Potential Drugs for the Treatment of COVID-19: Synthesis, Brief History and Application [0.03%]
新冠肺炎(COVID-19)治疗药物的研究、合成、历史及应用展望
Ekhlass Uddin,Raisul Islam,Ashrafuzzaman et al.
Ekhlass Uddin et al.
Coronaviruses (CoVs) belong to the Betacoronavirus group, an unusually large RNA genome characterized by club-like spikes that project from their surface. An outbreak of a novel coronavirus 2019 (nCOVID-19) already showed a unique replicati...
Supriya Kumari Singh,Saumya Chaubey,Anil Bansal et al.
Supriya Kumari Singh et al.
Azelaic acid (AZA) is a white crystalline dicarboxylic acid naturally found in grains, rye, and barley. AZA has substantial biological and therapeutic abilities (viz a viz) its anti-inflammatory, anti-oxidant, anti-keratinizing, anti-microb...
Effect of BMI on Prolonged Abstinence after Smoking Cessation Treatment: A Retrospective Cohort Study [0.03%]
体质指数对戒烟治疗后延长戒断效果的影响：一项回顾性队列研究
Fernanda Piotto Frallonardo,Danielle Ruiz Lima,Carlos Felipe Cavalcanti Carvalho et al.
Fernanda Piotto Frallonardo et al.
Background: Despite the well-documented relationship between weight gain and poorer cessation outcomes among smokers, the role of the former (baseline) weight in smoking cessation is insufficiently investigated. We hypoth...
Potential of Antibiotics for the Treatment and Management of Parkinson's Disease: An Overview [0.03%]
抗生素治疗和管理帕金森病的潜力：综述
Narayan Yadav,Ajit Kumar Thakur,Nikhila Shekhar et al.
Narayan Yadav et al.
Evidence has emerged over the last 2 decades to ascertain the proof of concepts viz. mitochondrial dysfunction, inflammation-derived oxidative damage and cytokine-induced toxicity that play a significant role in Parkinson's disease (PD). Th...
A Review on Repurposed Drugs and Vaccine Trials for Combating SARS CoV-2 [0.03%]
关于对抗SARS-CoV-2的药物再利用和疫苗试验的评论
Nikita Khanna,Sandip V Pawar,Anil Kumar
Nikita Khanna
Background: The novel coronavirus disease 2019 (COVID-19), emerged in Wuhan, China in December 2019 and then spread worldwide rapidly. The records from World Health Organisation (WHO), Centres of Disease Control and Preve...
Therapeutic Potential of Green Synthesized Metallic Nanoparticles Against Staphylococcus aureus [0.03%]
绿色合成金属纳米颗粒对抗金黄色葡萄球菌的治疗潜力
Meron Moges Tsegaye,Garima Chouhan,Molla Fentie et al.
Meron Moges Tsegaye et al.
Background: The recent treatment challenges posed by the widespread emergence of pathogenic multidrug-resistant (MDR) bacterial strains cause huge health problems worldwide. Infections caused by MDR organisms are associat...
Drug Repurposing: An Emerging Tool for Drug Reuse, Recycling and Discovery [0.03%]
药物再定位：一种新兴的药物重用、循环和发现工具
Supriya Roy,Suneela Dhaneshwar,Bhavya Bhasin
Supriya Roy
Drug repositioning or repurposing is a revolutionary breakthrough in drug development that focuses on rediscovering new uses for old therapeutic agents. Drug repositioning can be defined more precisely as the process of exploring new indica...
Low Doses Naltrexone: The Potential Benefit Effects for its Use in Patients with Cancer [0.03%]
低剂量纳洛酮的潜在益处及其在癌症患者中的应用效果
Ricardo David Couto,Bruno Jose Dumêt Fernandes
Ricardo David Couto
Naltrexone (NTX) is an opioid antagonist that inhibits cell proliferation in vivo when administered in low doses. Naltrexone in low doses can reduce tumor growth by interfering with cell signalling as well as by modifying the immune system....
Use of Medications for the Treatment of Alcohol Dependence: A Retrospective Study Conducted in 2011-2012 [0.03%]
我国2011-2012年酒精依赖药物治疗的用药现状调查
Roberta Agabio,Silvia Balia,Gian Luigi Gessa et al.
Roberta Agabio et al.
Background: Pharmacotherapy for Alcohol Dependence (AD) is underutilized. Barriers preventing the use of AD medications include high prices, lack of access to prescribing physicians, and a limited number of available medi...
Suberosin Attenuates the Proliferation of MCF-7 Breast Cancer Cells in Combination with Radiotherapy or Hyperthermia [0.03%]
白杨醇联合放疗或热疗抑制MCF-7乳腺癌细胞增殖作用研究
Saeedeh Jafari Nodooshan,Peyman Amini,Milad Ashrafizadeh et al.
Saeedeh Jafari Nodooshan et al.
Aim: The aim of this study was to determine the proliferation of MCF-7 following irradiation or hyperthermia as alone or pre-treatment with suberosin. Bac...