Increased mortality associated with frequent exacerbations in COPD patients with mild-to-moderate lung function impairment, and smokers with normal spirometry [0.03%]
轻至中度肺功能损伤的慢性阻塞性肺疾病患者和肺量计检测正常的吸烟者频繁急性加重与死亡率增加有关
Spyridon Fortis,Emily S Wan,Ken Kunisaki et al.
Spyridon Fortis et al.
Background: The burden of frequent respiratory exacerbations in COPD patients with mild-to-moderate spirometric impairment and smokers with preserved lung function is unknown. ...
Converging pathways in pulmonary fibrosis and Covid-19 - The fibrotic link to disease severity [0.03%]
肺纤维化和Covid-19的汇聚途径——与疾病严重性相关的纤维化联系
Jenny Wigén,Anna Löfdahl,Leif Bjermer et al.
Jenny Wigén et al.
As Covid-19 affects millions of people worldwide, the global health care will encounter an increasing burden of the aftermaths of the disease. Evidence shows that up to a fifth of the patients develop fibrotic tissue in the lung. The SARS o...
T cell Co-Stimulatory molecules ICOS and CD28 stratify idiopathic pulmonary fibrosis survival [0.03%]
共刺激分子ICOS和CD28可对特发性肺纤维化患者的预后进行分层
Catherine A Bonham,Cara L Hrusch,Kelly M Blaine et al.
Catherine A Bonham et al.
Idiopathic pulmonary fibrosis (IPF) is a devastating disease that kills as many Americans as breast cancer each year. This study investigated whether lung function decline and survival associates with adaptive immunity in patients with IPF,...
Tocilizumab in sarcoidosis patients failing steroid sparing therapies and anti-TNF agents [0.03%]
糖皮质激素诱导缓解治疗及抗肿瘤坏死因子药物疗效不佳的韦格纳肉芽肿患者使用托珠单抗治疗
Michelle Sharp,Seamas C Donnelly,David R Moller
Michelle Sharp