Inflammatory Bowel Disease from the Perspective of Newer Innate Immune System Biomarkers [0.03%]
从新的固有免疫系统生物标志物看炎症性肠病
Martin Tobi,Fadi Antaki,MaryAnn Rambus et al.
Martin Tobi et al.
Background: The perspective of inflammatory bowel disease (IBD) has changed radically since the first decade of the 21st century, and the formerly monolithic components of IBD, ulcerative colitis (UC), and Crohn's disease...
Prospective Visual Inspection of the Ventrum of Tongue (VIVOT) Vasculature Predicts the Presence of Esophageal Varices [0.03%]
舌腹血管的前瞻性视觉检查(VIVOT)可预测食管静脉曲张的存在
Martin Tobi,Monina Pascua,Rebecca Rodriguez et al.
Martin Tobi et al.
Venous collateral shunting of blood from the splanchnic to systemic venous systems due to portal hypertension increases the pressure in the ventral lingual venous bed. We hypothesized that the appearance of sublingual varices evaluated by p...
Impact of Probiotics and Prebiotics on Gut Microbiome and Hormonal Regulation [0.03%]
益生菌和益生元对肠道微生物组及激素调节的影响
Jelina Basnet,Manar A Eissa,Licy L Yanes Cardozo et al.
Jelina Basnet et al.
The gut microbiome plays a crucial role in human health by influencing various physiological functions through complex interactions with the endocrine system. These interactions involve the production of metabolites, signaling molecules, an...
The Innate Immune System Surveillance Biomarker p87 in African Americans and Caucasians with Small High-Grade Dysplastic Adenoma [SHiGDA] and Right-Sided JAK3 Colon Mutations May Explain the Presence of Multiple Cancers Revealing an Important Minority of Patients with JAK3 Mutations and Colorectal Neoplasia [0.03%]
非洲裔美国人和高加索人中存在小型高级别肠上皮内瘤变（SHiGDA）和右半结肠JAK3突变的先天免疫系统监测生物标志物p87可能解释了多种癌症的存在，揭示了JAK3突变和大肠肿瘤患者中的一个重要亚组
Martin Tobi,Xiaoqing Zhao,Rebecca Rodriquez et al.
Martin Tobi et al.
Colorectal cancer (CRC) outcomes in terms of incidence and mortality are significantly worse in African Americans than other Americans. While differences in primary preventions for neoplasia (diet, obesity remediation, aspirin prophylaxis) ...
Enteric Nervous System Alterations in Inflammatory Bowel Disease: Perspectives and Implications [0.03%]
炎症性肠病中的肠神经系统改变：观点与影响
Shubhankar Suman
Shubhankar Suman
The enteric nervous system (ENS), consisting of neurons and glial cells, is situated along the gastrointestinal (GI) tract's wall and plays a crucial role in coordinating digestive processes. Recent research suggests that the optimal functi...
The Multifactorial Etiopathogeneses Interplay of Inflammatory Bowel Disease: An Overview [0.03%]
炎症性肠病的多因素病因互作机制概述
Amosy E M&#x;Koma
Amosy E M&#x;Koma
The gastrointestinal system where inflammatory bowel disease occurs is central to the immune system where the innate and the adaptive/acquired immune systems are balanced in interactions with gut microbes under homeostasis conditions. This ...
Cardiomyocyte-specific circulating cell-free methylated DNA in esophageal cancer patients treated with chemoradiation [0.03%]
食管癌患者接受放化疗后心脏细胞特异性循环游离高甲基化DNA检测
Sarah Martinez Roth,Eveline E Vietsch,Megan E Barefoot et al.
Sarah Martinez Roth et al.
Thoracic high dose radiation therapy (RT) for cancer has been associated with early and late cardiac toxicity. To assess altered rates of cardiomyocyte cell death due to RT we monitored changes in cardiomyocyte-specific, cell-free methylate...
Immunomodulatory Effects of TGF-β Family Signaling within Intestinal Epithelial Cells and Carcinomas [0.03%]
TGF-β家族信号在肠道上皮细胞和癌细胞中的免疫调节作用
Paula Marincola Smith,Anna L Means,R Daniel Beauchamp
Paula Marincola Smith
TGF-β superfamily signaling is responsible for many critical cellular functions including control of cell growth, cell proliferation, cell differentiation, and apoptosis. TGF-β appears to be critical in gastrulation, embryonic development...
Characteristics and Clinical Outcomes of Individuals at High Risk for Pancreatic Cancer: A Descriptive Analysis from a Comprehensive Cancer Center [0.03%]
高风险胰腺癌个体的临床特征和结果：一家全面癌症中心的描述性分析
Griffin P J McNamara,Karla N Ali,Shraddha Vyas et al.
Griffin P J McNamara et al.
Pancreatic cancer (PC), a leading cause of cancer-related deaths in the United States, is typically diagnosed at an advanced stage. To improve survival, there is an unmet need to detect pre-malignant lesions and early invasive disease. Prim...