A functional cell-based bioassay for assessing adrenergic autoantibody activity in postural tachycardia syndrome [0.03%]
用于评估直立性心动过速综合征中肾上腺素自动抗体活性的功能细胞生物测定法
Thariq Badiudeen,Elizabeth A Forsythe,Graham Bennett et al.
Thariq Badiudeen et al.
Background: Activating autoantibodies (AAb) to adrenergic receptors (AR) have previously been reported in patients with postural tachycardia syndrome (POTS). These AAb may contribute to a final common pathway for overlapp...
Identification and characterization of rare toll-like receptor 3 variants in patients with autoimmune Addison's disease [0.03%]
罕见的 Toll 样受体 3 在自身免疫性艾迪生病患者中的鉴定和特征分析
Sigrid Aslaksen,Anette B Wolff,Magnus D Vigeland et al.
Sigrid Aslaksen et al.
Autoimmune Addison's disease (AAD) is a classic organ-specific autoimmune disease characterized by an immune-mediated attack on the adrenal cortex. As most autoimmune diseases, AAD is believed to be caused by a combination of genetic and en...
Quantification of neutralizing anti-drug antibodies and their neutralizing capacity using competitive displacement and tandem mass spectrometry: Infliximab as proof of principle [0.03%]
利用竞争置换和串联质谱量化中和抗药抗体及其中和能力：英夫利昔单抗作为原理证明
Mohsin El Amrani,Camiel Göbel,Annelies C Egas et al.
Mohsin El Amrani et al.
Background: The development of anti-drug antibodies (ADA) in patients treated with therapeutic proteins can result in treatment failure. The clinically most relevant fraction of these antibodies are the neutralizing anti-...
Immunodietica: A data-driven approach to investigate interactions between diet and autoimmune disorders [0.03%]
免疫饮食学：一种数据驱动的方法来探究饮食和自身免疫疾病之间的相互影响
Iosif M Gershteyn,Leonardo M R Ferreira
Iosif M Gershteyn
Autoimmunity is on the rise around the globe. Diet has been proposed as a risk factor for autoimmunity and shown to modulate the severity of several autoimmune disorders. Yet, the interaction between diet and autoimmunity in humans remains ...
Human MOSPD2: A bacterial Lmb mimicked auto-antigen is involved in immune infertility [0.03%]
人类MOSPD2：一种细菌Lmb模拟的自身抗原参与免疫性不孕症
Rajeshwari Parida
Rajeshwari Parida
Autoantibody production is one of the leading factors of immune infertility, an autoimmune disease of the male reproductive system. The potential involvement of MHC-class II derived self-peptides against bacterial proteins in the antisperm ...
Immunodeficiency and Autoimmunity: The goals of the Journal of Translational Autoimmunity [0.03%]
免疫缺陷和自身免疫：《转化自身免疫学杂志》的目标
Christopher Chang,M Eric Gershwin
Christopher Chang
Pathogenic priming likely contributes to serious and critical illness and mortality in COVID-19 via autoimmunity [0.03%]
病原激活可能通过自身免疫导致新冠肺炎的重症化及死亡
James Lyons-Weiler
James Lyons-Weiler
Homology between human and viral proteins is an established factor in viral- or vaccine-induced autoimmunity. Failure of SARS and MERS vaccines in animal trials involved pathogenesis consistent with an immunological priming that could invol...
Therapeutic intervention in relapsing autoimmune demyelinating disease through induction of myelin-specific regulatory CD8 T cell responses [0.03%]
通过诱导髓鞘特异性调节性CD8 T细胞反应来治疗复发性自身免疫脱髓鞘疾病
Ashley A Brate,Alexander W Boyden,Farah R Itani et al.
Ashley A Brate et al.
Multiple Sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS). We have shown that CNS-specific CD8 T cells (CNS-CD8) possess a disease suppressive function in MS and its animal model, experimental autoim...
Angiotensin receptor autoantibodies as exposures that modify disease progression: Cross sectional, longitudinal and in vitro studies of prostate cancer [0.03%]
血管紧张素受体自身抗体作为可改变疾病进程的暴露因素：前列腺癌的横断面、纵向和体外研究
Alka Jain,Haikoo Shah,Eleanor M Simonsick et al.
Alka Jain et al.
Circulating angiotensin type I receptor (AT1R) agonistic autoantibodies (AT1RaAbs) that bind and chronically activate the receptor have been associated with a number of diseases suggesting that while the autoantibodies are not necessarily c...