Simran K Zandu,Hitesh Chopra,Inderbir Singh
Simran K Zandu
Background: Ionic liquids (ILs) are ionic compounds with highly tunable and remarkable properties which make them an important candidate in multiple domains such as extraction, synthesis, analytics, catalysis, biotechnolo...
Oral Modified Drug Release Solid Dosage Form with Special Reference to Design; An Overview [0.03%]
以设计为重点的口服固体缓控释药物制剂概述
Senthilkumar Murugesan,Byran Gowramma,Kaviarasan Lakshmanan et al.
Senthilkumar Murugesan et al.
Oral drug delivery is the most widely utilized route of administration among all the routes that have been explored for systemic delivery of drugs via pharmaceutical products of different dosage form and this oral route provides maximum act...
Affective Risk for Problem Drinking: Reciprocal Influences Among Negative Urgency, Affective Lability, and Rumination [0.03%]
冲动、情绪不稳定和反刍对问题饮酒的预测作用
Emily A Atkinson,Anna M L Ortiz,Gregory T Smith
Emily A Atkinson
Background: Affective disturbances have long been implicated in the onset and maintenance of problematic alcohol use. Affective risk theory for problem drinking has moved beyond early documentation that negative affect br...
In-silico Design, ADMET Screening, MM-GBSA Binding Free Energy of Some Novel Isoxazole Substituted 9-Anilinoacridines as HER2 Inhibitors Targeting Breast Cancer [0.03%]
新型异噁唑取代的9-(芳氨基)吖啶类化合物作为HER2抑制剂抗乳腺癌的计算机辅助药物设计及ADMET筛选与MM-GBSA结合自由能计算研究
Rajagopal Kalirajan,Arumugasamy Pandiselvi,Byran Gowramma et al.
Rajagopal Kalirajan et al.
Background: Human Epidermal development factor Receptor-2 (HER2) is a membrane tyrosine kinase which is overexpressed and gene amplified in human breast cancers. HER2 amplification and overexpression have been linked to i...
Michaël Cardinale,Pierre Esnault,Johan Schmitt et al.
Michaël Cardinale et al.
Background: Cocaine is one of the most widely used illicit drugs, and it is the most common cause of drug-related death. The association of cocaine use with acute heart failure is a rare occurrence. ...
Murilo Sérgio Valente-Aguiar,Teresa Magalhães,Ricardo Jorge Dinis-Oliveira
Murilo Sérgio Valente-Aguiar
Background: Carbon monoxide (CO) is a major and ubiquitous component of fire atmospheres produced when organic matter is burned in an inadequate supply of oxygen. Accidental poisoning by CO is common in cold climates wher...
Farshid Shamsaei,Mohammad Baanavi,Zahra Marzieh Hassanian et al.
Farshid Shamsaei et al.
Background: Effects of substance abuse frequently expand beyond the nuclear family. Extended family members can experience feelings of abandonment, anxiety, fear, anger, concern, embarrassment, or guilt. Thus, they may wi...
Even More Complex…. When Mental Disorder Meets Addiction in Youth: Dual Pathology [0.03%]
更加复杂……当精神疾病遇上青少年的瘾症：双重病征
Julio Torales,João M Castaldelli-Maia,Antonio Geraldo da Silva et al.
Julio Torales et al.
Background: The management of mental disorders in child and adolescent is challenging. In addition, when substance use disorders are associated with mental disorders, important complications are noted. Dual pathology and ...
John C Ashton
John C Ashton
Background: The degree to which cannabis use causes long term harm to mental functioning is contentious. Objective: To determine the ev...
Mini-Review: A Brief History of Nitrous Oxide (N2O) Use in Neuropsychiatry [0.03%]
简述：神经精神病学中一氧化二氮(N₂O)使用简史
Mark A Gillman
Mark A Gillman
Background: Joseph Priestley's discovery of nitrous oxide (N2O) was recorded in 1772. In the late 1790's, Humphry Davy experimented with the psychotropic properties of N2O, describing his observations in a book, published...