Does vitamin D status impact mortality from SARS-CoV-2 infection? [0.03%]
维生素D状况会影响SARS-CoV-2感染的死亡率吗？
Paul E Marik,Pierre Kory,Joseph Varon
Paul E Marik
Can early and high intravenous dose of vitamin C prevent and treat coronavirus disease 2019 (COVID-19)? [0.03%]
早期大剂量静脉注射维生素C能预防和治疗新型冠状病毒肺炎吗？
Richard Z Cheng
Richard Z Cheng
Hiroshi Maruta,Hong He
Hiroshi Maruta
PAK1 (RAC/CDC42-activated kinase 1) is the major "pathogenic" kinase whose abnormal activation causes a wide variety of diseases/disorders including cancers, inflammation, malaria and pandemic viral infection including influenza, HIV and CO...
Su M Metcalfe
Su M Metcalfe
Human coronavirus, hCoV-19, is highly pathogenic with severe pneumonia associated with rapid virus replication. Arising in Wuhan China December 2019, the current COVID-19 epidemic has rapidly grown with person-to-person infection expanding ...
Target Virus or Target Ourselves for COVID-19 Drugs Discovery?-Lessons learned from anti-influenza virus therapies [0.03%]
以靶点病毒还是靶点我们自身为新冠肺炎药物发现的目标？抗流感疗法的启示
Jiayu Liao,George Way,Vipul Madahar
Jiayu Liao
The COVID-19 pandemic, after it was reported in December 2019, is a highly contagious and now spreading to over 190 countries, causing a severe public health burden. Currently, there is no vaccine or specific drug to treat COVID-19, which i...
Meeting the potential emergency global drug supply challenge of hydroxychloroquine for COVID-19 [0.03%]
应对羟氯喹潜在全球紧急供药挑战以应对新冠肺炎疫情
Tony Y Zhang,Boyu Zhong
Tony Y Zhang
This paper provides an overview of the current global market and manufacturing landscape for hydroxychloroquine (HCQ). The capacity and capabilities of global producers to meet the potential demand for treating patients inflicted with COVID...
Kim D Janda,Michael J Iadarola
Kim D Janda
The role of afferent pulmonary innervation in ARDS associated with COVID-19 and potential use of resiniferatoxin to improve prognosis: A review [0.03%]
COVID-19相关性ARDS患者的肺传入神经作用及其应用树脂素改善预后的潜力：一综述
Alexis Nahama,Roshni Ramachandran,Alvaro Francisco Cisternas et al.
Alexis Nahama et al.
Acute respiratory distress syndrome (ARDS) is one of the major causes of mortality associated with COVID-19 disease. Many patients will require intensive care with ventilatory support. Despite progress and best efforts, the mortality rates ...
Novel decoy cellular vaccine strategy utilizing transgenic antigen-expressing cells as immune presenter and adjuvant in vaccine prototype against SARS-CoV-2 virus [0.03%]
一种新型的针对SARS-CoV-2病毒的疫苗策略，利用转基因抗原表达细胞作为免疫呈递器和佐剂的诱骗细胞疫苗原型研究
Henry Ji,Ying Yan,Beibei Ding et al.
Henry Ji et al.
A novel approach modifying cells to express viral markers to elicit protective immunity responses (decoy cellular vaccination) in the prevention of COVID-19 disease is currently being explored. Our approach entails utilizing SARS-CoV-2 Spik...