Nanosphere's Verigene® Blood Culture Assay to Detect Multidrug-Resistant Gram-Negative Bacterial Outbreak: A Prospective Study on 79 Hematological Patients in a Country with High Prevalence of Antimicrobial Resistance [0.03%]
纳米球Verigene®血液培养检测耐多药革兰氏阴性细菌暴发：在高抗菌素耐药国家的79名血液病患者的前瞻性研究
Raffaella Greco,Maria Chiara Barbanti,Nicasio Mancini et al.
Raffaella Greco et al.
Infections are a major cause of morbidity and mortality in hematological patients. We prospectively tested a new molecular assay (Verigene®) in 79 consecutive hematological patients, with sepsis by gram-negative bacteria. A total of 82 gra...
Engraftment Syndrome: A Retrospective Analysis of the Experience at a Tertiary Care Institute [0.03%]
移植物抗宿主病综合症：在三级医疗机构中的回顾性分析
Raja Pramanik,Harish Kancharla,Sameer Bakhshi et al.
Raja Pramanik et al.
Engraftment syndrome (ES) is a clinical syndrome that occurs in the early neutrophil recovery phase following hematopoietic stem cell transplant (HSCT). Although also described for allogenic HSCT, it is basically diagnosed in the context of...
Safety and Efficacy of Haploidentical Peripheral Blood Stem Cell Transplantation for Myeloid Malignancies Using Post-transplantation Cyclophosphamide and Anti-thymocyte Globulin as Graft- versus-Host Disease Prophylaxis [0.03%]
使用移植后环磷酰胺和抗胸腺球蛋白作为移植物抗宿主病预防措施，用于髓系恶性肿瘤的半同基因外周血干细胞移植的安全性和有效性研究
Maria Queralt Salas,Arjun Datt Law,Wilson Lam et al.
Maria Queralt Salas et al.
Haploidentical stem cell transplantation (haploSCT) has greatly improved access to curative treatment for myeloid malignancies in patients without suitable matched sibling/unrelated donors. We investigated the safety and efficacy of haploSC...
Low-Dose Acyclovir Prophylaxis for Varicella zoster Reactivation in Autologous Hematopoietic Cell Transplantation Recipients [0.03%]
自体造血细胞移植受者水痘带状疱疹病毒再活化的低剂量阿昔洛韦预防治疗
Naomi Fei,Nilay Shah,Aaron Cumpston et al.
Naomi Fei et al.
Varicella zoster virus (VZV) reactivation after autologous hematopoietic cell transplantation (auto-HCT) may be observed in a quarter of patients. Currently, prophylactic use of acyclovir 800 mg twice daily or valacyclovir 500 mg twice dail...
Salvage Therapy after Allogeneic Hematopoietic Cell Transplantation: Targeted and Low-Intensity Treatment Options in Myelodysplastic Syndrome and Acute Myeloid Leukemia [0.03%]
异基因血液干细胞移植后的补救治疗：骨髓增生异常综合症和急性髓性白血病的针对性及低强度治疗选择
Katie Culos,Michael Byrne
Katie Culos
Patients with high-risk myeloid neoplasms, including myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), are offered allogeneic hematopoietic cell transplantation (alloHCT) to improve the likelihood of long-term disease control...
Treatment of Adult Patients with Relapsed/Refractory B-Cell Philadelphia-Negative Acute Lymphoblastic Leukemia [0.03%]
成人复发或难治性B细胞费城阴性急性淋巴细胞白血病的治疗
Enrico Maffini,Francesco Saraceni,Francesco Lanza
Enrico Maffini
The majority of adult patients affected by B-cell acute lymphoblastic leukemia (B-ALL) will relapse after an initial response, while approximately 20% will display primary resistant disease. Patients suffering from relapsed/refractory B-ALL...
Relapse and Resistance to CAR-T Cells and Blinatumomab in Hematologic Malignancies [0.03%]
血液恶性肿瘤中CAR-T细胞和Blinatumomab的复发与耐药性问题
Elad Jacoby
Elad Jacoby
Application of immunotherapeutic modalities changed paradigms in the treatment of hematologic malignancies, with regards to drug manufacturing, treatment protocols, short- and long-term toxicities. FDA-approved therapies, including blinatum...
Rishabh Gupta,Ujjawal Savani,Katie Gatwood et al.
Rishabh Gupta et al.
Allogeneic Stem Cell Transplantation for FLT3-Mutated Acute Myeloid Leukemia: In vivo T-Cell Depletion and Posttransplant Sorafenib Maintenance Improve Survival. A Retrospective Acute Leukemia Working Party-European Society for Blood and Marrow Transplant Study [0.03%]
异基因造血干细胞移植治疗FLT3突变的急性髓系白血病：体内T细胞去竭和移植后索拉非尼维持可以提高生存率。一项回顾性欧洲血液和骨髓移植-急性白血病工作组研究
Ali Bazarbachi,Myriam Labopin,Giorgia Battipaglia et al.
Ali Bazarbachi et al.
Acute myeloid leukemia (AML) with FLT3-mutation carries a poor prognosis, and allogeneic stem cell transplantation (allo-SCT) is recommended at first complete remission (CR1). We assessed 462 adults (median age 50 years) with FLT3-mutated A...
Elena E Solomou
Elena E Solomou
"Bone marrow failure" encompass all the conditions and syndromes in which there are qualitative or quantitative disorders of one or more lineages (erythroid, myelomonocytic, and/or megakaryocytic). A few years ago, the pathophysiology of th...