Safety of budesonide/glycopyrronium/formoterol fumarate dihydrate delivered by HFO-1234ze versus HFA-134a in chronic obstructive pulmonary disease: a phase 3, multi-site, randomised, double-blind, parallel-group, active-comparator study [0.03%]
使用HFO-1234ze递送布地奈德/格隆溴铵/富马酸福莫特罗与HFA-134a递送相比治疗慢性阻塞性肺病的安全性：一项多中心、随机、双盲、平行分组、阳性药对照的III期研究
Omar S Usmani,Fernando J Martinez,Hitesh Pandya et al.
Omar S Usmani et al.
Background: Pressurised metered dose inhalers (pMDIs) contain a hydrofluorocarbon propellant, such as hydrofluoroalkane-134a (HFA-134a), which is known to have global warming potential (GWP). Transitioning pMDIs to propel...
Effectiveness of family-based behavioral intervention for smoking cessation in low-income households: a systematic review and meta-analysis [0.03%]
低收入家庭基于行为的家庭戒烟干预效果的系统综述和meta分析
Meng Yao Li,Tzu Tsun Luk,Derek Yee Tak Cheung et al.
Meng Yao Li et al.
Background: Smoking-attributable harms are substantial in low-income households. The effectiveness of family-based behavioral interventions for smoking cessation in this population remains uncertain. This review aims to a...
An artificial intelligence model integrating culprit lesion diagnosis and risk assessment for acute coronary syndrome [0.03%]
一种结合罪犯病变诊断和风险评估的急性冠脉综合征人工智能模型
Peng Peng Xu,Bin Hu,Fan Zhou et al.
Peng Peng Xu et al.
Background: An integrated machine learning (ML) approach capable of both diagnosing acute coronary syndrome (ACS, encompassing myocardial infarction and unstable angina) and predicting future ACS risk within defined optim...
Dietary attribution to burden of chronic disease in Australia: a systematic analysis of the Australian Institute of health and welfare 2024 national burden of disease dataset [0.03%]
澳大利亚2024年卫生福利研究所疾病负担数据集的饮食与慢性病负担归因分析体系研究
Yuanxin Xu,Jing Sun
Yuanxin Xu
Background: Non-communicable chronic diseases (NCDs), including cardiovascular diseases, cancer, chronic kidney disease (CKD), and type 2 diabetes mellitus (T2DM), pose a significant burden on Australia's healthcare syste...
Impact of metabolic dysfunction on treatment responses to nucleos(t)ide analogues in chronic hepatitis B: a retrospective multi-center REAL-B cohort study [0.03%]
代谢功能障碍对慢性乙型肝炎患者核苷(酸)类似物治疗反应的影响：REAL-B队列的多中心回顾性研究
Rui Huang,Dae Won Jun,Hidenori Toyoda et al.
Rui Huang et al.
Background: Metabolic dysfunction is associated with liver disease but it is unclear if it would impact responses to antiviral treatment in chronic hepatitis B (CHB) patients. ...
Safety and effectiveness of the early-onset sepsis calculator to reduce antibiotic exposure in at-risk newborns: a cluster-randomised controlled trial [0.03%]
一项集群随机对照试验：早发性败血症计算器用于减少高危新生儿抗生素暴露的安全性和有效性
Bo M van der Weijden,Sanne W C M Janssen,Marijke C van der Weide et al.
Bo M van der Weijden et al.
Background: Newborns are at risk for early-onset sepsis (EOS), occurring 0.2-2.0 per 1000 live births, and for antibiotic overtreatment: approximately 5-15% receive antibiotics for suspected EOS under conventional guideli...
Trastuzumab deruxtecan in patients from China with previously treated human epidermal growth factor receptor 2-positive locally advanced/metastatic gastric or gastroesophageal junction adenocarcinoma (DESTINY-Gastric06): results from a single-arm, multicenter, phase 2 trial [0.03%]
关于先前治疗过的HER2阳性局部晚期或转移性胃癌或胃食管交界腺癌中国患者使用德喜曲妥单抗治疗的二期、多中心单一组试验（DESTINY-Gastric06）的研究结果
Zhi Peng,Ping Chen,Jin Lu et al.
Zhi Peng et al.
Background: Trastuzumab deruxtecan (T-DXd; 6·4 mg/kg) is approved for metastatic human epidermal growth factor receptor 2 (HER2)-positive (HER2+) gastric or gastroesophageal junction (GEJ) adenocarcinoma after a trastuzu...
Evaluating the risk of digestive system cancer in autoimmune disease patients: a systematic review and meta-analysis focusing on bias assessment [0.03%]
自身免疫性疾病患者消化系统癌症风险的评估：以偏倚评估为重点的系统评价和meta分析
Julia Reizner,Simone Fischer,Jakob Linseisen et al.
Julia Reizner et al.
Background: There is emerging evidence that certain autoimmune diseases can modulate the risk for digestive system cancer. However, limitations of non-experimental studies may lead to diverging results. Thus, the aim was ...
A simple VA-ECMO bundle in adult patients with cardiogenic shock: an analysis of ELSO registry [0.03%]
成人心血管源性休克患者VA-ECMO简易操作程序包：ELSO注册中心分析结果
Liangshan Wang,Kexin Wang,Yan Wang et al.
Liangshan Wang et al.
Background: The optimal management strategy for patients undergoing veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for cardiogenic shock (CS) remains uncertain. To evaluate the impact of "bundled" physiologic...
Regional lymph node invasion in pediatric non-rhabdomyosarcoma soft tissue sarcoma: an international cohort study from the International Soft Tissue Sarcoma Consortium [0.03%]
儿童非横纹肌肉瘤软组织肉瘤区域淋巴结侵犯的国际队列研究：来自国际软组织肉瘤联盟的数据分析
Daniel Orbach,Matthieu Carton,Amadeus T Heinz et al.
Daniel Orbach et al.
Background: In pediatric non-rhabdomyosarcoma soft tissue sarcoma (NRSTS), the frequency and prognostic impact of regional lymph node involvement (N1) are not clearly defined and may vary according to histological type. W...