Hanxiao Yu,He Yang,Enxue Shi et al.
Hanxiao Yu et al.
Phosphorus-containing drugs belong to an important class of therapeutic agents and are widely applied in daily clinical practices. Structurally, the phosphorus-containing drugs can be classified into phosphotriesters, phosphonates, phosphin...
Viral sepsis is a complication in patients with Novel Corona Virus Disease (COVID-19) [0.03%]
病毒感染性败血症是新型冠状病毒疾病(COVID-19)患者的并发症之一
Di Liu,Qiang Wang,Huacai Zhang et al.
Di Liu et al.
Background: Until June 23th 2020, 9,195,635 laboratory-confirmed cases of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection have been reported worldwide, including 473,127 deaths. Bacterial infection ...
Cyclophilin A and CD147: novel therapeutic targets for the treatment of COVID-19 [0.03%]
环孢菌素A和CD147:治疗COVID-19的新疗法目标
Chenglong Liu,Albrecht von Brunn,Di Zhu
Chenglong Liu
The outbreak of pneumonia caused by a new coronavirus (SARS-CoV-2) occurred in December 2019, and spread rapidly throughout the world. There have been other severe coronavirus outbreaks worldwide, namely, severe acute respiratory syndrome (...
Vitamin D Levels and COVID-19 Susceptibility: Is there any Correlation? [0.03%]
维生素D水平与COVID-19易感性之间存在任何关联吗?
Karan Razdan,Kuldeep Singh,Dilpreet Singh
Karan Razdan
Coronavirus disease (COVID-19) is a major pandemic and now a leading cause of death worldwide. Currently, no drugs/vaccine is available for the treatment of this disease. Future preventions and social distancing are the only ways to prevent...
BCG vaccination strategy implemented to reduce the impact of COVID-19: Hype or Hope? [0.03%]
实施BCG疫苗策略以减少COVID-19的影响:炒作还是希望?
Keshav Rajarshi,Aroni Chatterjee,Shashikant Ray
Keshav Rajarshi
The Bacillus Calmette-Guerin vaccine (BCG vaccine) designed to prevent tuberculosis in children has been shown to induce a adaptive immune response in the body to fight against bacteria as well as other parasites and viruses. This knowledge...
Mohammad A Uddin,Khadeja-Tul Kubra,Jafrin Jobayer Sonju et al.
Mohammad A Uddin et al.
Inhibition of Hsp90 is associated with anti-inflammatory effects. We employed human lung microvascular endothelial cells to investigate the effects of the Hsp90 inhibitors 17-AAG, AUY-922 and 17-DMAG in the unfolded protein response (UPR) a...
Can We Reduce Mortality of COVID-19 if We do Better in Glucose Control? [0.03%]
更好的血糖控制能否降低COVID-19的死亡率?
Mingyan Deng,Ling Jiang,Yan Ren et al.
Mingyan Deng et al.
The SARS-CoV-2 has infected more than 3 million people and caused more than 240,000 death globally. Among the COVID-19 patients, the prevalence of people with other chronic diseases, such as diabetes, high blood pressure, and coronary heart...
Inhibition of metalloproteinases in therapy for severe lung injury due to COVID-19 [0.03%]
金属蛋白酶抑制剂在治疗由新型冠状病毒引起的严重肺损伤中的作用
B Solun,Y Shoenfeld
B Solun
Since its first appearance in December 2019 in the Chinese province of Wuhan, COVID-19 has spread rapidly throughout the world and poses a serious threat to public health. Acute respiratory failure due to widespread lung inflammation progre...
Melatonin Inhibits COVID-19-induced Cytokine Storm by Reversing Aerobic Glycolysis in Immune Cells: A Mechanistic Analysis [0.03%]
褪黑素通过逆转免疫细胞有氧糖酵解抑制COVID-19诱导的细胞因子风暴:机制分析
Russel J Reiter,Ramaswamy Sharma,Qiang Ma et al.
Russel J Reiter et al.
Perspectives for the use of therapeutic Botulinum toxin as a multifaceted candidate drug to attenuate COVID-19 [0.03%]
肉毒杆菌素作为治疗新冠肺炎的多面性候选药物的应用前景展望
Mahesh Kandasamy
Mahesh Kandasamy
The recent outbreak of coronavirus disease (COVID-19) resulting from a distinctive severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) continues to evolve in many countries and pose life-threatening clinical issues to global public...