Utility of the monocyte CD64/neutrophil CD64 ratio in autoimmune and autoinflammatory diseases: A retrospective observational study [0.03%]
自身免疫和自身炎症性疾病中单核细胞CD64/中性粒细胞CD64比值的临床意义：回顾性观察研究
Kazuhiro Itoh,Hiroshi Tsutani,Nozomi Otsuki et al.
Kazuhiro Itoh et al.
Distinguishing superimposed infection from disease flare in systemic autoimmune and autoinflammatory diseases remains challenging, because neutrophil CD64 (nCD64) is sensitive for infection but may have reduced specificity in this setting. ...
Anti-Annexin A5 antibodies and Annexin A5 resistance in antiphospholipid syndrome: A systematic review and meta-analysis [0.03%]
抗磷脂综合征中抗ANNEXIN A5抗体与ANNEXIN A5耐药性的关联：系统评价和meta分析
Laith Alamlih,Karima Becetti,Samar Al Emadi et al.
Laith Alamlih et al.
Objective: To provide an updated systematic review and meta-analysis of the estimated pooled of anti-Annexin A5 antibodies (AnxA5-Abs) and Annexin A5 resistance (A5R) across antiphospholipid syndrome (APS) phenotypes. ...
Biomarkers associated with Hashimoto's thyroiditis induced by viral infection: An integrative bioinformatics and machine learning [0.03%]
与病毒感染引起的桥本甲状腺炎相关的生物标志物：综合生物信息学和机器学习分析
Yuhan Zhang,Hanyu Wang,Mengfei Fu et al.
Yuhan Zhang et al.
Objective: Hashimoto's thyroiditis (HT) is a common disease characterized by autoimmune injury of the thyroid. Its pathogenesis entails complex interactions among hereditary predisposition, immune disorders and environmen...
Agonistic autoantibodies targeting AT1R and ETAR: Mechanistic insights and emerging implications in cardiovascular disease [0.03%]
靶向AT1R和ETAR的拮抗性自身抗体：机制见解及其在心血管疾病中的新含义
Francesco Tona,Giacomo Bernava,Giovanni Civieri
Francesco Tona
Autoimmune mechanisms are increasingly recognized as contributors to cardiovascular disease, extending beyond the traditional view of autoantibodies as passive markers of tissue injury. Among functional autoantibodies, those targeting the a...
Immunologic links between cutaneous lupus and internal organ involvement in SLE: A systematic review and meta-analysis [0.03%]
狼疮皮疹与系统性红斑狼疮内脏损害的相关性：系统性回顾和荟萃分析
Dasarina Rizqi Amalia,R Mohamad Javier,Laissa Bonita et al.
Dasarina Rizqi Amalia et al.
Background: Cutaneous lupus erythematosus (CLE) represents one of the most frequent clinical manifestations of systemic lupus erythematosus (SLE), yet its relationship with internal organ involvement remains incompletely ...
Longitudinal evolution of rheumatoid factor-expressing lymphoma precursors in a patient with Sjögren's disease [0.03%]
腮腺炎患者中类风湿因子表达淋巴瘤前体的纵向演变过程研究
Adrian Y S Lee,Jing Jing Wang,David A Brown et al.
Adrian Y S Lee et al.
Objective: Patients with Sjögren's disease (SjD) have an increased risk of developing B cell lymphomas, which may express rheumatoid factors (RhF). However, it remains unclear whether RhF-secreting cells undergo malignan...
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4): Between immune tolerance and genetic predisposition to Systemic Lupus Erythematosus (SLE) [0.03%]
细胞毒性T淋巴细胞相关蛋白4（CTLA-4）：介于免疫耐受和系统性红斑狼疮（SLE）的遗传易感性之间
Hajar Fadili,Mohammed Fahi,Abire Allaoui et al.
Hajar Fadili et al.
Gábor Nagy,Dóra Bencze,Sarolta Demeter et al.
Gábor Nagy et al.
Autoimmune hepatitis (AIH) is a rare, chronic, immune mediated liver disorder with unknown origin, associated with elevation of serum transaminases and IgG, positivity of certain autoantibodies and characteristic histopathological alteratio...
Autoantibodies in the diagnostics, prognostics and follow-up of primary biliary cholangitis [0.03%]
自身抗体在原发性胆汁性胆管炎诊断、预后和随访中的应用
Péter Antal-Szalmás,Dóra Bencze,Sarolta Demeter et al.
Péter Antal-Szalmás et al.
Primary biliary cholangitis (PBC), is a chronic autoimmune liver disease, characterized by cholangiopathy, cholestasis and in the long-term fibrosis, biliary cirrhosis and ultimately end-stage liver disease unless liver transplantation is a...
Ruxolitinib reverses alopecia areata via a triple mechanism: JAK-STAT inhibition, localized oxidative stress attenuation and selective apoptosis modulation [0.03%]
鲁索利替尼通过三联机制逆转斑秃：JAK-STAT抑制、局部抗氧化和选择性凋亡调控
Meiling Zhu,Hao Mu,Bo Wang et al.
Meiling Zhu et al.
Alopecia areata (AA) is an autoimmune hair loss disorder driven by the IFN-γ-JAK-STAT signaling and cytotoxic T-cell attack. Although JAK inhibitors like ruxolitinib show clinical efficacy, their integrated mechanism remains unclear. This ...