Nanoceria as Next-Generation Immunotherapeutics: Applications in Chronic Inflammation, Cancer, and Tissue Repair [0.03%]
纳米氧化铈作为下一代免疫疗法:在慢性炎症、癌症和组织修复中的应用
Kay Hadrick,Panangattukara Prabhakaran Praveen Kumar,Taeho Kim
Kay Hadrick
The immune system is crucial in protecting against disease, but it can also contribute to chronic illnesses when it malfunctions, with different conditions involving either inflammation or immune suppression. Current treatments often fall s...
Panangattukara Prabhakaran Praveen Kumar,Maggie Lee,Taeho Kim
Panangattukara Prabhakaran Praveen Kumar
Nanotechnology advancements have resulted in many sensors and devices for biomedical applications. Among the various nanomaterials, gold nanoparticles (AuNPs), due to their size, shape, biocompatibility, and unique plasmonic property, are a...
Daisy L Wilson,Jyoti Ahlawat,Mahesh Narayan
Daisy L Wilson
The use of carbon nanomaterials including fullerenes, carbon nanotubes, carbon nano-onions, carbon dots and carbon quantum dots for environmental applications has increased substantially. These nanoparticles are now used in the development ...
Enhancing Antibody Exposure in the Central Nervous System: Mechanisms of Uptake, Clearance, and Strategies for Improved Brain Delivery [0.03%]
改善抗体在中枢神经系统的暴露:摄取、清除机制及提高脑部递送策略
Kelly Schwinghamer,Teruna J Siahaan
Kelly Schwinghamer
Antibodies (mAbs) are attractive molecules for their application as a diagnostic and therapeutic agent for diseases of the central nervous system (CNS). mAbs can be generated to have high affinity and specificity to target molecules in the ...
Mohammad Mohtasim Hamid Pial,Asahi Tomitaka,Nezih Pala et al.
Mohammad Mohtasim Hamid Pial et al.
Breast cancer is one of the leading causes of death in the female population worldwide. Standard treatments such as chemotherapy show noticeable results. However, along with killing cancer cells, it causes systemic toxicity and apoptosis of...
Antibody Delivery into the Brain by Radiosensitizer Nanoparticles for Targeted Glioblastoma Therapy [0.03%]
放射增敏纳米颗粒递送抗体用于靶向胶质母细胞瘤治疗
Omer Gal,Oshra Betzer,Liat Rousso-Noori et al.
Omer Gal et al.
Background: Glioblastoma is the most lethal primary brain malignancy in adults. Standard of care treatment, consisting of temozolomide (TMZ) and adjuvant radiotherapy (RT), mostly does not prevent local recurrence. The in...
The Nanotheranostic Researcher's Guide for Use of Animal Models of Traumatic Brain Injury [0.03%]
纳米治疗研究中使用创伤性脑损伤动物模型的指南
Brandon Z McDonald,Connor C Gee,Forrest M Kievit
Brandon Z McDonald
Traumatic brain injury (TBI) is currently the leading cause of injury-related morbidity and mortality worldwide, with an estimated global cost of USD 400 billion annually. Both clinical and preclinical behavioral outcomes associated with TB...