Everolimus initiated in the neonatal period for refractory seizures associated with tuberous sclerosis complex: long-term clinical outcome [0.03%]
新生期起始依维莫司治疗结节性硬化症相关难治性癫痫的长期临床疗效
Yoong-A Suh,Seong Wan Kim,Seohui Choi et al.
Yoong-A Suh et al.
Objective: Everolimus is an established therapy for tumor manifestations and refractory focal seizures in tuberous sclerosis complex (TSC) in patients aged ≥2 years. Evidence regarding its use during the neonatal period,...
Lived experiences that influence the quality of life among patients with epilepsy at Mulago National Referral Hospital [0.03%]
穆拉戈国家转诊医院癫痫患者的生存体验对其生活质量的影响
Humphrey Atwijukiire,Juliana Namutundu,David Lubogo et al.
Humphrey Atwijukiire et al.
Background: In Uganda, the quality of life (QoL) of patients with epilepsy (PWE) remains poor due to clinical, psychological, and social challenges. While several quantitative studies have documented correlates of poor Qo...
Chorea-athetosis-like hyperkinetic seizures in temporal lobe epilepsy: insights from stereo-EEG in three patients [0.03%]
立体脑电图揭示的三项颞叶癫痫患者的舞蹈手足徐动症样阵挛性发作
Jun Zhuang,Lingxia Fei,Hua Li et al.
Jun Zhuang et al.
Purpose: To characterize the clinical and electrographic features of temporal lobe epilepsy (TLE) presenting with chorea-athetosis-like hyperkinetic seizures and to delineate the underlying seizure network using stereo-el...
Seizure freedom after vagus nerve stimulation in a patient with SCN3A-related network epilepsy and incomplete penetrance: A case report [0.03%]
SCN3A相关性网络癫痫不完全外显患者迷走神经刺激术后的无发作状态：一例报告
Victoria Esmeralda Juárez-Rivera,Juan Carlos Vera-López,Diana Trinidad-Hernández et al.
Victoria Esmeralda Juárez-Rivera et al.
Genetic-based epilepsies often present as distributed neural network disorders, challenging traditional focal versus generalized classifications. We report a 20-year-old male with drug-resistant epilepsy associated with a previously unrepor...
The electroclinical phenotype of epilepsy following autoimmune encephalitis [0.03%]
自身免疫性脑炎后癫痫的电临床表型
Stephan Neidhart,Tena Dubcek,Debora Ledergerber et al.
Stephan Neidhart et al.
Objective: To describe the temporal and spatial dynamics of electroencephalographic (EEG) recordings in epilepsy following autoimmune encephalitis (AE) compared to temporal lobe epilepsy (TLE) without signs of inflammator...
Comparative trends in idiopathic epilepsy burden in China and worldwide based on Global Burden of Disease Study 2021 [0.03%]
基于全球疾病负担研究2021的中国和全球特发性癫痫疾病负担趋势比较分析
Xueshi Tian,Yu Geng,Xiang Chen et al.
Xueshi Tian et al.
Background: Idiopathic epilepsy, defined by the absence of identifiable structural or metabolic etiologies, remains a significant contributor to the global neurological disease burden. However, long-term comparisons betwe...
Caregiver burden and associated factors among primary caregivers of children with epilepsy in southwestern Uganda [0.03%]
乌干达西南部癫痫患儿主要照料者的负担及影响因素分析
Godfrey Bapambwire Amooti,Maniple Evard Bikaitwoha,Joseph Namanya et al.
Godfrey Bapambwire Amooti et al.
Background: Globally, caregiver burden in childhood epilepsy is recognized as a major public health concern. However, this phenomenon remains under-studied in Uganda. ...
Expanding the phenotypic Spectrum of ZNF711: Autism and epilepsy in two siblings [0.03%]
ZNF711基因表型谱系的扩大：两个兄弟姐妹中的自闭症和癫痫
Gloria Urciuoli,Nicola Simeone,Marica Rubino et al.
Gloria Urciuoli et al.
Zinc Finger Protein 711 (ZNF711) is a Krüppel-type zinc finger transcription factor highly expressed in the brain and whose mutations have been associated with neurodevelopmental disorders such as intellectual disability, autism spectrum d...
Lived experiences of young people with epilepsy in a resource-constraint setting: Contemporary findings from Cape Coast, Ghana [0.03%]
加纳卡佩海岸资源匮乏地区青少年癫痫患者的生存经历：当代研究发现
Akwasi Appiah,Kwasi Agyen-Mensah,Akua Afriyie Karikari et al.
Akwasi Appiah et al.
Epilepsy is a chronic neurological condition that affects millions of young people globally, often leading to physical, cognitive, psychological, and social challenges. In resource-constraint settings, access to healthcare and medications, ...
Fenfluramine for seizures in Dravet syndrome and Lennox-Gastaut syndrome: Mechanisms, clinical evidence, safety, and practical integration [0.03%]
氟西泮治疗德拉韦综合征和Lennox-Gastaut综合征的癫痫发作：机制、临床证据、安全性及实际应用整合
József Janszky,József Janszky Jr,Réka Horváth
József Janszky
Developmental and epileptic encephalopathies such as Dravet syndrome and Lennox-Gastaut syndrome remain highly drug resistant and are associated with substantial neurodevelopmental, behavioral, and caregiver burdens. Fenfluramine, repurpose...