Tanner J Megna,Ana Bahamonde
Tanner J Megna
Ni-photochemical C-N couplings have emerged as a powerful synthetic tool. However, limitations in catalyst stability continue to constrain applicability. This Forum highlights how the field has evolved from reliance on Ir photocatalysts tow...
Dipankar Das,Long P Dinh,Ryan E Smith et al.
Dipankar Das et al.
Jarett M Posz,Anagha Veluthanath Nair,Ryan Van Hoveln et al.
Jarett M Posz et al.
Ashlyn Bohn,Benjamin M Cipriano,Peter Wipf
Ashlyn Bohn
The asymmetric partial reduction of substituted pyridines represents a direct and versatile strategy to access chiral di- and tetrahydropyridines, which are present in many natural products and active pharmaceutical ingredients (APIs). Howe...
Wynter A Paiva,Matthew E Currier,Samuel E Ashooh et al.
Wynter A Paiva et al.
DNA technology is rapidly expanding, with recent advances pushing functional DNA-based materials toward larger scales. Yet producing chemically modified DNA beyond the milligram-scale remains prohibitively expensive, challenging, and relati...
Kaila Nishikawa,Yael David,Anna Knörlein
Kaila Nishikawa
Cells regulate responses to external stimuli and control cell fate through reversible modifications on proteins, DNA, and RNA typically introduced by enzymes. Next to these well-known enzymatically installed modifications, covalent modifica...
Transition Metal Catalysis Drives Innovative Activity-Based Sensing Systems [0.03%]
过渡金属催化驱动创新型基于活性的传感系统
Autumn I Giger,Ramandeep Kaur,Nicholas J Dacon et al.
Autumn I Giger et al.
Through mechanistic understanding, transition metal catalysis has evolved into a key component of organic chemists' toolbox. Improvements in ligand design continue to push the boundaries of applications beyond targeted synthesis. This forum...
Gaoyuan Zhao,Arman Khosravi,Sahil Sharma et al.
Gaoyuan Zhao et al.
M Rafiul O K Noyon,Shabnam Hematian
M Rafiul O K Noyon
BURP domain peptide cyclases, or BpCs (an abbreviation we recommend in this opinion), are an emerging class of copper enzymes which catalyze the oxidative macrocyclization of peptides in plants. A close examination of their novel protein fo...
Joshua L Turnbull,Evan W Miller
Joshua L Turnbull
Fluorescent dyes are an indispensable part of the scientific enterprise. Xanthene-based fluorophores, like fluorescein and rhodamine, have been in continual use across numerous fields since their invention in the late 19th century. Modern m...