Miao Yang,Haijing Wu,Ming Zhao et al.
Miao Yang et al.
Bullous skin diseases are a group of dermatoses characterized by blisters and bullae in the skin and mucous membranes. The etiology and pathogenesis of bullous skin diseases are not completely clear. The most common are pemphigus and bullou...
Frequencies and clinical associations of myositis-related antibodies in The Netherlands: A one-year survey of all Dutch patients [0.03%]
荷兰肌炎相关抗体的频率和临床关联性研究：对所有荷兰患者的为期一年的调查
Anouk C M Platteel,Brigitte A Wevers,Johan Lim et al.
Anouk C M Platteel et al.
Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of connective tissue diseases, collectively known as myositis. Diagnosis of IIM is challenging while timely recognition of an IIM is of utter importance considering treatmen...
Jangampalli Adi Pradeepkiran
Jangampalli Adi Pradeepkiran
Rheumatoid arthritis (RA) is a defective post-translational modification of citrullinated peptides which cause synovial inflammation in joints. The present review elaborates the basic mechanisms of RA and the root causes of molecular mechan...
Paradoxical role of Breg-inducing cytokines in autoimmune diseases [0.03%]
诱导Breg细胞的细胞因子在自身免疫疾病中的矛盾作用
Fatin N Mohd Jaya,Sergio G Garcia,Francesc E Borràs et al.
Fatin N Mohd Jaya et al.
Regulatory B cells (Breg) are crucial immunoregulators that maintain peripheral tolerance and suppress inflammatory autoimmune responses. In recent years, our understanding on the nature and mechanism of action of Bregs has revealed the imp...
The skin microbiome in psoriatic disease: A systematic review and critical appraisal [0.03%]
银屑病中的皮肤微生物群系：系统回顾与批判性评估
Meital Yerushalmi,Ofir Elalouf,Melanie Anderson et al.
Meital Yerushalmi et al.
Background: Psoriasis affects 1-3% of the Canadian population. Psoriatic arthritis (PsA), the most common comorbidity of psoriasis, affects up to 30% of psoriasis patients. The skin microbiome is hypothesized to play a ro...
Potentially inappropriate anticholinergic drug prescriptions for patients with Sjögren's syndrome [0.03%]
可能不恰当的抗胆碱能药物对舍格伦综合征患者的处方问题
Luis Fernando Valladales-Restrepo,Jorge Enrique Machado-Alba
Luis Fernando Valladales-Restrepo
Sjögren's syndrome is characterized by the involvement of exocrine glands, manifesting with xerostomia and xerophthalmia. The objective was to determine the treatment received and identify potentially inappropriate prescriptions by estimat...
A functional cell-based bioassay for assessing adrenergic autoantibody activity in postural tachycardia syndrome [0.03%]
用于评估直立性心动过速综合征中肾上腺素自动抗体活性的功能细胞生物测定法
Thariq Badiudeen,Elizabeth A Forsythe,Graham Bennett et al.
Thariq Badiudeen et al.
Background: Activating autoantibodies (AAb) to adrenergic receptors (AR) have previously been reported in patients with postural tachycardia syndrome (POTS). These AAb may contribute to a final common pathway for overlapp...
Identification and characterization of rare toll-like receptor 3 variants in patients with autoimmune Addison's disease [0.03%]
罕见的 Toll 样受体 3 在自身免疫性艾迪生病患者中的鉴定和特征分析
Sigrid Aslaksen,Anette B Wolff,Magnus D Vigeland et al.
Sigrid Aslaksen et al.
Autoimmune Addison's disease (AAD) is a classic organ-specific autoimmune disease characterized by an immune-mediated attack on the adrenal cortex. As most autoimmune diseases, AAD is believed to be caused by a combination of genetic and en...
Quantification of neutralizing anti-drug antibodies and their neutralizing capacity using competitive displacement and tandem mass spectrometry: Infliximab as proof of principle [0.03%]
利用竞争置换和串联质谱量化中和抗药抗体及其中和能力：英夫利昔单抗作为原理证明
Mohsin El Amrani,Camiel Göbel,Annelies C Egas et al.
Mohsin El Amrani et al.
Background: The development of anti-drug antibodies (ADA) in patients treated with therapeutic proteins can result in treatment failure. The clinically most relevant fraction of these antibodies are the neutralizing anti-...
Immunodietica: A data-driven approach to investigate interactions between diet and autoimmune disorders [0.03%]
免疫饮食学：一种数据驱动的方法来探究饮食和自身免疫疾病之间的相互影响
Iosif M Gershteyn,Leonardo M R Ferreira
Iosif M Gershteyn
Autoimmunity is on the rise around the globe. Diet has been proposed as a risk factor for autoimmunity and shown to modulate the severity of several autoimmune disorders. Yet, the interaction between diet and autoimmunity in humans remains ...