Nanotherapeutics Mediated Intranasal Delivery for Therapeutic Effect on Parkinson's Disease: Balancing Advancements and Challenges [0.03%]
介导纳米药物鼻内递送治疗帕金森病：在进步和挑战之间的平衡
Pankaj Popli,Barika Rana,Sonia Dhiman et al.
Pankaj Popli et al.
Managing Parkinson's Disease (PD) presents formidable challenges due to the impermeability of the Blood-Brain Barrier (BBB), which severely restricts effective drug delivery. Traditional treatment modalities often prove inadequate, promptin...
A Novel, Stability-indicating Method for Analyzing Degradation Impurities in Hydrochlorothiazide and Irbesartan Tablets Using RP-HPLC [0.03%]
一种用于RP-HPLC测定氢氯噻嗪和厄贝沙坦片中降解杂质的稳定性指示方法研究
Tusharkumar Shah,Smriti Sharma,Jayesh Dhalani
Tusharkumar Shah
Introduction: Well-known antihypertensive medications, hydrochlorothiazide and irbesartan, are sometimes taken as a low-dose combination in a single pill. ...
Searching Heterocyclic Scaffolds Used to Treat Alzheimer's Disease: A Review [0.03%]
用于治疗阿尔茨海默病的杂环骨架的研究进展综述
Mayura A Kale,Mohammed Faisal
Mayura A Kale
It is a known fact that Alzheimer's disease causes degeneration of the central nervous system, which progresses and causes memory loss as well as loss of cognition. For many years, extensive research has been undertaken to find out newer po...
Reviewing the Therapeutic Potential of Plant-based Natural Products against Multidrug-resistant Bacteria (MDR) [0.03%]
植物基天然产物对抗多重耐药细菌(MDR)的治疗潜力综述
Ragini Pandey,Puneet Gupta
Ragini Pandey
The global health of individuals is severely threatened by drug-resistant microorganisms. Existing antibiotics available in the market, such as penicillin, cephalosporins, new β- lactams, aminoglycosides, macrolides, lincomycin, and quinol...
Effects of Cannabis Exposure on Adolescent Health and Development: A Narrative Review [0.03%]
大麻暴露对青少年健康和发育的影响：叙述性综述
Ruixuan Li,Feng Tao
Ruixuan Li
Adolescence is an immature but adventurous time period of exploration. Due to rapid developments of the brain with unbalanced release of neurotransmitters, adolescents are prone to impulsivity that may carry out potentially dangerous behavi...
Radiosensitizing Effects of Metformin on Ionizing Irradiation: An Overview of Animal and Clinical Studies [0.03%]
二甲双胍联合放射治疗的增敏效果：动物和临床研究综述
Seyedeh Kimia Javadi Haghighi,Reza Fardid,Arash Safari
Seyedeh Kimia Javadi Haghighi
Background: Radiation therapy is the most common modality to treat various types of cancers. The use of radiosensitizers as an adjuvant therapy to increase the sensitivity of tumors against radiation and to improve the ef...
The Pharmacoeconomics and its Evaluation in Enhancing the Indian Healthcare System [0.03%]
药学经济学及其在印度医疗体系中的评估作用研究
Uma Agarwal,Garima Kapoor,Khushboo Singhal et al.
Uma Agarwal et al.
Introduction: Escalating healthcare costs and increasing demands on healthcare systems have increased the need for efficient resource allocation. Pharmacoeconomics is a vital field that quantifies and compares the value o...
The Potential of Coenzyme Q10 in Alzheimer's Disease: Reducing IL-17 Induced Inflammation and Oxidative Stress for Neuroprotection [0.03%]
辅酶Q10在阿尔茨海默病中的潜力：减少IL-17诱导的炎症和氧化应激以实现神经保护作用
Himanshu Sharma,Sumaiya Binte Ibrahim,Abdullah Al Noman et al.
Himanshu Sharma et al.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder primarily marked by amyloid-beta (Aβ) plaque accumulation and neurofibrillary tangles, which lead to cognitive decline. Oxidative stress and neuroinflammation are key con...
Diabetic Wound Healing: Mechanism and Treatment Strategies with a Special Focus on Angiogenesis [0.03%]
糖尿病伤口愈合：以血管生成为重点的机制和治疗策略
Ankita Wal,Nidhi Singh,Pranay Wal et al.
Ankita Wal et al.
Due to the numerous comorbidities associated with diabetes mellitus (DM), its complications of poor wound healing, persistent ulceration, and subsequent limb amputation, DM is becoming a major global health concern. The need for research at...
Plant Endophytes and their Secondary Metabolites: A Source of Bioactive Compounds [0.03%]
植物内生菌及其次级代谢产物：生物活性化合物的来源
Smita Narwal,Gurvirender Singh,Neha Yadav et al.
Smita Narwal et al.
Plant endophytes are microorganisms in plant tissues that help generate many secondary metabolites that are responsible for biological activity. These naturally occurring chemicals have lured the attention of researchers due to their applic...