Marta Palomo,Maribel Diaz-Ricart,Enric Carreras
Marta Palomo
The goal of this review is to look at the role of endothelial damage and dysfunction in the initiation and development of early complications that appear after hematopoietic cell transplantation (HCT). These early complications share overla...
Iskra Pusic,Steven Z Pavletic
Iskra Pusic
The lack of standardized criteria for measuring therapeutic response has been a major obstacle to the development of therapeutic trials in chronic graft-versus-host disease (cGvHD). Nevertheless, recent advances have been made in understand...
Fecal Microbiota Transplantation for Treatment of Acute Graft- versus-Host Disease [0.03%]
粪菌移植治疗急性格移植物抗宿主病
Roni Shouval,Mika Geva,Arnon Nagler et al.
Roni Shouval et al.
The growing understanding of the bidirectional relationship between the gastrointestinal (GI) microbiome and the immune system has opened up new avenues for treatment of graft-versus-host disease (GVHD). Fecal microbiota transplantation (FM...
Current Status and Perspectives of Irradiation-Based Conditioning Regimens for Patients with Acute Leukemia Undergoing Hematopoietic Stem Cell Transplantation [0.03%]
急性白血病患者进行造血干细胞移植时放射预处理方案的应用现状及前景
Rashmika R Potdar,Sorab Gupta,Sebastian Giebel et al.
Rashmika R Potdar et al.
Acute myeloid leukemia and acute lymphoblastic leukemia are the most common indications for allogeneic hematopoietic stem cell transplantation. Total body irradiation (TBI) is an important part of conditioning regimens. TBI-based regimens o...
Jonathan Canaani
Jonathan Canaani
The therapeutic paradigm for treatment of acute myeloid leukemia (AML) is rapidly changing with the advent of a new generation of drugs targeting diverse aspects of leukemogenesis. Whereas standard treatment for AML until recently consisted...
Therapeutic Approaches for Blastic Plasmacytoid Dendritic Cell Neoplasm: Allogeneic Hematopoietic Cell Transplantation and Novel Therapies [0.03%]
浆细胞样树突状细胞肿瘤的治疗手段：异基因造血细胞移植和新型疗法
Mohamed A Kharfan-Dabaja,Naveen Pemmaraju,Mohamad Mohty
Mohamed A Kharfan-Dabaja
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a clinically aggressive hematologic malignancy derived from precursors of plasmacytoid dendritic cells. There is no established standard therapy for BPDCN and the efficacy of conventio...
Clinical Hematology International: Why a New Journal in Hematology? [0.03%]
临床血液学国际：为什么要在血液病领域出版一种新杂志？
Mohamad Mohty,Arnon Nagler,Bipin Savani
Mohamad Mohty
Anas Zahid,Elizabeth L Siegler,Saad S Kenderian
Anas Zahid
T cells genetically engineered with chimeric antigen receptors (CART) have become a potent class of cancer immunotherapeutics. Numerous clinical trials of CART cells have revealed remarkable remission rates in patients with relapsed or refr...
B cell deficiency in patients with relapsed and refractory acute myeloid leukemia [0.03%]
复发和难治性急性髓系白血病患者的B细胞缺乏症
Meghali Goswami,Katherine E Lindblad,Rahul Ramraj et al.
Meghali Goswami et al.
Jacob Shreve,Aziz Nazha
Jacob Shreve
Myelodysplastic syndromes (MDSs) are potentially devastating monoclonal deviations of hematopoiesis that lead to bone marrow dysplasia and variable cytopenias. Predicting severity of disease progression and likelihood to undergo acute myelo...