Carbapenem Antibiotics: Recent Update on Synthesis and Pharmacological Activities [0.03%]
碳青霉烯抗生素：合成和药理活性新进展
Abhishek Tiwari,Varsha Tiwari,Biswa Mohan Sahoo et al.
Abhishek Tiwari et al.
Right from the breakthrough of carbapenems since 1976, many schemes on synthesis, structure-activity relationship (SAR), and biological activities have been carried out, and several carbapenems have been developed, including parentally acti...
Are Herbal-peptides Effective as Adjunctive Therapy in Coronavirus Disease COVID-19? [0.03%]
中药活性肽在冠状病毒疾病COVID-19的辅助治疗中有效吗？
Elahe Aleebrahim-Dehkordi,Faezeh Soveyzi,Shirin Saberianpour et al.
Elahe Aleebrahim-Dehkordi et al.
Background: Plant antiviral peptides (AVP) are macromolecules that can inhibit the pathogenesis of viruses by affecting their pathogenic mechanism, but most of these peptides can bind to cell membranes, inhibit viral rece...
An In-silico Approach: Design, Homology Modeling, Molecular Docking, MM/GBSA Simulations, and ADMET Screening of Novel 1,3,4-oxadiazoles as PLK1inhibitors [0.03%]
一种基于计算机的方法：设计，同源模建，分子对接，MM/GBSA模拟及新型1,3,4-噁二唑类PLK1抑制剂的ADMET筛选
Sindhya Malkaje,Mahendra Gowdru Srinivasa,Shridhar Deshpande N et al.
Sindhya Malkaje et al.
Background: Breast cancer is the most commonly diagnosed and major cause of cancer-related deaths in women worldwide. Disruption of the normal regulation of cell cycle progression and proliferation are the major events le...
Time Depletion Effects on the Volatile Compounds from the Distillation Extracts of Prunella vulgaris and the Dynamics of their Extraction [0.03%]
蒸青提取物的挥发性成分及其浸提动力学的时效耗竭效应
William Chi Keung Mak
William Chi Keung Mak
Background: Prunella vulgaris (PV) is a low-growing perennial herb, which can be found in different parts of the world as Asia, Europe and North America. It is traditionally used for medicinal treatment in various culture...
Phytochemical and in-vitro Biological Investigation of Indian Traditional Medicinal Plants for their Cytotoxicity and Hepatoprotective Potential [0.03%]
印度传统药用植物的植物化学和体外生物研究及其 cytotoxicity 和 hepatoprotective 潜力
Mvnl Chaitanya,Jubie Selvaraj,Dhanabal Palanisamy et al.
Mvnl Chaitanya et al.
Objective: This study aimed to select 16 medicinal plants based on their folklore remedy for treating various diseases like inflammation, cancer, etc., and scientifically validate their potency. ...
Shilpa Kaore,Shubham Atal
Shilpa Kaore
Background: COVID-19, first detected in Wuhan, China, has evolved into a lifethreatening pandemic spread across six continents, with the global case count being more than 243 million, and mortality over 4.95 million, alon...
Dyslipidemia Secondary to the Use of HAART in Adults: A Systematic Review [0.03%]
高效抗逆转录病毒治疗导致成人继发性血脂异常的系统评价
Diogo Pereira Rodrigues Oliveira,Ana Paula Azevêdo Macêdo,Mariane Dos Santos Gonçalves et al.
Diogo Pereira Rodrigues Oliveira et al.
Background: HIV infection affects millions of people globally. Currently, although several drugs have brought an improvement in the quality and life expectancy of these individuals, they are accompanied by several adverse...
Vivekanand Vishvakarma,Malkiet Kaur,Manju Nagpal et al.
Vivekanand Vishvakarma et al.
One of the important parameters in the case of dosage form is taste. Most of the drugs available in oral dosage form have an unpleasant taste which leads to patient incompliance and affects the success ratio of products in the market. Geria...
Biochanin-A: A Bioactive Natural Product with Versatile Therapeutic Perspectives [0.03%]
生物活性天然产物Biochanin-A的多样治疗前景
Vadivelan Ramachandran,Inba Kumar V,Kiran Kumar Hr et al.
Vadivelan Ramachandran et al.
Background: Biochanin-A (5,7 dihydroxy 4 methoxy isoflavone) is a phytochemical phytoestrogen that is highly effective against various diseases. Biochanin-A is a nutritional and dietary isoflavonoid naturally present in r...
Plant-based Natural Products for Wound Healing: A Critical Review [0.03%]
伤口愈合的植物源天然药物研究进展及展望——一篇批判性评论
Shalini Ramalingam,Moola Joghee Nanjan Chandrasekar,Moola Joghee Nanjan
Shalini Ramalingam
Wound healing is an intricate process consisting of four overlapping phases, namely hemostasis, inflammation, proliferation, and remodelling. Effective treatment of wounds depends upon the interaction of appropriate cell types, cell surface...