Estimating cardiovascular effects of influenza vaccination in older adults: a target trial emulation using proximal causal inference [0.03%]
利用接近因果推断估算流感疫苗接种对老年人心血管的影响:一种目标试验模拟方法
Jinxin Guo,Tiansheng Wang,Zhike Liu et al.
Jinxin Guo et al.
Background: The substantial burden of cardiovascular diseases highlights the urgent need for cost-effective interventions to mitigate their impact. While existing evidence on the cardioprotective effect of the influenza v...
Efficacy and safety of tazemetostat, an EZH2 inhibitor, in Chinese patients with relapsed/refractory follicular lymphoma: a multicentre, single-arm, phase 2 study [0.03%]
ezh2抑制剂tazelisert用于复发/难治滤泡性淋巴瘤中国患者的疗效和安全性:一项多中心、单组、Ⅱ期临床研究
Junning Cao,Guangliang Chen,Lihua Qiu et al.
Junning Cao et al.
Background: Tazemetostat, the first enhancer of zeste homolog 2 (EZH2) inhibitor approved by the U.S. Food and Drug Administration, has shown efficacy in a global population with relapsed or refractory (R/R) follicular ly...
Age-specific protective effects of statins against cirrhosis in patients with chronic liver enzyme elevation associated with metabolic dysfunction: a retrospective cohort study of electronic health records [0.03%]
他汀类药物对代谢功能障碍相关持续性肝酶升高患者的抗肝硬化年龄特异性保护作用:基于电子健康记录的回顾性队列研究
Ayako Suzuki,Georgia Sofia Karachaliou,Amy M Perkins et al.
Ayako Suzuki et al.
Background: The hepatoprotective effects of statins in chronic liver diseases are well-documented; however, variation by age, sex, and formulation remains unclear. The optimal regimen for cirrhosis prevention has yet to b...
Development and validation of machine learning models to predict esophagogastric variceal rebleeding risk in HBV-related cirrhosis after endoscopic treatment: a prospective multicenter study [0.03%]
预测乙型肝炎相关肝硬化患者内镜治疗后食管胃静脉曲张再出血风险的机器学习模型的开发和验证:一项前瞻性多中心研究
Linlin Zheng,Nannan Shi,Peizhao Li et al.
Linlin Zheng et al.
Background: Rebleeding after initial endoscopic therapy is associated with high mortality in patients with hepatitis B virus (HBV)-related liver cirrhosis complicated by esophagogastric variceal bleeding (EGVB), imposing ...
Response to "complexity of interstitial lung disease disproportionality signal analysis in pharmacovigilance databases" [0.03%]
对药物流行病学数据库中间质性肺疾病不对称信号分析的复杂性的回应
Zijun Zhu,Yongxin Li,Jiuda Zhao
Zijun Zhu
Dose-optimised recombinant human thrombopoietin versus eltrombopag in patients with immune thrombocytopenia: a multicenter, randomised controlled trial (The TE-ITP Study) [0.03%]
剂量优化的重组人血小板生成素与艾曲波帕治疗免疫性血小板减少症患者的疗效比较:一项多中心随机对照试验(TE-ITP研究)
Yunfei Chen,Ting Sun,Da Gao et al.
Yunfei Chen et al.
Background: Recombinant human thrombopoietin (rhTPO) at a fixed dose of 300 U/kg/day for 2 weeks has demonstrated good efficacy and safety in adults with immune thrombocytopenia (ITP). This trial aimed to develop a flexib...
Antibiotic treatment of pediatric infections in primary healthcare setting: evaluation and comparison of 80 national treatment guidelines with the WHO AWaRe book recommendations [0.03%]
基于WHO AWaRe用书的儿科感染性疾病抗生素治疗指南评估及比较研究(来自全球80个国家)
Daniele Donà,Giulia Brigadoi,Anna Cantarutti et al.
Daniele Donà et al.
Background: Antibiotic recommendations for pediatric infections in national standard treatment guidelines (STGs) vary widely, particularly for Access and Watch antibiotics. The WHO AWaRe book recommends Access antibiotics...
Two-year outcomes after selective early treatment of patent ductus arteriosus with ibuprofen in preterm babies: follow-up of Baby-OSCAR-a randomised controlled trial [0.03%]
早产儿动脉导管未闭选择性早期应用布洛芬治疗后的两年随访结果:Baby-OSCAR随机对照临床试验的后续研究
Samir Gupta,Heather OConnor,Edmund Juszczak et al.
Samir Gupta et al.
Background: Children born extremely preterm are at increased risk of developmental problems and respiratory morbidity due to patent ductus arteriosus (PDA). The objective of this study was to evaluate whether early treatm...
Impact of mode of offer of self-sampling to people overdue cervical screening on screening participation: a randomised controlled trial [0.03%]
提供自我检测样本进行宫颈筛查对滞后者参与筛查的影响:一项随机对照试验
Anita W W Lim,Rebecca Landy,Jane Rigney et al.
Anita W W Lim et al.
Background: Offering self-sampling to non-attenders increases cervical screening uptake, but the optimal approach for offering kits remains unclear. Metho...
Letting happiness happen [0.03%]
让幸福不期而至
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