Exploring the genetics of airflow limitation in lung function across the lifespan - a polygenic risk score study [0.03%]
生命周期中肺功能气流限制的遗传学研究——基于多基因风险评分的研究
Natalia Hernandez-Pacheco,Anna Kilanowski,Ashish Kumar et al.
Natalia Hernandez-Pacheco et al.
Background: Chronic obstructive pulmonary disease (COPD) is caused by interactions between many factors across the life course, including genetics. A proportion of COPD may be due to reduced lung growth in childhood. We h...
Total neoadjuvant treatment using short-course radiotherapy and four CAPOX cycles in locally advanced rectal cancer with high-risk criteria for recurrence: a Swedish nationwide cohort study (LARCT-US) [0.03%]
新辅助放化疗联合卡培他滨治疗局部进展期高危直肠癌的疗效分析：瑞典全国队列研究(LARCT-US)
Bengt Glimelius,Tanweera Khan,Karin Adolfsson et al.
Bengt Glimelius et al.
Background: Total neoadjuvant treatment (TNT) for locally advanced rectal cancer (LARC) increases pathologic complete response (pCR) rate and reduces the risk of systemic recurrences over chemoradiotherapy (CRT) in random...
Impact of sedative and appetite-increasing properties on the apparent antidepressant efficacy of mirtazapine, selective serotonin reuptake inhibitors and amitriptyline: an item-based, patient-level meta-analysis [0.03%]
基于条目的患者水平meta分析：镇静和促食欲作用对米氮平、选择性5-羟色胺再摄取抑制剂和阿米替林表观抗抑郁疗效的影响
Fredrik Hieronymus,Alexander Lisinski,Elias Eriksson
Fredrik Hieronymus
Background: In an influential network meta-analysis, the tricyclic antidepressant (TCA) amitriptyline was found to be the most efficacious of 21 antidepressants, hence outranking selective serotonin reuptake inhibitors (S...
The hockey fans in training intervention for men with overweight or obesity: a pragmatic cluster randomised trial [0.03%]
针对超重或肥胖男性的冰球粉丝训练干预措施：实用集群随机试验
Robert J Petrella,Dawn P Gill,Nárlon C Boa Sorte Silva et al.
Robert J Petrella et al.
Background: Obesity disproportionately impacts men's health yet fewer men engage in preventive healthcare. We examined the effectiveness of Hockey Fans in Training (Hockey FIT), a gender-sensitised lifestyle intervention ...
Deep learning model for automated diagnosis of moyamoya disease based on magnetic resonance angiography [0.03%]
基于磁共振血管造影的 Moyamoya 病自动化诊断深度学习模型
Mingming Lu,Yijia Zheng,Shitong Liu et al.
Mingming Lu et al.
Background: This study explores the potential of the deep learning-based convolutional neural network (CNN) to automatically recognize MMD using MRA images from atherosclerotic disease (ASD) and normal control (NC). ...
The value of diagnostic imaging for enhancing primary care in low- and middle-income countries [0.03%]
诊断影像在低收入和中等收入国家改善初级护理中的作用
Vaidehi Nafade,Paulami Sen,Matthew Arentz et al.
Vaidehi Nafade et al.
Incidence of post-acute COVID-19 symptoms across healthcare settings in seven countries: an international retrospective cohort study using routinely-collected data [0.03%]
七国医疗环境下后急性期新冠肺炎症状的发病情况：使用常规收集数据进行国际回顾队列研究
Junqing Xie,Kim López-Güell,Daniel Dedman et al.
Junqing Xie et al.
Background: The World Health Organisation (WHO) has identified a range of symptomatic manifestations to aid in the clinical diagnosis of post-COVID conditions, herein referred to as post-acute COVID-19 symptoms. We conduc...
The performance of a point-of-care test for the diagnosis of Neurocysticercosis in a resource-poor community setting in Zambia - a diagnostic accuracy study [0.03%]
赞比亚贫困地区用于神经囊尾蚴病诊断的POCT检测性能研究-一项诊断准确性研究
Gideon Zulu,Dominik Stelzle,Kabemba E Mwape et al.
Gideon Zulu et al.
Background: Neurocysticercosis (NCC) is the main cause of epilepsy in Taenia solium endemic rural communities. NCC diagnosis is difficult due to unavailability and unaffordability of serologic assays and neuroimaging. Thi...
Development and validation of an interpretable machine learning model for predicting the risk of distant metastasis in papillary thyroid cancer: a multicenter study [0.03%]
一种用于预测乳头状甲状腺癌远处转移风险的可解释机器学习模型的开发与验证：一项多中心研究
Fei Hou,Yun Zhu,Hongbo Zhao et al.
Fei Hou et al.
Background: The survival rate of patients with distant metastasis (DM) of papillary thyroid carcinoma (PTC) is significantly reduced. It is of great significance to find an effective method for early prediction of the ris...
Brian Hutchinson,Rory Watts,Mary Nyangasi et al.
Brian Hutchinson et al.
Background: Cancer is the third leading cause of death in Kenya. Breast cancer is responsible for 3100 deaths annually. Quantifying the economic and social impacts of breast cancer supports inclusion of cancer care within...