Considerations for the development of a field-based medical device for the administration of adjunctive therapies for snakebite envenoming [0.03%]
基于现场的蛇咬伤联合治疗设备开发考量因素
R Marshall Werner,Allison N Soffa
R Marshall Werner
The timely administration of antivenom is the most effective method currently available to reduce the burden of snakebite envenoming (SBE), a neglected tropical disease that most often affects rural agricultural global populations. There is...
Identification and cross-species comparison of in vitro phase I brevetoxin (BTX-2) metabolites in northern Gulf of Mexico fish and human liver microsomes by UHPLC-HRMS(/MS) [0.03%]
UHPLC-HRMS（/MS）识别和跨物种比较北部墨西哥湾鱼类和人肝微粒体中体外Ⅰ相石房蛤毒素（BTX-2）代谢物
Jessica Kay Gwinn,Alison Robertson,Lada Ivanova et al.
Jessica Kay Gwinn et al.
Brevetoxins (BTX) are a group of marine neurotoxins produced by the harmful alga Karenia brevis. Numerous studies have shown that BTX are rapidly accumulated and metabolized in shellfish and mammals. However, there are only limited data on ...
Timber rattlesnake (Crotalus horridus): Biology, conservation, and envenomation in the Upper Mississippi River Valley (1982-2020) [0.03%]
东部响尾蛇（Crotalus horridus）：上密西西比河谷的生物学、保护和中毒事件（1982-2020）
D E Keyler
D E Keyler
The Timber Rattlesnake (Crotalus horridus) is the largest pit viper in the Northern United States and is the prominent venomous snake species indigenous to the bluff land habitats of the Upper Mississippi River Valley (UMRV). Conservation o...
Co-occurrence of marine and freshwater phycotoxins in oysters, and analysis of possible predictors for management [0.03%]
海洋和淡水贝毒在牡蛎中的共存及管理可能性预测分析
Sarah K D Pease,Todd A Egerton,Kimberly S Reece et al.
Sarah K D Pease et al.
Oysters (Crassostrea virginica) were screened for 12 phycotoxins over two years in nearshore waters to collect baseline phycotoxin data and to determine prevalence of phycotoxin co-occurrence in the commercially and ecologically-relevant sp...
Vasodilator activity of Poecilotheria ornata venom involves activation of the NO/cGMP pathway and inhibition of calcium influx to vascular smooth muscle cells [0.03%]
孟加拉虎蜘蛛(Poecilotheria ornata) 毒液的血管舒张活性涉及NO/cGMP途径活化和抑制钙离子内流到血管平滑肌细胞中
Enrique de Jesus-López,Luis Cuéllar-Balleza,Luis Fernando Díaz-Peña et al.
Enrique de Jesus-López et al.
Tarantula venoms may be a natural source of new vasodilator components useful in pharmacological research. Moreover, biological function data of the venoms are important to enhance the knowledge about the biodiversity and evolution of these...
Clinical effects of immunization, bleeding, and albumin-based fluid therapy in horses used as immunoglobulin source to produce a polyspecific antivenom (Echitab-plus-ICP) towards venoms of African snakes [0.03%]
马用作多特异抗蛇毒血清（Echitab-plus-ICP）原料的免疫、采血及白蛋白输液治疗的临床效果：非洲蛇类蛇毒研究
Rose Mary Huertas,Mauricio Arguedas,Juan Manuel Estrada et al.
Rose Mary Huertas et al.
During the production of snake antivenoms, the animals used as immunoglobulin source are subjected to processes that could deteriorate their physical condition. Therefore, these conditions must be carefully designed and validated. In this w...
Neurologic and hematologic sequalae following a timber rattlesnake (Crotalus horridus) envenomation in a dachshund [0.03%]
一条土拨鼠犬被响尾蛇(Crotalus horridus)咬伤后出现神经和血液方面的症状
Cory Woliver,Michael Schaer
Cory Woliver
A 2-year-old female Dachshund had a witnessed timber rattlesnake envenomation. Although rattlesnake envenomations are a common, potentially life-threatening event in companion animals, timber rattlesnake envenomations in the dog are rarely ...
The safety of botulinum neurotoxin type A's intraarticular application in experimental animals [0.03%]
肉毒杆菌A型毒素关节腔内注射的动物实验安全性研究
Ana Dugonjić Okroša,Victor Ricardo Manuel Muñoz-Lora,Ivica Matak et al.
Ana Dugonjić Okroša et al.
In vivo studies of botulinum neurotoxin type A (BoNT-A) enabled characterization of its activity in the nociceptive sensory system separate from its preferred action in motor and autonomic nerve terminals. However, in the recent rodent stud...
Snakebite care through the first two waves of COVID-19 in West Bengal, India: a qualitative study [0.03%]
印度西孟加拉邦新冠肺炎前两波疫情期间的蛇咬伤救护：一项定性研究
Soumyadeep Bhaumik,Deepti Beri,Anthony B Zwi et al.
Soumyadeep Bhaumik et al.
Snakebite is a public health problem in many countries, with India having the highest number of deaths. Not much is known about the effect of the COVID-19 pandemic on snakebite care. We conducted 20 in-depth interviews with those bitten by ...
Special issue editorial: Resource mapping for the management of snakebite envenomation [0.03%]
专刊序言：毒蛇咬伤治疗用抗蛇毒血清资源制图管理
Wuelton M Monteiro,Hui Wen Fan,Abdulrazaq G Habib et al.
Wuelton M Monteiro et al.