Spinal cord stimulation for the treatment of painful diabetic neuropathy and risk of major adverse cardiovascular events, mortality, amputation, infection and suicide: a retrospective cohort study [0.03%]
脊髓刺激治疗糖尿病性疼痛性神经病变与主要不良心血管事件、死亡率、截肢术、感染和自杀风险：回顾性队列研究
Alex E Henney,Bernhard Frank,David R Riley et al.
Alex E Henney et al.
Background: Spinal cord stimulation (SCS) has recently been approved by the US Food and Drug Administration (FDA) for the treatment of refractory painful diabetic neuropathy (PDN), although the current evidence for effica...
Long-term safety of mid-urethral sling for stress urinary incontinence in women: an emulated trial using French national health data system [0.03%]
法国国家健康数据系统下中尿道悬吊带治疗压力性尿失禁长期安全性的仿真试验
Cyrille Guillot-Tantay,Sylvie Guillo,Minh Hoang Thuy Diep Tran et al.
Cyrille Guillot-Tantay et al.
Background: Mid-urethral sling (MUS) is the most-indicated therapy for treating stress urinary incontinence (SUI) in women. However, serious long-term side effects have escaped post-marketing studies. We aimed to compare ...
Laboratory evaluation of 185 commercial assays for detecting SARS-CoV-2: the UK response for mass testing [0.03%]
针对SARS-CoV-2的商业检测试剂评估：英国的大规模检测应对措施
Abbie Bown,Tim Peto,Angela Sweed et al.
Abbie Bown et al.
Background: In August 2020, Public Health England and Oxford University were commissioned to design and deliver (with NHS Test and Trace, NHSTT) a rapid evaluation programme of antigen Lateral Flow Devices (LFDs) for SARS...
eClinicalMedicine
eClinicalMedicine
Evaluation of SARS-CoV-2 lateral flow device sensitivity: a comparison of systematic laboratory assessments with manufacturer-reported sensitivity [0.03%]
SARS-CoV-2侧向流动装置灵敏度的评估：系统实验室评估与制造商报告的灵敏度的比较
Raghavendran Kulasegaran-Shylini,Abbie Bown,Tom Collinge et al.
Raghavendran Kulasegaran-Shylini et al.
Background: Self-testing for SARS-CoV-2 infection using lateral flow devices (LFDs) was a key component of the COVID-19 pandemic response; however, LFD performance has shown a high degree of variability. Between August 20...
Evaluation of safety of preoperative GLP-1 receptor agonists in patients undergoing elective surgery: a systematic review, meta-analysis and meta-regression [0.03%]
短效GLP-1受体激动剂应用于择期手术患者安全性系统评价：系统综述、荟萃分析及荟萃递归分析
Sivesh K Kamarajah,Nadia Gudiozzi,John M Findlay et al.
Sivesh K Kamarajah et al.
Background: Obesity remains a major global public health challenge, particularly among surgical patients, where it can be associated with increased perioperative and longer-term risk. While preoperative weight management ...
Incidence of suicide within two years of a first diagnosis of depression, anxiety, or mixed anxiety and depression: an exploratory cohort study in primary care using the Clinical Practice Research Datalink [0.03%]
一项初级保健队列研究：利用临床实践研究数据链探讨首次诊断为抑郁症、焦虑症或混合型焦虑抑郁两年内自杀发生的比例——一项探索性队列研究
James Bailey,Patricia Schartau,Seena Fazel et al.
James Bailey et al.
Background: The risk of suicide following first diagnosis of depression or anxiety in primary care is uncertain. We investigated suicide incidence within two years of a first diagnosis of depression, anxiety, or mixed anx...
Streptococcal endocarditis: a meta-analysis of species dependant risk [0.03%]
链球菌心内膜炎的meta分析：种类依赖风险不同
Gavin Deas,Todd C Lee,Julia Colston et al.
Gavin Deas et al.
Background: Streptococcal infective endocarditis (IE) is a devastating disease. In international guidance, the risk of IE from streptococci is considered the same regardless of species (excluding Streptococcus pyogenes an...
Osimertinib plus consolidative radiotherapy for advanced EGFR mutant non-small cell lung cancer: a multicentre, single-arm, phase 2 trial [0.03%]
阿法替尼联合巩固放疗治疗晚期表皮生长因子受体突变非小细胞肺癌的Ⅱ期临床研究
Sagus Sampath,Sawsan Rashdan,Puneeth Iyengar et al.
Sagus Sampath et al.
Background: Despite high response rates to epidermal growth factor receptor (EGFR) inhibitors, patients with advanced EGFR mutant non-small cell lung cancer (NSCLC) generally experience disease progression within 2 years....
The prevalence and risk of mortality associated with antimicrobial resistance within nosocomial settings-a global systematic review and meta-analysis of over 20,000 patients [0.03%]
一项关于全球医院内抗菌素耐药感染患病率和死亡风险的系统评价与meta分析（涉及20000多例患者）
Nisha A George,Daniel Pan,Luisa Silva et al.
Nisha A George et al.
Background: Bacterial antimicrobial resistance (AMR) is a leading cause of death globally. However, there has been no data synthesis on whether it influences mortality within hospital settings. We conducted a systematic r...