Efficacy of lifestyle modification combined with GLP-1 receptor agonists on body weight and cardiometabolic biomarkers in individuals with overweight or obesity: a systematic review and meta-analysis [0.03%]
glucagon样肽-1受体激动剂与生活方式干预对超重或肥胖人群体重和心血管代谢标志物影响的系统评价和meta分析
Jiaheng Chu,Haibo Zhang,Yin Wu et al.
Jiaheng Chu et al.
Background: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are established treatments for obesity. However, it remains inconclusive whether the combination of lifestyle modifications and GLP-1RA interventions can le...
Physical morbidities in survivors of testicular germ cell tumors during childhood, adolescence, and young adulthood: a population-based retrospective matched cohort study [0.03%]
儿童、青少年及青年人睾丸生殖细胞瘤幸存者中的物理疾病负担：基于人群的回顾性队列研究
Rand Ajaj,Cindy Lau,Sumit Gupta et al.
Rand Ajaj et al.
Background: While testicular germ cell tumors (TGCT) survival exceeds 90%, many survivors of adult TGCT are at risk for treatment toxicities. Less is known about physical morbidities in children, adolescents, and young ad...
Impact of pulmonary rehabilitation programme design on effectiveness in COPD: a systematic review and component network meta-analysis [0.03%]
基于COPD患者肺康复项目设计的有效性系统评价及构成成分网络Meta分析
Thomas J C Ward,Lorna Latimer,Enya Daynes et al.
Thomas J C Ward et al.
Background: Pulmonary rehabilitation (PR) is a key treatment for chronic obstructive pulmonary disease (COPD) recommended by all guidelines. However, programmes vary widely and the optimal combination of components to max...
Therapeutic efficacy of Cyclosporine A in recurrent spontaneous abortion: a meta-analysis and network meta-analysis incorporating Chinese and English language studies [0.03%]
环孢素A治疗复发性流产的疗效：纳入中英文文献的meta分析与网络Meta分析
Xianyang Hu,Xixi Huang,Tingxuan Yin et al.
Xianyang Hu et al.
Background: Recurrent spontaneous abortion (RSA) poses a significant clinical challenge for childbearing women. Cyclosporine A (CsA), first introduced by our group for RSA treatment, has gained wide clinical application i...
Complexity of interstitial lung disease disproportionality signal analysis in pharmacovigilance databases [0.03%]
药物流行病学数据库中间质性肺疾病不对称信号分析的复杂性
Romane Freppel,Alex Hlavaty,Imen Bari et al.
Romane Freppel et al.
Supplemental parenteral nutrition within an enhanced recovery program for open pancreatoduodenectomy for cancer: a pragmatic, multicenter, randomized controlled trial [0.03%]
一种改良型围手术期处理方案中的补充性肠外营养：胰十二指肠切除术患者的多中心随机对照试验
Luca Gianotti,Salvatore Paiella,Giovanni Capretti et al.
Luca Gianotti et al.
Background: The role of supplemental parenteral nutrition (SPN) following pancreatoduodenectomy (PD) in the context of an enhanced recovery program is unexplored. This study aimed to determine whether SPN is superior to e...
Development and validation of an interpretable multi-task model to predict outcomes in patients with rhabdomyolysis: a multicenter retrospective cohort study [0.03%]
一项多中心回顾性队列研究：开发和验证一种可解释的多任务模型以预测横纹肌溶解症患者的预后
Chunli Liu,Jie Shi,Fengjuan Wang et al.
Chunli Liu et al.
Background: Rhabdomyolysis (RM) is a complex clinical syndrome with heterogeneous progression patterns among patients of varying severity. Early and accurate prediction of acute kidney injury (AKI), disease severity, rena...
Arterial and venous thromboembolic events in patients with cancer treated with targeted therapies: a population-based cohort study [0.03%]
基于人群的队列研究：在癌症患者中使用靶向疗法治疗患者的动脉和静脉血栓栓塞事件
Florian Moik,Erzsébet Horváth-Puhó,Cihan Ay et al.
Florian Moik et al.
Background: Emerging data suggest a substantial risk of arterial and venous thromboembolic events (ATE/VTE) associated with targeted cancer therapies. We examined the association between selected targeted therapies and AT...
Development of a core patient-centred outcome set for adults living with obesity: a modified delphi-based international consensus [0.03%]
基于患者中心结果集的肥胖成年人核心共识集的发展：国际共识调查
Teferi Mekonnen,Leanne Staniford,Spencer Connell et al.
Teferi Mekonnen et al.
Background: Obesity is a chronic disease linked to over 200 health conditions, reduced quality of life, and increased mortality. Despite the availability of multimodal treatments, there is a lack of standardised, patient-...
Immunogenicity and safety of self-amplifying mRNA COVID-19 vaccine (ARCT-2303), with or without co-administration of seasonal inactivated influenza vaccine in adults: a phase 3, randomised, controlled, observer-blind, multicentre study [0.03%]
具有或不具有季节性灭活流感疫苗联合给药的自我扩增型新冠 mRNA 疫苗（ARCT-2303）在成人的免疫原性和安全性：一项随机、对照、观察者设盲及多中心三期研究
Michelle L Giles,Charissa Tabora,Carmen Baccarini et al.
Michelle L Giles et al.
Background: A recently licenced self-amplifying mRNA (sa-mRNA) COVID-19 vaccine induces a robust, broad, and long-lasting immune response, extending the arsenal of efficacious COVID-19 countermeasures. We ran a clinical s...