Analysis of commercially available snake antivenoms reveals high contents of endotoxins in some products [0.03%]
市售的蛇抗毒血清的分析显示某些产品含有大量的内毒素
Gabriela Solano,Stuart Ainsworth,Adriana Sánchez et al.
Gabriela Solano et al.
As injectable therapeutics, snake antivenoms must meet specifications for endotoxin content. The Limulus amebocyte lysate (LAL) test was used to evaluate the endotoxin content in several commercially available antivenoms released for clinic...
High-content fluorescence bioassay investigates pore formation, ion channel modulation and cell membrane lysis induced by venoms [0.03%]
高内涵荧光生物分析检测毒液诱导的孔形成、离子通道调节和细胞膜裂解
Simon Kramer,Charan Kotapati,Yuanzhao Cao et al.
Simon Kramer et al.
Venoms comprise highly sophisticated bioactive molecules modulating ion channels, receptors, coagulation factors, and the cellular membranes. This array of targets and bioactivities requires advanced high-content bioassays to facilitate the...
Phytotoxicity effect of a highly toxic isolate of Alternaria alternata metabolites from Iran [0.03%]
来自伊朗的一种高毒性Alternaria alternata代谢物的化感作用效果
Atefeh Sedighi,Abbas Mohammadi
Atefeh Sedighi
Alternaria species produce several mycotoxins, such as alternariol (AOH), alternariol monomethyl ether (AME), altenuene (ALT), altertoxin (ATX), tentoxin (TTX) and tenuazonic acid (TeA). This research aimed to isolate and identify mycotoxin...
Intrageneric cross-reactivity of monospecific rabbit antisera against venoms of mamba (Elapidae: Dendroaspis spp.) snakes [0.03%]
单特异性兔抗血清对绿慕蛇( Elapidae : Dendroaspis spp. )毒液的属内交叉反应性
Aarón Gómez,Andrés Sánchez,Gina Durán et al.
Aarón Gómez et al.
Snakebite envenomation is a neglected tropical disease posing a high toll of mortality and morbidity in sub-Saharan Africa. Polyspecific antivenoms of broad effectiveness and specially designed for this region require a detailed understandi...
Geographical and temporal distribution of Megalopygidae in the United States and Puerto Rico [0.03%]
在美国和波多黎各的Megalopygidae的地理分布和时间分布分析
Emilio Peruzzi Sancio,Chris Alice Kratzer,John C Carlson
Emilio Peruzzi Sancio
Background: The venom of Megalopygidae caterpillars causes inflammation and pain. Understanding geographic and temporal variation in exposure will help physicians and the public understand when and where the species in th...
Exploring the potential of Brazilian Amazonian scorpion venoms: A comprehensive review of research from 2001 to 2021 [0.03%]
探索巴西亚马逊蝎子毒液的潜力：对2001年至2021年研究的全面回顾
Joel Ramanan da Cruz,Philippe Bulet,Cléria Mendonça de Moraes
Joel Ramanan da Cruz
The Amazon biome is home to many scorpion species, with around two hundred identified in the region. Of these, forty-eight species have been reported in Brazil so far and six of them are of medical importance: Tityus apiacas, T. metuendus, ...
A plethora of rodents: Rattlesnake predators generate unanticipated patterns of venom resistance in a grassland ecosystem [0.03%]
鼠类大量存在：响尾蛇的捕食者在草原生态系统中产生了意想不到的抗毒模式
Neil R Balchan,Cara F Smith,Stephen P Mackessy
Neil R Balchan
Predation has the potential to impart strong selective pressures on organisms within their environments, resulting in adaptive changes in prey that minimize risk of predation. Pressures from venomous snakes present an exceptional challenge ...
Snake venom cysteine-rich secretory protein from Mojave rattlesnake venom (Css-CRiSP) induces acute inflammatory responses on different experimental models [0.03%]
莫哈韦响尾蛇毒液中的半胱氨酸富集分泌蛋白诱发不同模型的小鼠产生急性炎症反应
Emelyn Salazar,Abcde Cirilo,Armando Reyes et al.
Emelyn Salazar et al.
Snake venoms contain various molecules known for activating innate immunity and causing local effects associated with increased vascular permeability, such as vascular leakage and edema, common symptoms seen in snakebite envenomings. We hav...
Geographic variation in the clinical features of Mohave rattlesnake (Crotalus scutulatus) envenomations reported to the North American Snakebite Registry [0.03%]
北美蛇咬登记中心报告的莫哈维响尾蛇(Crotalus scutulatus)蛇咬患者的临床特征地理分布差异
Spencer Greene,Matthew Gilbert,Brian Wolk et al.
Spencer Greene et al.
The geographic variation of Mohave rattlesnake (Crotalus scutulatus) venom is well established. We reviewed all the Mohave rattlesnake bites reported to the Toxicology Investigators Consortium's North American Snakebite Registry between Jan...
Rhabdomyolysis due to unidentified jellyfish envenomation in west Malaysian waters [0.03%]
西马来西亚海域不明水母所致横纹肌溶解症病例报告
Jia Shyi Loy,Chyi Chyi Khoo,Tilagavahti Arumugam et al.
Jia Shyi Loy et al.
Jellyfish envenomation is a common marine injury. We report a case of a 9-year-old boy who developed muscle weakness and rhabdomyolysis after a jellyfish sting. He was stung on the face, hands, and feet. He sustained immediate pain and numb...
Case Reports
Toxicon: X. 2023 Nov 2:21:100170. DOI:10.1016/j.toxcx.2023.100170 2023