Cardiotoxicity in Loperamide Misuse and Abuse - Insights into Clinical Evidence, Underlying Mechanisms, and Clinical Management [0.03%]
洛哌丁胺滥用和误用所致的心脏毒性：临床证据、潜在机制及临床处理方法的启示
Naina Mohamed Pakkir Maideen,Sulthan Al Rashid
Naina Mohamed Pakkir Maideen
Introduction: Loperamide is a commonly available over-the-counter (OTC) antidiarrheal medication that emerged as a drug of abuse due to its opioid-receptor agonist activity at higher doses. Although loperamide has been fo...
Hadi Jabbari
Hadi Jabbari
Introduction: Dendrimers are nanoscale, highly branched macromolecules with a well-defined core and multifunctional surface groups. They improve drug delivery by enhancing solubility, bioavailability, and targeted release...
Neuronal Interfaces in Bioelectronic Medicines for Unlocking Therapeutic Potential for ANS Issues [0.03%]
用于解锁自主神经系统疾病治疗潜力的生物电子药物中的神经接口
Gunjan,Shaweta Sharma,Jyoti Pandey et al.
Gunjan et al.
Introduction: Bioelectronic devices that alter autonomic nervous system (ANS) activity to treat a variety of disorders have been made possible by developments in neurotechnology, micro/nano-engineering, and biocompatible ...
Genetic Approaches in Zebrafish Neurology: Genetic, Drug and Therapy Insights [0.03%]
斑马鱼神经病学的基因方法：基因、药物和治疗的新见解
Archana Behera,Yuvashree Chandrasekaran,Namrutha Dhonthi Shekar et al.
Archana Behera et al.
Zebrafish (Danio rerio) has emerged as a valuable vertebrate model organism widely used in biological and biomedical research due to its rapid embryonic development, optical transparency, high fecundity, and genetic similarity to humans. Th...
Garcinia indica: A Multifaceted Phytomedicine Bridging Nutrition and Therapy [0.03%]
Garcinia 指示：连接营养和治疗的多面植物药
Madhav Khurana,Saksham Sharma,Shushank Mahajan et al.
Madhav Khurana et al.
Garcinia indica (Kokum), a tropical tree native to the Western Ghats of India, is an underutilized yet pharmacologically significant species in the family Clusiaceae. Traditionally used in food and folk medicine, Kokum has also attracted sc...
Advancements in Novel Drug Delivery Systems for Topical Management of Superficial Fungal Infections: A Detailed Review [0.03%]
新型药物输送系统在浅表真菌感染 topical management中的应用进展：综述
Rojalika Mohanty,Aradhana Panigrahi,Himansu Bhusan Samal et al.
Rojalika Mohanty et al.
Introduction: Superficial fungal infections, such as dermatophytosis, candidiasis, and pityriasis versicolor, are prevalent worldwide. They put a heavy burden on healthcare systems, mainly because infections often recur, ...
Effectiveness of Empirical Tacrolimus Dosing in Renal Graft Immunosuppression [0.03%]
基于肾移植患者药代动力学的Tacrolimus剂量估算模型临床有效性的评估研究
Monique Oliveira Soares,Lícia Alves,Ricardo José Costa Mattoso et al.
Monique Oliveira Soares et al.
Introduction: Kidney transplantation remains the most effective therapeutic option for patients with end-stage chronic kidney disease, as it significantly improves survival and quality of life. Long-term graft maintenance...
Decoding the Role of Nutrition and Foods in Augmenting Athletes Performance: A Review [0.03%]
营养与食物对运动员表现的积极作用：综述
Manoj Kumar Mishra,Guru Prasad Mohanta,Riaz Ahmad et al.
Manoj Kumar Mishra et al.
This article explores several food supplements that offer potential benefits for athletes' health, exercise adaptation, and recovery. Among these substances are omega-3 fatty acids, gelatin/collagen, probiotics, and certain dietary suppleme...
From Tradition to Trend: Scrutinizing the Logic behind Plant-based Drug Discovery [0.03%]
从传统到趋势：植物源药物发现的逻辑审视
Darshan Gowda Bharathi Srinivasa,Sunil Kumar Kadiri,Prashant Tiwari
Darshan Gowda Bharathi Srinivasa
Significant interest in drug discovery and therapeutic breakthroughs has been triggered by the revival of plant pharmacological research. Although plant-derived chemicals have been employed in contemporary medicine for centuries, technologi...
Lactobacillus plantarum as a Novel Modulator of Immune and Behavioral Recovery in Substance Use Disorders: A Hypothesis [0.03%]
植生乳杆菌在物质使用障碍中作为免疫和行为恢复的新型调节剂的假说
Jonaid Ahmad Malik
Jonaid Ahmad Malik
Substance Use Disorders (SUDs) are increasingly recognized as conditions driven by neuroimmune dysfunction, leading to neuroinflammation and immune dysregulation. Growing evidence highlights the microbiota-gut-brain axis as a critical regul...