Salvatore Cavallo
Salvatore Cavallo
Multiple sclerosis (MS) is widely acknowledged to be an autoimmune disease affecting the neuronal myelin structure of the CNS. Autoantigens recognized as the target of this autoimmune process are: myelin basal protein, anti-proteolipid prot...
Yhojan Rodríguez,Manuel Rojas,Diana M Monsalve et al.
Yhojan Rodríguez et al.
Objective: To determine the prevalence of thyroid autoantibodies and the associated factors in euthyroid subjects. Methods: 300 euthyro...
Comparative immunophenotyping of Saccharomyces cerevisiae and Candida spp. strains from Crohn's disease patients and their interactions with the gut microbiome [0.03%]
来自克罗恩病患者的模式生物酵母和白假丝酵母菌株的比较免疫表型及其与肠道微生物群的相互作用
Monica Di Paola,Lisa Rizzetto,Irene Stefanini et al.
Monica Di Paola et al.
Investigation of the fungal communities in animal models of Inflammatory Bowel Diseases (IBD) showed a controversial role of Saccharomyces cerevisiae and Candida spp. In health and disease. These conflicting observations could be ascribed t...
Antinuclear antibodies (ANA) patterns in paraneoplastic cerebellar degeneration during the course of disease and treatment protocols - A case report [0.03%]
伴有副肿瘤性小脑变性的抗核抗体(ANA)在疾病过程和治疗协议中的变化 – 一个病例报道
A Ćerimagić,N Džananović
A Ćerimagić
Paraneoplastic cerebellar degeneration (PCD) is a rare disease that is triggered by an abnormal immune response to a malignant tumor by cross-reaction of antibodies. The low prevalence of this condition has not allowed for large-scale rando...
A patient with primary biliary cholangitis, autoimmune hepatitis, and primary sclerosing cholangitis variant syndrome [0.03%]
原发性胆汁性胆管炎，自身免疫性肝炎和原发性硬化性胆管炎变异综合征患者
Benedetta Terziroli Beretta-Piccoli,Luca Mazzucchelli,Chiara Taiana et al.
Benedetta Terziroli Beretta-Piccoli et al.
Overlap between autoimmune hepatitis (AIH) and either primary biliary cholangitis (PBC) or primary sclerosing cholangitis (PSC) is not rare and has extensively been reported. We herein report the first well documented case of triple overlap...
CXCR3+ T cells in multiple sclerosis correlate with reduced diversity of the gut microbiome [0.03%]
多发性硬化症中CXCR3+ T细胞与肠道微生物群多样性的降低相关
Siobhán Ní Choileáin,Markus Kleinewietfeld,Khadir Raddassi et al.
Siobhán Ní Choileáin et al.
Multiple sclerosis (MS) is a genetically mediated autoimmune disease characterized by inflammation in the central nervous system (CNS). Disease onset is thought to occur when autoreactive T cells orchestrate a cascade of events in the CNS r...
Achille Marino,Francesca Tirelli,Teresa Giani et al.
Achille Marino et al.
Innate immune system represents the ancestral defense against infectious agents preserved along the evolution and species; it is phylogenetically older than the adaptive immune system, which exists only in the vertebrates. Cells with phagoc...
The immunobiology of humanized Anti-IL6 receptor antibody: From basic research to breakthrough medicine [0.03%]
人源化抗白细胞介素6受体抗体的免疫生物学：从基础研究到突破性医药
Yoshiyuki Ohsugi
Yoshiyuki Ohsugi
The clinical use of monoclonal antibodies is well established in human medicine and has been amongst the most important contributions of basic science to clinical disease. One such antibody, the humanized anti-human IL-6 receptor antibody, ...
Cathelicidin LL-37: A new important molecule in the pathophysiology of systemic lupus erythematosus [0.03%]
宿主防御肽LL-37在系统性红斑狼疮发病机制中的作用研究进展
Alejandro Moreno-Angarita,Cristian C Aragón,Gabriel J Tobón
Alejandro Moreno-Angarita
Cathelicidin LL-37 is an antimicrobial peptide that is synthesized by epithelial cells, neutrophils, or lymphocytes and act as an essential defense mechanism against bacterial, viral, or fungi infection of eukaryotic organisms. However, in ...
Programmed death ligand 2 - A link between inflammation and bone loss in rheumatoid arthritis [0.03%]
程序性死亡配体2 - 类风湿关节炎中连接炎症和骨质流失的因子
Stinne R Greisen,Tue W Kragstrup,Jesper Skovhus Thomsen et al.
Stinne R Greisen et al.
Objective: Active rheumatoid arthritis (RA) is accompanied by increased appendicular and axial bone loss, closely associated to the degree of inflammation. The programmed death-1 (PD-1) pathway is important for maintainin...