Autoantibody and biomarker detection in the follow-up of autoimmune diseases: state of the art and future perspectives [0.03%]
自身免疫疾病随访中自身抗体和生物标志物检测的最新研究进展及未来展望
Jan Damoiseaux,Yves Renaudineau
Jan Damoiseaux
Originally developed for the diagnosis of autoimmune diseases, the application of autoantibodies and related biomarkers has been extended in certain cases to monitor therapeutic efficacy and to predict disease recurrence and/or severity. Se...
Autoantibodies reactive with glomerular endothelial cells and podocytes in patients with membranous nephropathy [0.03%]
膜性肾病患者针对系膜细胞和足细胞的自身抗体反应的研究
Vojtech Petr,Shrey Purohit,Felix Poppelaars et al.
Vojtech Petr et al.
Rationale & objective: Membranous nephropathy (MN) is a glomerular disease caused by autoantibodies reactive with podocyte antigens. The most common antigen is the M-type phospholipase A2 receptor (PLA2R), but autoantibod...
Decoding ulcerative colitis pathogenesis through transcriptomics: from dysregulated gene networks to targeted intervention strategies [0.03%]
通过转录组学解码溃疡性结肠炎发病机制：从失调的基因网络到靶向干预策略
Xiang Zhu,Yujie Yang,Yi Zhu
Xiang Zhu
Background: Ulcerative colitis (UC) is an immune-mediated chronic inflammatory bowel disease, and with the rising global incidence and the risk of malignant transformation, the treatment of UC is challenged by heterogeneo...
Exploring the immunomodulatory effects of environmental contaminants on autoimmune patients: An in vitro approach [0.03%]
探索环境污染物对自身免疫疾病患者免疫调节作用：一种体外方法研究
Yeny Acosta-Ampudia,Diana M Monsalve,Daniel Galeano-Sánchez et al.
Yeny Acosta-Ampudia et al.
Background: Autoimmune diseases are multifactorial, with environmental contaminants increasingly recognized as risk factors. This pilot study investigated the in vitro effects of particulate matter (PM), silica, and 2,3,7...
Afucosylated IgG in idiopathic nephrotic syndrome patients with anti-nephrin autoantibodies correlate with disease activity [0.03%]
自身抗体阳性的原发性肾病综合征患者中缺乏岩藻糖的IgG与疾病活动相关
Sonia Spinelli,Andrea Garbarino,Francesca Lugani et al.
Sonia Spinelli et al.
Background: Idiopathic nephrotic syndrome (INS) is a glomerular disorder characterized by podocyte injury and proteinuria. Emerging evidence suggests that anti-nephrin autoantibodies (Abs) may contribute to disease pathog...
Corrigendum to 'Emerging cell-based and cell-free therapeutic strategies for vitiligo' [J. Transl. Autoimmun., 11 (2025), 100331] [0.03%]
关于“vitiligo的新兴细胞基质和无细胞治疗策略”的勘误[J. Transl. Autoimmun., 11 (2025), 100331]
Nasser Gholijani,Effat Noori,Zeinab Zarei-Behjani et al.
Nasser Gholijani et al.
[This corrects the article DOI: 10.1016/j.jtauto.2025.100331.]. © 2025 The Author(s).
Cell-specific epigenome-wide DNA methylation in peripheral CD4(+) lymphocytes from patients with primary biliary cholangitis [0.03%]
原发性胆汁性胆管炎患者外周CD4(+)淋巴细胞的细胞特异性DNA甲基化组图谱分析
Pinelopi Arvaniti,Kalliopi Zachou,Aggeliki Lyberopoulou et al.
Pinelopi Arvaniti et al.
Background/aims: Primary biliary cholangitis (PBC) is a chronic cholestatic autoimmune liver disease, triggered by a complex interplay between genetic, environmental and epigenetic factors. We investigated the methylation...
"CANDLE syndrome: A closer look at a rare autoinflammatory disorder" [0.03%]
烛焰征综合症：一种罕见的自身炎症性疾病的深入研究
Shivam Singh,Ashish Kumar Sharma
Shivam Singh
A newly identified autoinflammatory condition called CANDLE syndrome (chronic atypical neutrophilic dermatosis with lipodystrophy and increased temperature) is characterized by early onset, recurring fever, skin lesions, and multisystemic i...
Wenjie Zhu,Fan Li,Yuchen Zhang et al.
Wenjie Zhu et al.
Rheumatic heart disease (RHD), an autoimmune injury triggered by group A streptococcus (GAS) infection, exerts a significant pathological impact on the human heart. The pathogenesis of RHD is closely associated with abnormal epigenetic regu...
Data-driven classification of primary Sjögren's syndrome: From cluster analysis to clinical immune phenotypes and predictive biomarkers [0.03%]
基于数据的一类原发性舍格伦综合征的分类：从聚类分析到临床免疫表型和预测生物标志物
Jianbin Li,Suiran Li,Wei Liu
Jianbin Li
Background: Primary Sjögren's Syndrome (pSS) exhibits significant clinical heterogeneity, and traditional organ-based classification systems fail to capture the underlying disease mechanisms. This study aims to identify ...