Immunometabolic Modulation of the Bone Marrow Niche by Bioactive Materials to Rescue Impaired Fracture Healing [0.03%]
生物活性材料通过免疫代谢调节骨髓生态位以治疗骨折愈合障碍
Dong Li,Shaolong Ma
Dong Li
Despite advancements in mechanical fixation, impaired fracture healing remains a significant clinical challenge, largely driven by immunometabolic dysregulation within the bone marrow niche. Conditions such as prolonged M1 macrophage activa...
Oxygen-generating Microparticles Enhance Viability and Functionality of Human Pluripotent Stem Cell-derived Cardiomyocytes for Myocardial Infarction Therapy [0.03%]
生成氧气的微颗粒增强多能干细胞源性心肌细胞缺血治疗有效性的功能和存活率
Xingyu He,Suchandrima Dutta,Darshini Desai et al.
Xingyu He et al.
Background: Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) represent a promising therapy for myocardial infarction (MI), but their survival is severely limited by the hypoxic infarct environment. T...
Amniotic Fluid Stem Cells in Birth Defects: Integrated Roles in Disease Modeling, Prenatal Diagnosis, and Therapy [0.03%]
羊水干细胞在出生缺陷中的作用：疾病建模、产前诊断和治疗的综合角色
Yuanhang Zhu,Xinyue Zhao,Zhongchen Hou et al.
Yuanhang Zhu et al.
Birth defects impose a significant global health burden, driving an urgent need for improved prenatal diagnostic and therapeutic strategies. Amniotic fluid stem cells (AFSCs) have emerged as a uniquely advantageous cell source in this conte...
Induced Pluripotent Stem Cell-Derived NK Cells as an Off-the-Shelf Platform for Cancer Immunotherapy: Opportunities, Challenges, and Clinical Translation [0.03%]
基于诱导多能干细胞的NK细胞作为癌症免疫治疗的即用型平台：机遇、挑战及临床转化
Shiva Mosadegh Manshadi,Maryam Mehravar,Abbas Hajifathali et al.
Shiva Mosadegh Manshadi et al.
In recent years, off-the-shelf cellular immunotherapies have attracted much attention as a practical alternative to autologous therapies. Within this landscape, induced pluripotent stem cell-derived natural killer cells (iPSC-derived NK cel...
Stem Cell-based Therapeutic and Endogenous Regeneration Approaches for Congenital Tooth Agenesis [0.03%]
基于干细胞的治疗和内源性再生方法用于先天性牙齿发育不全
Pierre-Yves Collart-Dutilleul,Damien Veret,Richard Younes et al.
Pierre-Yves Collart-Dutilleul et al.
Congenital tooth agenesis, including hypodontia and oligodontia, represents one of the most common developmental anomalies of the craniofacial complex and reflects failure of odontogenesis rather than postnatal tissue degeneration. The abse...
Correction: Omentum-Derived Mesenchymal Stem Cells Promote Antibacterial Effects and Protect Endothelial Functions via PAI-1 [0.03%]
纠正：腹膜来源的间充质干细胞通过PAI-1促进抗菌作用并保护内皮功能
Adeline Castro Ramos,Cat-Khanh Vuong,Mizuho Fukushige et al.
Adeline Castro Ramos et al.
Published Erratum
Stem cell reviews and reports. 2026 May 12. DOI:10.1007/s12015-026-11152-2 2026
iPSC-Derived 3D Brain Organoids as Next-generation Platforms to Study Viral and Toxicant-associated Neurodegeneration [0.03%]
基于 iPSC 的 3D 脑器官体作为研究病毒和毒物相关神经退行性疾病的下一代平台
Md Shahadab,Vaishali Saini,Siddharth Singh et al.
Md Shahadab et al.
Neurodegenerative diseases (ND) are one of the most fatal diseases that affect the majority of individuals worldwide, among which Alzheimer's disease (AD) and Parkinson's disease (PD) are the most common. In vitro 2D monolayer cell cultures...
Bone Marrow Mesenchymal Stem Cell Extracellular Vesicle Treatment of Respiratory Failure from COVID-19: Endpoint Analysis of Expanded Access Safety Trial [0.03%]
骨髓间充质干细胞胞外囊泡治疗COVID-19呼吸衰竭的安全性拓展研究终点分析
Vikram Sengupta,Sascha Qian,John T Ransom et al.
Vikram Sengupta et al.
The safety of an extracellular vesicle (EV) enriched secretome from bone marrow mesenchymal stem cells (BM-MSCs) was evaluated in a multi-site, prospective, expanded access trial as potential treatment for respiratory failure due to COVID-1...
Priming of Mesenchymal Stem Cells for Tendon Regeneration: Mechanisms and Clinical Translation [0.03%]
用于肌腱再生的间充质干细胞启动：机制及临床转化
Ki-Bong Park,Hasung Park,Young Dae Jeon
Ki-Bong Park
Rotator cuff tears remain a major cause of shoulder dysfunction; however, retears and incomplete healing persist despite advances in surgical repair. Conventional techniques fail to restore the native tendon-bone interface, resulting in mec...
"Hair Follicle Stem Cells and their Lymphatic Niche: An Overlooked Axis in Cutaneous Regeneration" [0.03%]
"毛囊干细胞及其淋巴微环境：一个被忽视的皮肤再生轴"
Rinky Kapoor,Varad Rajendra Saptarshi,Raji Patil et al.
Rinky Kapoor et al.