Effects Of Oxygen Tension On iPSC Morphology And Small Extracellular Vesicle Particle Characteristics [0.03%]
氧张力对诱导多能干细胞形态和小型细胞外囊泡颗粒特性的影响
Siti Zawiah Abdul Malik,Siti A M Imran,Min Hwei Ng et al.
Siti Zawiah Abdul Malik et al.
Gasdermin A3 Drives Hair Graying via Ectopic Melanocyte Stem Cell Differentiation and Migration [0.03%]
Gasdermin A3通过异常黑素干细胞分化和迁移驱动头发变白
Haiying Guo,Xiufeng Bai,Hao Gong et al.
Haiying Guo et al.
Yumeng Lin,Yuchen He,Quan Yuan et al.
Yumeng Lin et al.
Bone repair is a complex regenerative process involving inflammatory responses, vascular remodeling, and stem cell-mediated osteogenesis, wherein the immune microenvironment plays a critical regulatory role. Neutrophils have long been recog...
DMBT1 in Adipose-Derived Stem Cell-Derived Exosomes Participates in Alleviating Ferroptosis to Promote Diabetic Wound Healing [0.03%]
来源于脂肪间充质干细胞外泌体的DMBT1通过缓解铁死亡促进糖尿病创面修复
Yan Liu,Jinnan Wang,Yujiao Cai et al.
Yan Liu et al.
Diabetic wounds represent one of the most severe complications of diabetes, and their clinical management remains challenging. This study investigated the therapeutic potential of adipose-derived stem cell-derived exosomes (ADSCs-Exo) for d...
Harnessing Endogenous Plasticity Rather than Reprogramming of Mature Cells Will Advance Regenerative Medicine, Cancer Treatment and Rejuvenation [0.03%]
利用内在细胞重编而非对成熟细胞去编程能推进再生医疗、癌症治疗及恢复青春的研究工作
Deepa Bhartiya,Nripen Sharma,Anish Tripathi et al.
Deepa Bhartiya et al.
The successful culture of human embryonic stem (hES) cells from inner cell mass cells of blastocyst stage 'spare' embryos in 1998, followed by induced pluripotent stem (iPS) cells in 2006, which allowed somatic cells to be reprogrammed to p...
Hair Follicle Stem Cells: Emerging Physiology and Therapeutic Applications [0.03%]
毛囊干细胞：新兴的生理学和治疗应用
Shuyuan Yang,Qun Chen,Hanluo Li et al.
Shuyuan Yang et al.
Hair follicle stem cells (HFSCs) have been studied for their role in developmental biology, hair cycling and transplantation. However, recent research reframes the hair follicle as a heterogeneous regenerative ecosystem capable of respondin...
Cell Therapy as Metabolic Rescue after Ischemic Stroke: Rewiring Bioenergetics, Redox Homeostasis, and Neurovascular Repair [0.03%]
细胞治疗在缺血性卒中后的代谢救援：重塑生物能量、氧化还原平衡及神经血管修复
Salar Bakhtiyari,Iraj Alipourfard
Salar Bakhtiyari
Ischemic stroke represents a dynamic metabolic disorder of the neurovascular unit (NVU) rather than a static vascular occlusion followed by neuronal demise. Immediate oxygen and glucose deprivation rapidly deplete ATP, disrupt the transmemb...
Nanotechnology-enabled precision targeting of lung cancer stem cells: Recent developments and therapeutic implications [0.03%]
纳米技术在肺癌干细胞精准靶向中的新进展及治疗意义
Yi Zhang,Jiaxin Fan,Yuhan Ye et al.
Yi Zhang et al.
Lung cancer remains one of the leading causes of cancer-related mortality worldwide, highlighting the urgent need for more effective therapeutic strategies. Lung cancer stem cells (LCSCs) play critical roles in tumor initiation, metastasis,...
Measurable Residual Disease and the Unresolved Biology of Leukemic Stem Cells [0.03%]
可测量的残留疾病和白血病干细胞未解决的生物学问题
Deepa Bhartiya,Nitu Jha,Shruti Dutta et al.
Deepa Bhartiya et al.
Measurable residual disease (MRD) testing has transformed the management of hematologic cancers by enabling detection of residual malignant cells after therapy. Current approaches rely on qPCR and next-generation sequencing to monitor leuke...
Optimized Metabolic Conditions Reveal the Adipogenic Competence of Wharton's Jelly MSCs: Insight from Literature Review and Experimental Validation [0.03%]
优化的代谢条件揭示了沃顿胶间充质干细胞的向脂分化潜能：文献回顾与实验验证的见解
Cécile Pinault,Audrey Cras,Michel-Gabriel Cazenave et al.
Cécile Pinault et al.
Mesenchymal stromal/stem cells (MSCs) derived from distinct tissue niches exhibit marked functional heterogeneity, yet the determinants governing their adipogenic competence remain incompletely understood. Wharton's jelly MSCs (WJ-MSCs) are...