Significance of 1,3,4-Oxadiazole Containing Compounds in New Drug Development [0.03%]
含噁二唑基团化合物在新药研发中的意义
Kavita Rana,Salahuddin,Jagdish K Sahu
Kavita Rana
Background: Oxadiazole core displays various pharmacological properties among five membered nitrogen heterocyclic compounds, specially 1,3,4-oxadiazole containing molecules that have occupied a particular place in the fie...
Farhath Sherin,S Gomathy,Shanish Antony
Farhath Sherin
Sirtuins are NAD+ dependent enzymes that have a predominant role in neurodegenerative disorders and also regulate the inflammatory process, protein aggregation, etc. The relationships between sirtuins with that of the nervous system and neu...
Novel Applications of Nanotechnology in Controlling HIV and HSV Infections [0.03%]
纳米技术在控制HIV和HSV感染方面的新应用
Sai Akilesh M,Ashish Wadhwani
Sai Akilesh M
Infectious diseases have been prevalent for many decades and viral pathogens have caused global health crises and economic meltdown on a devastating scale. The high occurrence of novel viral infections in recent years, in spite of the progr...
João Mauricio Castaldelli-Maia,Felipe Gil,Antonio Ventriglio et al.
João Mauricio Castaldelli-Maia et al.
Background: As one of the forms of media and art most consumed in the world, Oscar- nominated movies should have their drug use representation monitored because of possibly influencing but also reflecting society's behavi...
The Role of Signaling Pathway in the Biological Cause of Rheumatoid Arthritis [0.03%]
信号通路在类风湿性关节炎发病机制中的作用研究
Rakesh Kumar Chauhan,Pramod Kumar Sharma,Shikha Srivastava
Rakesh Kumar Chauhan
Rheumatoid arthritis not only affects synovial joints but also many other sites including heart, blood vessels, and skins. It is more common in females than in males. The exact cause of rheumatoid arthritis is not well established, but the ...
Validation of Texas Christian University Psychosocial Functioning and Motivation Scales in Iranian Persons Who Use Drugs [0.03%]
德克萨斯基督教大学心理社会功能和动力学量表在伊朗药物使用者中的验证研究
Sana Shahrabadi,Amir Jalali,Rostam Jalali et al.
Sana Shahrabadi et al.
Background: The psychosocial functioning and motivation scales of the Texas Cristian University (TCU) were translated and validated for the Persons Who Use Drugs (PWUDs). ...
Design and Evaluation of Eudragit RS-100 Based Itraconazole Nanosuspension for Ophthalmic Application [0.03%]
基于Eudragit RS-100 的伊曲康唑纳米悬浮液的眼用制剂的设计与评估
Pravin Pawar,Anita Duduskar,Swati Waydande
Pravin Pawar
Background: Poor water soluble compounds are difficult to develop as drug products using conventional formulation techniques. Objective: ...
Comparative Study
Current drug research reviews. 2021;13(1):36-48. DOI:10.2174/2589977512666200929111952 2021
SeDeM Expert System, an Innovative Tool for Developing Directly Compressible Tablets: A Review [0.03%]
SeDeM专家系统：开发可直接压缩药片的创新工具综述
Inderbir Singh,Ajay Kumar Thakur,Rajni Bala et al.
Inderbir Singh et al.
Background: SeDeM (Sediment Delivery Model) expert system is a preformulation tool employed for evaluating direct compression suitability of various excipients. SeDeM is a 12 parameters derived diagram and SeDeM-ODT (Sedi...
Repurposing of Benzimidazole Scaffolds for HER2 Positive Breast Cancer Therapy: An In-Silico Approach [0.03%]
苯并咪唑结构在HER2阳性乳腺癌治疗中的新用途：一种基于计算的方法
Selvaraj Jubie,Uma Durai,Subbiah Latha et al.
Selvaraj Jubie et al.
Background: A newer trend has been seen recently to reuse the conventional drugs with distinct indications for the newer applications to speed up the drug discovery and development based on earlier records and safety data...
Comparative Study
Current drug research reviews. 2021;13(1):73-83. DOI:10.2174/2589977512999200821170221 2021
Identification of Drug Candidates for Breast Cancer Therapy Through Scaffold Repurposing: A Brief Review [0.03%]
通过结构再利用识别乳腺癌治疗药物候选物的简短评论
Jubie Selvaraj,Thangavelu Prabha,Neetu Yadav
Jubie Selvaraj
Conventional drug discovery is a time consuming and expensive expedition with less clinical preference achievement proportion intended for breast cancer therapy. Even if numerous novel approaches to the conformation of drugs have been intro...