. Cefepime/enmetazobactam combines a fourth-generation cephalosporin with a class A β-lactamase inhibitor. We evaluated its activity...
A full educational resource review of grey literature resources for vancomycin dosing tutorials [0.03%]
万古霉素给药教程的灰文献资源全面教育性评价
Emma S Kuska,Jen Mlyniec,Kathleen L Wantuch et al.
Emma S Kuska et al.
Background: Optimized vancomycin dosing is associated with improved clinical outcomes, especially decreased acute kidney injury. Free, online, grey literature training materials are available for vancomycin dosing; howeve...
Daniel J Noel,Alistair Bailey,Benjamin I Nicholas et al.
Daniel J Noel et al.
Objectives: Chemical disinfectants are critical for infection control in healthcare environments and beyond, as exemplified by their vital role during the COVID-19 pandemic. Despite research repeatedly demonstrating that ...
Knowledge mobilization and assessment of implementation of an updated national antimicrobial prescribing and stewardship competency framework [0.03%]
抗菌药物处方和管理胜任力框架的更新、实施及评估
Rachel Berry,Tanya Miah,Maria Nasim et al.
Rachel Berry et al.
Background: An Antimicrobial Prescribing and Stewardship (APS) Competency Framework is an important resource for enhancing the practice of prescribers, in-line with national and global priorities for tackling antimicrobia...
Management of infections caused by carbapenemase-producing Enterobacterales in France: a real-world study [0.03%]
法国由产生碳青霉烯酶的肠杆菌科细菌引起感染的管理：一项真实世界研究
B Pilmis,L Escaut,M Seguret et al.
B Pilmis et al.
Background: Carbapenemase-producing Enterobacterales (CPE) are a significant public health concern, with limited treatment options and high mortality rates. The epidemiology and management of CPE infections in France rema...