Genetic and Clinical Progression of MYSM1 Related Bone Marrow Failure into Myeloid Malignancies: Case Series and Review of Literature [0.03%]
MYSM1相关骨髓衰竭向髓系恶性肿瘤进展的遗传和临床特点:病例系列及文献回顾
Alfadil Haroon,Syed Osman Ahmed,Chokri Ben Lamine et al.
Alfadil Haroon et al.
MYSM1, located on chromosome 1p32.1, encodes histone H2A deubiquitinase, a transcription regulator involved in DNA damage response. Biallelic MYSM1 variants are linked to rare bone marrow failure syndromes, presenting with cytopenia, B-cell...
Impact of Anemia Management on Bleeding Outcomes in Anticoagulated Patients: A Retrospective Cohort Analysis [0.03%]
抗凝患者的贫血管理对出血结局的影响:回顾性队列分析
Shea-Lee Godin,Christopher Hanna,Edgar Naut et al.
Shea-Lee Godin et al.
Anticoagulation therapy is essential to manage thromboembolic conditions such as atrial fibrillation and venous thromboembolism. While effective, it carries significant bleeding risks, with annual rates ranging from 10-17% for all events an...
Relapsed/refractory multiple myeloma: standard of care management of patients in the Gulf region [0.03%]
复发/难治性多发性骨髓瘤:海湾国家患者的标准治疗护理标准
Ahmad Alhuraiji,Khalil Al Farsi,Kayane Mheidly et al.
Ahmad Alhuraiji et al.
Clinical management of patients with relapsed/refractory multiple myeloma (RRMM) can be challenging, whereby each relapse is associated with progressively poorer outcomes. In addition, changes in disease biology and patient characteristics ...
Consensus Guidelines and Recommendations for The CD38 Monoclonal Antibody-based Quadruplet Therapy and Management in Clinical Practice for Newly Diagnosed Multiple Myeloma: From the Pan-Pacific Multiple Myeloma Working Group [0.03%]
浆细胞瘤工作组关于新诊断多发性骨髓瘤达雷妥尤单抗基四药方案治疗的临床实践专家共识及推荐意见
Wenming Chen,Zhen Cai,James Cs Chim et al.
Wenming Chen et al.
The therapeutic outcomes of clinical trials for incorporating anti-CD38 monoclonal antibodies (including isatuximab and daratumumab) into the bortezomib/lenalidomide/dexamethasone (VRd) triplet therapy backbone as the first-line treatment f...
Robin Noel,Aude Charbonnier,Bérénice Schell et al.
Robin Noel et al.
Prolonged Cytopenia with CAR-T Cell Therapy and Management Recommendations [0.03%]
CAR-T细胞治疗后长期的细胞减少及其处理建议
Debolanle Dahunsi,Cynthia Eleanya,Akintomiwa Akintunde et al.
Debolanle Dahunsi et al.
Chimeric antigen receptor T-cell (CAR T-cell) therapy has revolutionized the treatment of lymphoid malignancies. Prolonged cytopenias, though poorly understood, have emerged as important considerations in the treatment process. In this revi...
Efficacy and safety of primary letermovir prophylaxis for cytomegalovirus infection in paediatric patients undergoing allogeneic transplantation: a single-centre, retrospective, real-world analysis [0.03%]
勒特莫韦原发预防儿童患者异体移植后巨细胞病毒感染的有效性和安全性:单中心、回顾性、现实世界分析
Xin Wang,Chaoqian Jiang,Lipeng Liu et al.
Xin Wang et al.
Background: Cytomegalovirus (CMV) infection is a common and life-threatening complication following allogeneic haematopoietic stem cell transplantation (allo-HSCT). Letermovir (LET) has been the standard prophylaxis for a...
Therapeutics of acute myeloid leukemia with central nervous system involvement [0.03%]
中枢神经系统受累的急性髓系白血病的治疗研究
Edwin U Suárez,Tamara Castaño-Bonilla,Rocio Salgado et al.
Edwin U Suárez et al.
FLT3-mutated acute myeloid leukemia (AML) with central nervous system (CNS) involvement poses therapeutic challenges. We describe two cases and performed a systematic review evaluating the efficacy of therapeutic strategies in CNS involveme...
Frontline management of multiple myeloma patients: optimizing treatment for patients in the Gulf region [0.03%]
华氏巨球蛋白血症患者的前线管理:优化海湾地区患者的治疗方案
Mahmoud Marashi,Khalil Al Farsi,Hussni Al Hateeti et al.
Mahmoud Marashi et al.
Treatment options for newly diagnosed multiple myeloma (NDMM) have expanded dramatically over the last two decades, resulting in remarkable improvements in response rates and median survival times. In eligible patients, autologous stem cell...
Mohamad Mohty,Junia V Melo
Mohamad Mohty
High-quality peer review is a cornerstone of credible and impactful scientific and medical publishing. This manuscript provides a comprehensive overview of the best practices, responsibilities, and evaluation criteria for peer reviewers in ...