Machine learning for predicting macrophage activation syndrome in adult patients with Still's disease [0.03%]
Yihe Zheng,Changyi Yang,Xiaoxuan Cai et al.
Yihe Zheng et al.
Background: Macrophage activation syndrome (MAS) secondary to Still's disease is a potentially fatal complication, associated with mortality rates exceeding 10%. Early identification is critical for survival but remains c...
Qi Wang,Mengjiao Chen,Hui Jin et al.
Qi Wang et al.
Cutaneous lupus erythematosus (CLE) is an inflammatory autoimmune disease characterized by specific skin lesions, differing from systemic lupus erythematosus (SLE) which affects multiple organs widely. Although CLE has traditionally been re...
A novel epigenetic regulation of JAM-A by EZH2-DNMT3A cascade contributes to T cell adhesion via the activation of Rap1a in lupus patients [0.03%]
EZH2-DNMT3A信号通路表观遗传学调节JAM-A的新机制在系统性红斑狼疮患者中促进T细胞活化及粘附
Lei Ding,Huan Gu,Yuting Zhong et al.
Lei Ding et al.
Objectives: The peripheral blood T cells epigenetic modification and adhesion capacity alterations are the characteristic of SLE. EZH2 induces proinflammatory epigenetic changes in immune regulation. JAM-A widely involves...
Intrathecal immunoglobulin production in the diagnosis, prognosis, and monitoring of autoimmune diseases of the central nervous system [0.03%]
免疫球蛋白的脑脊液内产生在中枢神经系统自身免疫性疾病的诊断、预后和监测中的作用
Yves Renaudineau,Bénédicte Puissant-Lubrano
Yves Renaudineau
Intrathecal immunoglobulin production is a hallmark of central nervous system (CNS) inflammation and can be observed in autoimmune disorders of the CNS, primarily multiple sclerosis (MS), but also in other inflammatory conditions such as MO...
Soluble immune checkpoints reflect immune activation and treatment response in high-risk systemic sclerosis patients treated with plasma exchange [0.03%]
血浆置换治疗高危系统性硬化病患者的可溶性免疫检查点反映免疫激活和治疗反应
Judith Potjewijd,Rachid Tobal,Daan P C van Doorn et al.
Judith Potjewijd et al.
Introduction: Systemic sclerosis (SSc) is an autoimmune disease characterized by immune dysregulation, vasculopathy, and fibrosis. High-risk patients, particularly those with diffuse cutaneous involvement (dcSSc) and inte...
GRN and KLRB1 define a shared peripheral-blood transcriptomic signature linking SLE and IPF [0.03%]
GRN和KLRB1定义了一个共享的外周血转录特征，把SLE和IPF联系起来
Lijun Pang,Yunfei Li,Junjie Chen et al.
Lijun Pang et al.
Background: Systemic lupus erythematosus (SLE) and idiopathic pulmonary fibrosis (IPF) share immune-inflammatory features, yet their convergent peripheral-blood transcriptomic signatures remain incompletely defined. We so...
Anti-IgLON5 encephalitis is associated with anti-retinal immunological reactivity without retinal alteration [0.03%]
抗IgLON5脑炎与无视网膜病理改变的抗视网膜免疫反应相关
Marie Rafiq,Fanny Varenne,Jérémie Pariente et al.
Marie Rafiq et al.
Anti-IgLON5 disease is a recently defined autoimmune disorder of the central nervous system associated with autoantibodies against IgLON5. This progressive condition, combining features of autoimmunity and neurodegeneration, presents with h...
Long-term natural history of thyroid peroxidase antibodies in a population-based cohort: Findings from 18 years of follow-up in Tehran Thyroid Study (TTS) [0.03%]
德黑兰甲状腺研究中人群基于队列的桥本甲状腺炎自身抗体长期自然病史：18年随访结果
Mohamadamin Tarighat-Payma,Ladan Mehran,Safdar Masoumi et al.
Mohamadamin Tarighat-Payma et al.
Background: Thyroid peroxidase antibody (TPOAb) is considered a highly sensitive marker of autoimmune thyroid diseases (AITD). Limited longitudinal data exist regarding its long-term natural history in the general populat...
Extracellular vesicles and their role in Lupus Nephritis: A scoping review [0.03%]
细胞外囊泡及其在狼疮性肾炎中的作用：系统综述
Lady J Rios-Serna,María Del Mar Rojas-Pelaez,Mildrey Mosquera Escudero et al.
Lady J Rios-Serna et al.
Lupus nephritis (LN) is one of the most severe and common complications of systemic lupus erythematosus (SLE), which pathogenesis is mainly driven by immune complex deposition and infiltration of immune cells, ultimately leading to progress...
Biopsy-proven myocarditis: peripheral immunophenotypes correlate with histology, etiology, immunosuppressive therapy [0.03%]
病理证实的心肌炎：外周免疫表型与组织学、病因及免疫治疗相关性
Cristina Vicenzetto,Andrea Silvio Giordani,Anna Baritussio et al.
Cristina Vicenzetto et al.
Background: Myocarditis is an inflammatory disease of the myocardium with infectious or immune-mediated/autoimmune etiology; etiology diagnosis relays on endomyocardial biopsy (EMB). High titre serum anti-heart autoantibo...